Conclusion: Supplementation with whey protein, essential amino acids, and vitamin D, in conjunction with age - appropriate exercise, not only boosts fat - free mass and strength but also enhances other aspects that contribute to well - being
in sarcopenic elderly.
This was a randomized, controlled, double - blind, parallel - group superiority clinical trial to compare the efficacy of whey protein, essential amino acid, and vitamin D supplementation or placebo in improving FFM or strength
in sarcopenic elderly people in a hospital and rehabilitation division.
Jolene: My graduate research was
in sarcopenic obesity, and how we actually prevent that, using amino acids, namely branched chain amino acids, so I love that you brought that up.
Not exact matches
The study authors point to a need for more well - designed studies assessing the impact of a combined exercise intervention and dietary intervention
in frail and
sarcopenic populations, and
in populations suffering from nutritional deficiency or at risk of malnutrition.
Thus, these data were insufficient to describe the adaptive changes
in autophagy - linked molecules within
sarcopenic muscle.
A twice daily dietary supplement for 13 weeks containing whey protein, leucine, and vitamin D (20 g whey protein, 3 g total leucine, and 800 IU vitamin D) was given to older (~ 78 years) primarily independent - living
sarcopenic adults and resulted
in improved chair — stand test time and showed a greater gain
in skeletal muscle mass than the control group (and these results were repeated
in other studies).
Design: A total of 130
sarcopenic elderly people (53 men and 77 women; mean age: 80.3 y) participated
in a 12 - wk randomized, double - blind, placebo - controlled supplementation trial.
Supplementation significantly improved RSMM and muscle strength and,
in fact, 68 % of
sarcopenic people became nonsarcopenic (19).
The substantial improvements
in RSMM and muscle strength
in the supplementation group improved the classification of 68 % of the elderly people
in that group from
sarcopenic to nonsarcopenic, but none of the participants
in the placebo group showed improvement (Fisher's exact test P < 0.001).
Effects of exercise and amino acid supplementation on body composition and physical function
in community - dwelling elderly Japanese
sarcopenic women: a randomized controlled trial
The majority of studies show that resistance exercise training must be carried out at high intensity to achieve substantial improvements
in muscle strength, but, for
sarcopenic people, high - intensity resistance training may not be realistic or practical.
This study found a significant beneficial effect of supplementation with whey protein, essential amino acids, and vitamin D compared with placebo
in elderly
sarcopenic adults participating
in controlled resistance training, with a gain of 1.7 kg
in FFM.
Protein supplementation combined with physical exercise, particularly resistance training, has yielded mixed results on body composition, muscle hypertrophy, strength, and physical function
in the elderly (6, 39, 42 — 47), even though most studies have focused on healthy older adults, with limited data from trials on
sarcopenic individuals,
in which nutritional but not specifically protein and amino acid supplementation was a focus (39).