These factors for me have resulted
in a slow progression to this period where we have dropped away further in the league and have key players with 1 year left seemingly holding us over a barrel and also it seems far from convinced of where the club is going.
At what stage will tau - directed therapies be effective
in slowing progression of tau pathology?
Therefore, should Drs. Doyle, Campbell, and O'Neill demonstrate that to block TLR2, or any of its downstream signaling molecules, would be beneficial
in slowing the progression of AMD, they would anticipate that drug inhibitors of the pathway are likely to already exist and could be rapidly directed to clinical trials for AMD.
Studies suggest that the earlier a person with Alzheimer's disease is treated with anti-dementia medications, the more likely the medication will be effective
in slowing the progression of the disease.
Furthermore, turmeric is a strong neuroprotective that has shown promise
in slowing the progression of neurological diseases like Alzheimer's and depression.
The medication shows promise
in slowing the progression of the disease.
Acupuncture and Chinese herbal therapy can be extremely beneficial
in slowing the progression of degenerative joint disease and helping to eliminate some of the associated aches and pains.
In addition to a fresh food diet, two supplements — aminocaproic acid and N - acetylcysteine, also called NAC — have proved beneficial (and very much so in some cases)
in slowing the progression of the disease.
I spent most of a month engrossed
in a slow progression through the world of Dark Souls III, fervently celebrating when I manage to defeat a boss or pass an area that claimed my life 100 times over.
Not exact matches
Lilly had spent 15 years developing the drug and many experts believed it would be first to the gate
in securing an FDA approval for
slowing Alzheimer's
progression.
That delay followed the failure of a trial
in November of Lilly's experimental Alzheimer's treatment solanezumab, which the company had hoped would be the first medicine approved to
slow progression of the disease.
For example, Eli Lilly & Co. (NYSE: LLY) has a phase 3 study of solanezumab under way
in mild to moderate Alzheimer's disease patients that may
slow disease
progression by breaking up amyloid plaque buildups thought to be a major cause of the disease.
He contributes to other large - scale clinical trials including SAVE (evaluating whether treatment of obstructive sleep apnoea with continuous positive airways pressure can reduce the incidence of serious CV events
in patients with established CVD), and CREDENCE, a randomised, double - blind, placebo - controlled trial assessing whether canagliflozin can
slow the
progression of diabetic nephropathy
in patients with type 2 diabetes.
Rumors are we are looking at a sporting director, again I feel it is
slow progression for Arsenal FC but it is a step
in the right direction, is it not?
If you look at the players who have been not performing as well as they should then you look at the signings then you will see Arsenal FC slowly rebuilding, I would like it done faster like a lot of Arsenal fans but
slow progression is happening... As I said, I am not happy with how
slow it is but Arsenal FC could do more if they had the people
in who could focus on those aspects.
Behind him
in the pecking order, Martin Kelly has shown excellent promise as a backup — even being linked with a first England call up — and to sign a 29 year - old would surely
slow his
progression.
His
progression was fairly
slow and steady
in truth - he was never a phenom, unlike most of the others on this list.
The Welshman has shown on a number of occasions that he has the ability to play at the highest level, but numerous injuries have stunted and
slowed his
progression over the years, and there are always worries that we could lose him to injury at any point
in the season.
How the pie -
in - the - sky expectations for the Timberwolves» young core has warped our ability to appreciate their recent success and
slower progression.
You'll hear and read many impressive things
in the coming days, weeks, months and perhaps even years about the tie, but what it showed me was that Liverpool's natural
progression under Jurgen Klopp is under no signs of
slowing down.
I have a rare genetic disease (only 500
in the U.S.) and during pregnancy I had to stop taking the only medication I have to
slow down the
progression.
Antiretroviral drugs that can
slow or stop the
progression of HIV infection while limiting HIV transmission could be a game changer
in the worldwide HIV epidemic.
The new study, called FOR - DMD (Finding the Optimum Regimen of Corticosteroids for Duchenne Muscular Dystrophy), will determine whether daily steroid treatment or an alternative regime is more effective
in slowing the disease
progression and managing side effects.
Still, researchers are intrigued by the possibility that cells may use these clearance mechanisms to propagate misfolded proteins throughout the brain —
in which case targeting the mechanisms could conceivably
slow disease
progression.
«While many people become discouraged about Alzheimer's disease because they feel there's little they can do to protect against it, these results suggest that engaging
in moderate physical activity may
slow down the
progression of the disease.»
Next up: a larger trial
in hundreds of patients to see if lowering mutant Htt protein
slows progression of the disease, then a trial
in healthy people who carry the mutant HTT gene to see if antisense treatments could prevent Huntington's altogether.
«We found that healthy food stores within one mile of their home was the only significant factor that reduced or
slowed the
progression of calcium buildup
in coronary arteries,» said Ella August, Ph.D., co-lead author who initiated the study and clinical assistant professor of epidemiology at the University of Michigan
in Ann Arbor.
In addition to suggesting that creatine could slow the progression of HD, these results also imply that neuroimaging may provide a useful biomarker of disease modification in studies of other potential treatment
In addition to suggesting that creatine could
slow the
progression of HD, these results also imply that neuroimaging may provide a useful biomarker of disease modification
in studies of other potential treatment
in studies of other potential treatments.
A report on the study, published
in the September issue of Neurobiology of Disease, also suggest that finding ways to prevent the loss of serotonin or introducing a substitute neurotransmitter could
slow or stop the
progression of Alzheimer's disease and perhaps other dementias.
«Now that we have more evidence that serotonin is a chemical that appears affected early
in cognitive decline, we suspect that increasing serotonin function
in the brain could prevent memory loss from getting worse and
slow disease
progression,» says Gwenn Smith, Ph.D., professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine and director of geriatric psychiatry and neuropsychiatry at Johns Hopkins University School of Medicine.
A few drugs have shown promise
in cell culture or animal models, but clinical trials
in humans are time consuming because of the
slow onset and
progression of the disorder's clinical symptoms.
A drug which has already been
in use for decades to treat liver disease could be an effective treatment to
slow down
progression of Parkinson's disease, scientists from the University of Sheffield have discovered.
Study results suggest that pharmacological action on these epigenetic alterations may be helpful
in slowing disease
progression.
«While much more research is needed, it is exciting to consider that pharmacological intervention
in these cellular processes might help
slow or even prevent disease
progression.»
Following up on these promising results, they decided to explore whether the drug SR8278 could
slow the
progression of muscular dystrophy
in an animal model.
«Scientists
slow progression of fatal form of muscular dystrophy: Hope lies
in nuclear receptor that regulates muscle.»
Two main risk factors for the
progression and worsening of pain and decreased
in function capacity are increased body mass,
in particular fat mass and
slower walking speeds.
In the end, the identification of microbial species or metabolites that are altered in Parkinson's disease may serve as disease biomarkers or even drug targets, and interventions that correct microbial imbalances may provide safe and effective treatments to slow or halt the progression of often debilitating motor symptom
In the end, the identification of microbial species or metabolites that are altered
in Parkinson's disease may serve as disease biomarkers or even drug targets, and interventions that correct microbial imbalances may provide safe and effective treatments to slow or halt the progression of often debilitating motor symptom
in Parkinson's disease may serve as disease biomarkers or even drug targets, and interventions that correct microbial imbalances may provide safe and effective treatments to
slow or halt the
progression of often debilitating motor symptoms.
The studies not only point to the future possibility of specific microRNAs as a treatment for colorectal cancer, but also to the importance of external metabolic events conducted outside the cancer cell
in the
progression of the disease — factors that could someday be targeted to help
slow metastasis, or even block it entirely.
Meditation may boost the immune response, protect against a relapse
in major depression, soothe skin conditions and even
slow the
progression of HIV
«We have identified a pathway
in microglia that may be targeted to ultimately
slow disease
progression in ALS and are exploring potential therapeutic strategies and may have broader implications for diseases such as Alzheimer's and Parkinson's Disease amongst others.»
In patients with chronic kidney disease who are not on dialysis, ACEIs and ARBs
slow the
progression of diabetic nephropathy and reduce cardiovascular risk.
Inhibiting NF - ƘB
in microglia
in mice
slowed disease
progression by 47 percent, says Brian Kaspar, MD, a principal investigator
in the Center for Gene Therapy at Nationwide Children's and senior author of the new study.
The vaccine
slowed the
progression of prion disease
in the remaining 70 % of the experimental mice, allowing them to live longer than control mice, which did not receive the vaccine and died within about 200 days following infection.
«This study also highlights the potential use of this anti-estrogen or miRNA
in patients with recurrent prostate cancer, for whom there is no treatment, and raises the possibility of using anti-estrogen or miRNA treatments
in preventing or
slowing progression for primary prostate cancer.»
A test for the early stages of the condition would be helpful
in efforts to develop drugs that can
slow its
progression.
According to a 2011 study published
in the New England Journal of Medicine, sirolimus
in selected patients
slowed the
progression of the disease and was associated with a reduction
in symptoms and improved quality of life.
Betanin, a substance found
in beets, could eventually help
slow the
progression of Alzheimer's disease.
A landmark clinical study
in The Lancet provides convincing evidence that a frequently overlooked therapy for genetically - caused emphysema is effective and
slows the
progression of lung disease.
In humans, the oil lowers VLCFA levels by slowing their synthesis, but it didn't slow down disease progression in clinical trial
In humans, the oil lowers VLCFA levels by
slowing their synthesis, but it didn't
slow down disease
progression in clinical trial
in clinical trials.