Sentences with phrase «in rhabdomyosarcoma»
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma.
http://ccri.uthscsa.edu/
«A so - called «muscle» cancer is not really a muscle cancer: Pinpointing the cell type that turns malignant in rhabdomyosarcoma opens the path for better treatments.»
Not exact matches
No RAS pathway mutations were found in alveolar rhabdomyosarcoma.
«Studies like the current one involving rhabdomyosarcoma are giving us a close - up look at the way cancer evolves in response to treatment,» said study co-author Richard K. Wilson, Ph.D., director of The Genome Institute at Washington University School of Medicine in St. Louis, where scientists have extensive expertise analyzing tumor recurrence using whole - genome sequencing.
Drugs that enhance a process called oxidative stress were found to kill rhabdomyosarcoma tumor cells growing in the laboratory and possibly bolstered the effectiveness of chemotherapy against this aggressive tumor of muscle and other soft tissue.
«Overall, survival for patients with recurrent rhabdomyosarcoma is just 17 percent, and until now nothing was known about how tumors evolve in response to therapy,» said corresponding author Michael Dyer, Ph.D., a member of the St. Jude Department of Developmental Neurobiology and a Howard Hughes Medical Institute Investigator.
About 350 new cases of rhabdomyosarcoma are identified each year in the U.S., making it the most common soft tissue tumor in children.
The findings may also lead to drugs to prevent rhabdomyosarcoma in children with a genetic predisposition to the cancer, Hatley said.
A rhabdomyosarcoma can occur in many places in the body, most commonly around the structures of the head and neck, within the urogenital tract, and in the arms or legs.
In 2001, doctors diagnosed then - four - year - old Jimmy Mohan with rhabdomyosarcoma, an aggressive form of childhood cancer.
«Moody also forged how rhabdomyosarcoma is managed in kids, and not just radiation therapy but how radiation is intertwined with chemotherapy.
«The way we manage children with rhabdomyosarcoma today is based on what he did through all those years of tireless work in the Pediatric Oncology Group.
The study focused on embryonal rhabdomyosarcoma caused by mutations in the Sonic Hedgehog signaling pathway and used a mouse model developed in Hatley's laboratory.
In addition to research on rhabdomyosarcoma, the Ignatius laboratory has also generated new syngeneic zebrafish models of aggressive Malignant Nerve Sheath Tumors and hemangiosarcomas for which there are no effective treatments.
In vivo imaging of tumor - propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcomIn vivo imaging of tumor - propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcomin embryonal rhabdomyosarcoma.
Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma.
As noted in Part I of this article, γ - tocopherol is preferentially metabolized into γ - CEHC, and the latter compound has been observed to exert much stronger anti-proliferative activity than α - CEHC in prostate cancer cells and rhabdomyosarcoma cells.
In another case a 4 - month old dog was affected with embryonal rhabdomyosarcoma of the trachea.
There are various types of bladder tumors like squamous cell carcinoma (arise in the epithelial cells), adenocarcinoma (arise in the glandular epithelium), undifferentiated carcinoma, rhabdomyosarcoma (tumor of the striated muscle - form of fibers combined into parallel fibers like the skeletal and the cardiac muscles), fibroma (tumors made of fibrous or connective tissue.
Pleomorphic rhabdomyosarcoma with pulmonary metastasis in a stranded Steller (northern) sea lion (Eumatopias jubatus).