Sentences with phrase «in rodent studies»

In rodent studies, over-exposure in the womb causes reproductive birth defects.

In rodent studies, TRF with an early eating period (eTRF) mitigates weight gain by increasing energy expenditure (EE).

Accumulating data suggests that IER may also activate hormesis, and there has been some suggestion that it is thestress associated with fasting, or the alternating periods of anabolism and catabolism, rather than an overall ER is responsible.15, 105 IER (100 % ER / alternate days) in rodent studies has been shown to up - regulate the expression ofanti - oxidative 20, 105, anti-apoptotic 20, 21 and pro-angiogenic 21 factors.

After three weeks of IER however, a separate study noted a reduction in fat - mass, which suggests that unlike in the rodent studies mentioned previously, humans may be unable to fully compensate for energy deficits incurred on fast days with increasing durations.

In rodent studies, calorie restriction can extend life span by 20 % to 80 %.

Changes in muscle repair with aging were determined by injecting the old mice and young mice (neither group exercised) with snake venom commonly used to induce muscle injury in rodent studies.

The specifics have yet to be ironed out, but the Amgen team has uncovered a few clues in their rodent studies: They found treated animals had increased activation of certain neurons in the brain that detect blood sugar, and this may have helped them sense when it was time to stop eating.

And although many of the initial animal studies used mRNAs with pseudouridine, Moderna's new chemistry was already starting to outperform that first generation in rodent studies.

In another rodent study published this week in Science Translational Medicine a group of researchers from multiple institutions identified a pathway responsible for the formation of amyloid plaques.

Not exact matches

The study, just published in Science, showed that the creation of what the researchers are calling microtumors can help predict drug effectiveness in cancer patients better than the current standard method of testing the drugs on rodents.

A native of Alice, Texas, Allison had somehow ended up in crunchy Northern California — at UC - Berkeley, no less — studying the immune systems of little white rodents.

One study found that the CRH system and HPA axis got stuck in overdrive in adult rodents that had been separated from their mothers too early in life.

Neuroscientists have over the past decade uncovered evidence, both in rodent and human studies, that parental caregiving, especially in moments of stress, affects children's development not only on the level of hormones and brain chemicals, but even more deeply, on the level of gene expression.

With the support of her rodent - tolerant family, she studied the effects of varying thyroid hormone levels on the physical characteristics of a small rat colony she housed in her living room.

In the new study, rodents were trained to press a lever to receive a dose of cocaine.

«In this study we provide a novel mechanism to explain this biological phenomenon in rodents, and we are now examining whether this mechanism translates to humans.&raquIn this study we provide a novel mechanism to explain this biological phenomenon in rodents, and we are now examining whether this mechanism translates to humans.&raquin rodents, and we are now examining whether this mechanism translates to humans.»

In other studies, Sonntag's group has shown that infusing IGF - 1 into the brain improves memory and learning in elderly rodentIn other studies, Sonntag's group has shown that infusing IGF - 1 into the brain improves memory and learning in elderly rodentin elderly rodents.

Despite promising results from past studies in rodents and nonhuman primates, testing the antisense strategy in people carried big unknowns.

In one study, the object was to determine whether phytic acid could retard cancer in rodentIn one study, the object was to determine whether phytic acid could retard cancer in rodentin rodents.

Rattus detentus, a Rodent of Unusual Size: On Manus Island, separated from New Guinea by about 100 miles of ocean, researchers found one of the largest rats known from the Melanesian archipelago, a particularly rich region for rat diversity, according to the April study in the Journal of Mammalogy.

Studies by other scientists later documented the same phenomenon in other rodents as well as in primates and people.

In a similar heart study, rodents dosed with phytic acid registered a drop in serum cholesterol of 32 percent and a decrease in triglycerides of 64 percenIn a similar heart study, rodents dosed with phytic acid registered a drop in serum cholesterol of 32 percent and a decrease in triglycerides of 64 percenin serum cholesterol of 32 percent and a decrease in triglycerides of 64 percenin triglycerides of 64 percent.

In a study appearing in the journal Integrative Biology, the researchers used this technology to identify materials that can efficiently deliver RNA to zebrafish and also to rodentIn a study appearing in the journal Integrative Biology, the researchers used this technology to identify materials that can efficiently deliver RNA to zebrafish and also to rodentin the journal Integrative Biology, the researchers used this technology to identify materials that can efficiently deliver RNA to zebrafish and also to rodents.

The study wasn't about designing a new way of testing animal behavior, either; the same test has been used in rodents.

Furthermore, animal studies suggest that taste buds produce hormones that are important for glucose metabolism and that, in rodents, taste buds decrease in number with age.

Studies in rodents suggest that stress during pregnancy inhibits neural growth, while the children of women who lived in war zones during pregnancy have a higher risk of developing schizophrenia.

In particular, the study showed new protein synthesis in a specific sub-region of the prefrontal cortex known in rodents as the prelimbiIn particular, the study showed new protein synthesis in a specific sub-region of the prefrontal cortex known in rodents as the prelimbiin a specific sub-region of the prefrontal cortex known in rodents as the prelimbiin rodents as the prelimbic.

He proposed an independent study project in 1998, during his last year of his undergraduate work: studying hantaviruses within the rodent population in Montreal.

In a study published online October 10 in Nanomedicine the researchers report that the liquid controlled bleeding in rodents within 15 seconds in seven other wound types, including cuts to the spinal cord, liver [view video here] and femoral artery as well as skin punctureIn a study published online October 10 in Nanomedicine the researchers report that the liquid controlled bleeding in rodents within 15 seconds in seven other wound types, including cuts to the spinal cord, liver [view video here] and femoral artery as well as skin puncturein Nanomedicine the researchers report that the liquid controlled bleeding in rodents within 15 seconds in seven other wound types, including cuts to the spinal cord, liver [view video here] and femoral artery as well as skin puncturein rodents within 15 seconds in seven other wound types, including cuts to the spinal cord, liver [view video here] and femoral artery as well as skin puncturein seven other wound types, including cuts to the spinal cord, liver [view video here] and femoral artery as well as skin punctures.

The oldest studied rodent fauna in this work, which inhabited the Iberian Peninsula from twelve million years ago, progressively shifted north looking for humid environments to survive climate change that caused prominent dry and cold environments in central Iberia.

Perhaps most significantly, in a study led by Frances Champagne — then a graduate student in Meaney's lab, now an associate professor with her own lab at Columbia University in New York — they found that inattentive mothering in rodents causes methylation of the genes for estrogen receptors in the brain.

The study was done with rodent malaria, but the researchers, at Pennsylvania State University in University Park, expect the pattern to apply to human malaria and possibly to other mosquito - borne diseases such as dengue fever and West Nile virus.

The study used a proven rodent model of HO that mimics the injuries seen in combat casualties.

MASTER HUNTER Nerve cells in a mouse's amygdala send messages that help the rodent chase and kill prey such as crickets, a new study shows.

Scientists at the Barshop Institute for Longevity and Aging Studies, part of the School of Medicine at the UT Health Science Center at San Antonio, have found another secret of longevity in the tissues of the longest - lived rodent, the naked mole rat.

Studies of rodents have suggested that pregnancy results in greater resilience to stress.

After starting with these human observations, Palmer's team is now studying the same delay discounting - related genetic traits in rodent models.

While studying the inflammatory mechanisms underlying colitis in rodents, a team of researchers led by Dana Philpott and Thierry Mallevaey realized that their laboratory mice were more susceptible to developing the disease if their intestines were already infected with the protozoan Tritrichomonas muris.

Studies in rats tend to use much higher doses of THC than even a committed pothead would absorb, and rodent adolescence is just a couple of weeks long — nothing like ours.

A new study demonstrates just how cancer - resistant Spalax are, and suggests that the adaptations that help these rodents survive in low - oxygen environments also play a role in their longevity and cancer resistance.

Studies have shown that exercise can have both structural and cognitive benefits in rodent models of pathological conditions like Fetal Alcohol Spectrum Disorders (FASD) and Alzheimer's disease.

Studies in rodents and in human fetal beta cells have showed that the responses of very young beta cells to increases in blood glucose are blunted when compared to their more - mature counterparts.

In this study, the team, which included Dr. Meerim Nurbaeva and Miriam Eckstein in Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalinIn this study, the team, which included Dr. Meerim Nurbaeva and Miriam Eckstein in Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalinin Dr. Lacruz's lab, for the first time used freshly dissected enamel cells (ameloblasts) from rodent teeth to modulate physiological processes in order to understand the contribution of CRAC channels in enamel calcium signalinin order to understand the contribution of CRAC channels in enamel calcium signalinin enamel calcium signaling.

In a study published last fall, researchers showed that male prairie voles that had been separated from their female partners for four days — a much shorter amount of separation time than researchers had previously found to affect the voles» physiology — exhibited depressionlike behavior and had increased levels of corticosterone, the rodent equivalent of the human stress hormone cortisol.

Furthermore, a rodent study concurrently examined the effects of mid-puberty or adult alcohol exposure on voluntary alcohol consumption in later life by 20 male Wistar rats.

Astronauts will use the device to study the effects on rodents of extended periods of time spent in microgravity.

«Studies in rodents have shown that artificially manipulating VTA activity strongly influences behavior, and our work has bridged the gap between rodent and primate.»

Dr Kristensen recommends that an inter-disciplinary approach be taken to address this, «by combining epidemiological data from human studies with more experimental research on models, such as rodents, it may be possible to firmly establish this link and determine how it happens, so that pregnant women in pain can be successfully treated, without risk to their unborn children.»

In these reviewed studies, rodents given paracetamol during pregnancy, at doses equivalent to those that a pregnant woman may take for pain relief, produced female offspring with fewer eggs.

In the current study, researchers at the University of North Carolina at Chapel Hill and Stanford University used rodent models to examine the role of this neurotransmitter in dynamically tracking specific elements of value - based decision makinIn the current study, researchers at the University of North Carolina at Chapel Hill and Stanford University used rodent models to examine the role of this neurotransmitter in dynamically tracking specific elements of value - based decision makinin dynamically tracking specific elements of value - based decision making.