Sentences with phrase «in schizophrenia»

He is recognized worldwide for his research in schizophrenia, bipolar disease and substance abuse.

They found that six of the categories included a high proportion of genes also implicated in schizophrenia; the genes in these six categories relate to energy metabolism.

It is still not clear what exactly causes the condition but researchers know that genetics has a significant role in schizophrenia development.

For instance, the social difficulties present in autism can resemble the social withdrawal seen in schizophrenia.

There is a critical need to test how family contextual factors impact outpatient consumer functioning in schizophrenia.

There is also evidence that social stress causes the brain to increase the production of dopamine (which is believed by researchers to be one of the key factors in schizophrenia).

Although treatments may be years away, identifying this potential molecular mechanism in schizophrenia provides a starting point.

Low performance in schizophrenia is linked to a lack of communication between the frontal and temporal regions, which become active during perspective - taking.

Although the 15 participants used the sprays for three weeks only, most reported measurable improvements in their symptoms in this the first trial to test oxytocin in schizophrenia.

The research effort he directs focuses on entirely new compounds that might slow the loss of brain cell connections, which may play a role in schizophrenia biology.

The company was trying it for cognitive problems in schizophrenia, and expanded into prevention.

Studies have shown similar effects in disorders such as depression, he says, but this is the first time it has been related directly to cognitive deficits found in schizophrenia.

Formal thought disorder in schizophrenia and bipolar disorder: A systematic review and meta - analysis.

Despite its importance for social interactions, little is known about empathy in schizophrenia.

This theoretical consistency is important, as it allows researchers to better focus future studies of brain connectivity in schizophrenia, by targeting the brain regions known to be affected.

The team will now monitor the monkeys for behaviour similar to that seen in schizophrenia.

The gene seems to be inherited from your father's side and affects the symmetry of the brain, a factor in schizophrenia.

A multicentre trial is currently underway, into whether the antibiotic minocycline, used for the treatment of acne, can be used to treat lack of enjoyment, social withdrawal, apathy and other so called negative symptoms in schizophrenia.

Without BDNF, the abnormal circuit development and brain network activity observed in schizophrenia patients results.

Electroconvulsive therapy in schizophrenia in China: a national survey Li Q, Su YA, Xiang YT, Shu L, Yu X, Ungvari GS, Seiner SJ, Chiu HFK, Ning YP, Wang GH, Zhang KR, Li T, Sun LZ, Shi JG, Chen XS, Mei QY, Li KQ, Si TM.

Dr. Robert Buchanan of the Maryland Psychiatric Research Center reported on several promising cognitive enhancers that are being clinically tested for their use in schizophrenia treatment.

Remarkably, two compounds that seem to exert these neuroprotective effects — both of them a focus of intense interest in schizophrenia research — aren't sophisticated drugs but simple compounds found in nature.

Similar weight gain trajectories also were observed in schizophrenia and bipolar disorder with slightly different start points.

This compares favourably with exercise programmes in healthy populations as well as in schizophrenia.

CONCLUSIONS: Together our findings suggest that disruption of KIF17, although rare, could result in a schizophrenia phenotype and emphasize the possible involvement of rare de novo mutations in this disorder.

«Low birth weight and preterm birth have been proposed as risk factors in schizophrenia in general, but past studies have not shown a large effect on risk,» says Dr. Bassett, who is also the Director of the Clinical Genetics Research Program at CAMH.

The paper describes a randomized controlled trial of targeting cognitive behavioural therapy (CBT) during prodromal or early signs of relapse in schizophrenia.

In layer 2, the density of cartridges arising from a transcriptionally - unique subset of chandelier cells containing calbindin was nearly 3-fold higher in the schizophrenia group.

Title: Modafinil combined with cognitive training: Pharmacological augmentation of cognitive training in schizophrenia Author: P. Michalopoulou et al..

Review: evidence for the effectiveness of attention training in schizophrenia is inconclusive

Publication: «Polypharmacy with antipsychotics, antidepressants or benzodiazepines and mortality in schizophrenia», Jari Tiihonen, Jaana T. Suokas, Jaana M. Suvisaari, Jari Haukka, Pasi Korhonen, Archives of General Psychiatry, online early publication 7 May 2012.

Evaluating depressive symptoms and their impact on outcome in schizophrenia applying the Calgary Depression Scale

«It allows us to probe executive processes like working memory, attention, planning — all those things are abnormal in schizophrenia.»

If anti-inflammatory drugs can be shown to work in schizophrenia, not only could they offer a safer option to treat the disorder, they might also be benign enough to protect those at ultra-high risk, says Wood.

«We may need to focus on drugs that modify chromatin in a way that decreases methylation,» Grayson says, to «turn on genes that are missing in the schizophrenia.»

After using clozapine - N - oxide to reduce MD activity in the mice by 30 % to 40 %, the team ran them through a series of tasks designed to assess cognitive skills that are often affected in schizophrenia.

Moreover, if there are weight differences in schizophrenia and bipolar disorder patients, we need to tailor prevention and intervention efforts specific to their needs.»

A rare exception is the gene known as disrupted in schizophrenia 1 (DISC1), in which some mutations have a strong effect.

Title: Alterations in spatial memory and anxiety in the MAM E17 rat model of hippocampal pathology in schizophrenia Author: F. Gastambide et al..

All along, deCODE has churned out papers on genetic variants commonly involved in schizophrenia, diabetes, cancer, and other diseases, mostly by comparing markers scattered along the genomes of healthy and sick people.

The latest research implicates both glutamate transmission and calcium channels in schizophrenia development.

«People tend to think that happiness in schizophrenia is an oxymoron,» said senior author Dilip V. Jeste, MD, Distinguished Professor of Psychiatry and Neurosciences.

«New findings reverse hypothesis of GABA neurodevelopment in schizophrenia.»

«The cortical folding pattern itself may not be so important, but the disturbances in connections between brain regions implicated by the changes in cortical folding could provide critical clues to deficits in the integrity of brain circuits that contribute to symptoms and functional impairment in schizophrenia,» commented Dr. John Krystal, Editor of Biological Psychiatry.

Studies like these will provide the proof - of - concept for targeting the immune system in schizophrenia.»

Cognitive deficits in schizophrenia have recently been ascribed to impaired representation and use of cognitive context.

An Emotional Training program «Mind Reading» developed by Researcher Simon Baron - Cohen is software designed for autistic children, but being used in schizophrenia research and possibly of value to children at high risk of schizophrenia (i.e. a child with close family relatives who have had schizophrenia).