Sentences with phrase «in response to viral infections»

Chakrabarti, A., Ghosh, P.K., Banerjee, S., Gaughan, C., and Silverman, R.H. RNase L triggers autophagy in response to viral infections.

Interferons are produced naturally by the body in response to viral infection.

Not exact matches

In comparison with African strains, infection by the Asian strain of Zika virus more potently affected the p53 gene and genes connected with cells» responses to viral infection, such as interferons.

Based primarily at Harvard with Maniatis, tenOever developed a knockout mouse model to study a particular protein, IKKε, that's involved in the immune response to viral infection.

The vaccine also induced a sharp rise in CD4 T - cells, whose job is to mobilize the antibody response and other immune elements against viral infections.

Interferons are molecules produced by cells in response to viral or bacterial infection, and which act on neighboring cells to prevent the spread of the infection, shut down protein synthesis, and activate the immune system.

Research has already shown that immune response provided by nasal mucous membranes is compromised in cigarette smokers, which causes them to be more susceptible to the outcomes of a viral infection, said Ilona Jaspers, deputy director of the Center for Environmental Medicine Asthma and Lung Biology at the University of North Carolina at Chapel Hill, but her new research revealed even more immune suppression effects in e-cigarette users than in smokers of traditional cigarettes.

In findings they call counterintuitive, a team of UCLA - led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help combat HIV.

Interest in studying tRNA fragments has been increasing swiftly as studies have shown that the fragments have regulatory roles and implicated individual fragments in cellular processes such as translation initiation, response to viral infection, response to DNA damage, etc..

In the study, the researchers detected a very small number of SIV infected cells in the gut within initial 2.5 days of viral infection; however, the inflammatory response to the virus was playing havoc with the gut lininIn the study, the researchers detected a very small number of SIV infected cells in the gut within initial 2.5 days of viral infection; however, the inflammatory response to the virus was playing havoc with the gut lininin the gut within initial 2.5 days of viral infection; however, the inflammatory response to the virus was playing havoc with the gut lining.

The scientists believe that the heightened immune response to viral infection in the mother's body may be responsible for disrupting the timing of microglia development.

Maybe this little pause is an opportunity for a reset — a chance for the scientific community to acknowledge that the CRISPR system, as some have quietly suggested all along, was actually «invented» by bacteria eons ago as an ingenious immune response to viral infection, and that its rediscovery was accomplished by so many heroic (if you will) hands and with so much public coin that the technology ultimately belongs in the public commons and should not be patented and...

«While the prevailing wisdom would suggest that vaccines that make really strong CD4 T cell responses would, in their helper capacity, strengthen the responses of both antibodies and CD8 T cells, we often see that vaccines and viral infections seem to generate fewer CD4 responses than they do CD8 responses,» says Penaloza - MacMaster.

Studies by Shibo Jiang at Fudan University in Shanghai, China, and colleagues have found that the bit of the viral surface protein that attaches to a cell during infection — the binding site — only induces the right kind of antibody response.

Perry, A. K., Chow, E. K., Goodnough, J. B., Yeh, W. C. & Cheng, G. Differential requirement for TANK - binding kinase - 1 in type I interferon responses to Toll - like receptor activation and viral infection.

He and his colleagues were the first to demonstrate that human antigen - specific T cell clones could be isolated and expanded in vitro and then re-infused into patients to prevent or treat viral infections and to mediate therapeutic responses in patients with cancer.

«The observed increase in the ratio of cytotoxic CD4 T cells to CD4 helper T cells indicates that they are an important component of the protective immune response to viral infections and that their induction should be an important marker for successful vaccinations against certain viral diseases,» says postdoctoral researcher and first author Veena Patil, Ph.D. «But we really didn't know enough about their molecular profile and the mechanisms that drive their differentiation and maintenance.»

Mark did his postdoctoral work with Dr. Lewis Lanier at the University of California, San Francisco, where he researched the response of natural killer (NK) cells to viral infection, studying both the signaling pathways and educational programs that shape NK cell responses to infection in vivo.

His discoveries include insights into how changes in gene expression affect T cell exhaustion, a waning of immune function that occurs in response to chronic viral infection and cancer.

Tracking Carabin to its origins, the researchers said they were surprised to learn that viral infection not only turns on the immune system machinery, but also triggers the making of Carabin, which in turn shuts off the immune response.

Salicylic Acid: A Likely Endogenous Signal in the Resistance Response of Tobacco to Viral Infection

Although vaccination induces an inflammatory response during pregnancy, the magnitude and the duration of response is much lower and shorter, respectively, for influenza vaccination than viral infection.27 Like infection, influenza vaccination during pregnancy has been reported to induce a transient increase in the levels of a number of proinflammatory cytokines, including interleukin 6, tumor necrosis factor α, and C - reactive protein.27 - 30 Studies on mice found an association between high interleukin - 6 levels during pregnancy and abnormal behavior and brain structure.19 However, in epidemiological studies, associations between maternal cytokine levels and ASD have been mixed.

Mutations in RNAse L that impair the apoptotic response to viral infection were postulated to reflect enhanced susceptibility to infection by XMRV and suggested a potential role for the virus in carcinogenesis [5], [6], [7], [8].

This brain inflammation is caused by the release of cytokines, chemical messengers in the body that trigger an immune response, similar to a viral infection.

As both bacterial and viral genomes were detected in the present brain specimens, we examined host genes known to participate in responses to infections.

Autoimmune conditions are often a result of genetic weaknesses being triggered by an autoimmune system response to toxins, food proteins, or chronic viral, bacterial, and yeast infections, which creates a cascade of inflammation in the body.

HSF4 belongs to a family of heat shock transcription factors that regulate the expression of heat shock proteins in response to different stresses, such as oxidants, heavy metals, elevated temperatures and bacterial and viral infections [96].

This new data will provide insight into the cat's immune response to infectious diseases and will help detect breaches in protection against viral infections.