Sentences with phrase «in spatial learning»

They had less white and cortical gray matter, and smaller - sized hippocampi and amygdale — brain structures that play a key role in spatial learning, memory consolidation, stress reactivity, and the processing of emotion.

In an animal model, treadmill exercise improved symptoms of hyperactivity disorder, including an improvement in spatial learning memory (Kim et al. 2011).

A large body of evidence indicates that theta rhythm is likely involved in spatial learning and navigation (Buzsáki, 2005).

Harding, a medicinal chemist, and Wright, a neuroscientist, have been working on their compound since 1992, when they started looking at the impact of the peptide angiotensin IV on the hippocampus, a brain region involved in spatial learning and short - term memory.

Although the behavior of the mutant mice seemed mostly normal, further testing showed that they had deficiencies in spatial learning, confirming the enzyme's key role in that process.

First, the Morris maze can detect similar deficits in spatial learning and memory across species.

These developmental defects in the wiring of neural circuits cause very selective alterations in spatial learning and memory in adult mice.

«The pattern of activity in a brain region involved in spatial learning in the virtual world is completely different than when it processes activity in the real world,» said Mayank Mehta, a UCLA professor of physics, neurology and neurobiology in the UCLA College and the study's senior author.

Not exact matches

You may think it's just fun for her, and even get frustrated with the inevitable messes that your 19 - month - old's explorations create, but she's learning about perception and spatial relationships, concepts that will be important in a few years when she's introduced to math.

- strengthening the upper body and core muscles for other gross motor tasks - strengthening the upper body and core muscles to create a stable base for fine motor skills - developing stability in the bones of the shoulder joint (the ball and socket joints of the shoulders and hips are shallow and unstable at birth but are molded into stronger, more stable joints through weight - bearing)- visual development to quickly shift focus from near to far - hand - eye - coordination - providing plentiful early opportunities for motor planning (movement problem - solving)- refining balance - integrating the movement (vestibular), pressure & stretch (proprioceptive), visual and touch (tactile) sensory systems - learning to coordinate movements where two sides of the body are doing different movements - learning to coordinate upper body and lower body movements - developing body awareness and spatial awareness - fostering independence

Know that important language learning and spatial skills are being developed in an age - appropriate way.

Two new studies show how spatial parts of the brain are already functioning in infancy, revealing that not everything we understand about our surroundings is learned

As part of the limbic system, it plays an important role in memory processing and spatial cognition, including how mammals learn to understand and navigate their environment.

This brain region plays a critical role in learning new information, forming spatial memories and storing short - term memories as long - term ones.

The hippocampus — a region crucially involved in forming «episodic» memories (event recall) and spatial memory (for physical navigation)-- is especially affected by aging, with accompanying declines in the ability to learn and remember; it also deteriorates early on when afflicted by Alzheimer's.

Previous studies focusing on spatial - reward associative learning in foraging animals have assumed that foraging efficiency increases as the forager learns the locations of greater rewards.

According to McQuillan, a Ph.D. candidate in evolutionary biology at Lehigh and lead author of the study, the northern Black - capped Chickadee is a model species for studying spatial memory and learning, traits that are key to scatter - hoarders» survival.

For example, EEGs indicate that sleeping rats replay the running of a maze in a brain region devoted to spatial learning.

For instance, studies in mice have revealed that running enhances spatial learning.

«By refining the spatial pattern of mass loss in the world's second largest — and most unstable — ice sheet, and learning how that pattern has evolved, we are steadily increasing our understanding of ice loss processes, which will lead to better - informed projections of sea level rise.»

«My lab works on the neural bases of learning and memory,» says Pozzo - Miller, «so we decided to test if LM22A - 4 was able to improve spatial discrimination deficits by enhancing synaptic plasticity in the hippocampus, the brain region responsible for spatial learning and memory.»

In a 2014 study in rats, researchers at the University of California found that the neurons in a brain region associated with spatial learning behaved completely differently in virtual environments compared to in real ones, with more than half of the neurons shutting down while in VIn a 2014 study in rats, researchers at the University of California found that the neurons in a brain region associated with spatial learning behaved completely differently in virtual environments compared to in real ones, with more than half of the neurons shutting down while in Vin rats, researchers at the University of California found that the neurons in a brain region associated with spatial learning behaved completely differently in virtual environments compared to in real ones, with more than half of the neurons shutting down while in Vin a brain region associated with spatial learning behaved completely differently in virtual environments compared to in real ones, with more than half of the neurons shutting down while in Vin virtual environments compared to in real ones, with more than half of the neurons shutting down while in Vin real ones, with more than half of the neurons shutting down while in Vin VR.

Co-author Dr Lisa Leaver of the University of Exeter added: «We predicted that squirrels would be quick to learn this task because learning spatial arrays is crucial for them in order to recover their food caches in the winter months.

In the future, the researchers are interested in examining how the neural substrates of social and spatial learning differ in mouse models of autisIn the future, the researchers are interested in examining how the neural substrates of social and spatial learning differ in mouse models of autisin examining how the neural substrates of social and spatial learning differ in mouse models of autisin mouse models of autism.

Witten and her research team performed optogenetic experiments with the mice to isolate precisely which circuits of the brain are involved in social - spatial learning.

«Using this combined approach, we were able to reduce the levels of amyloid - beta, but, importantly, restored spatial learning and memory to the level observed in healthy mice,» Jankowsky said.

Here, we examined the extent to which performance in the Morris water maze — the most frequently used behavioral assay of spatial learning and memory in rodents — translates to humans.

A deficit in procedural learning can alter performance in the hidden - target task and confound the interpretation of spatial memory.

Direct hippocampal stimulation in six subjects had no effect on their performance of the spatial learning tasks, as compared with no stimulation, with respect to both latency (z = 0.52, P = 0.69)(Figure 2B) and excess path length (z = − 0.52, P = 0.69)(Figure 2D).

Our results show that spatial learning in humans can be enhanced by electrical stimulation of the entorhinal region, a specific site within the medial temporal lobe and the chief gateway into the hippocampus.

The subjects completed a spatial learning task that consisted of navigation through a virtual environment to deliver passengers to stores (Fig. 1 in the Supplementary Appendix).

Analysis of the distance, latency, and cumulative search error (CSE) rank - summary scores revealed that MCI - AD patients and hAPP mice were significantly impaired in this task (Table 1 and Figure 1, B — D and F — I), consistent with a deficit in hippocampus - dependent spatial learning.

In a test of spatial learning and memory, the mice with extra klotho performed twice as well.

Then, the team inserted the organoids into cavities made in mice's retrosplenial cortex — a region critical for movement and spatial learning.

A High Fructose Diet Does Not Affect Amphetamine Self - Administration or Spatial Water Maze Learning and Memory in Female Rats.

In the AD reversal treatment strategy described here, J147 significantly improved several different aspects of memory affected in AD, including spatial memory, a disinhibition phenotype and hippocampal dependent associative learning (Figure 1In the AD reversal treatment strategy described here, J147 significantly improved several different aspects of memory affected in AD, including spatial memory, a disinhibition phenotype and hippocampal dependent associative learning (Figure 1in AD, including spatial memory, a disinhibition phenotype and hippocampal dependent associative learning (Figure 1).

They have spatial learning and memory defects as assessed in the Morris water maze and the radial arm maze, show developmental delay in sensorimotor milestones, and exhibit locomotor hyperactivity, lack of behavioral inhibition, and stereotypic behavior.

Spatial learning ability of the threespine stickleback (Gasterosteus aculeatus) in relation to inferred ecology and ancestry.

The dentate gyrus, part of the hippocampus, is involved in learning, episodic memory formation and spatial coding.

Both assessments test spatial learning and require proper activation of the hippocampus, a brain structure that is one of the regions affected earliest in Alzheimer's disease.

The idea that the activity of a place cell is predictive and can be modified by learning and the behavior of other animals may make it easier to conceptualize an all - encompassing framework that ties together the hippocampus» role in spatial navigation with its well - established role in learning and memory formation.

Changes in the time it takes the rodent to find the platform in a series of successive trials can be used as a measure of spatial learning and memory.

Discovered that the persistent sodium current, INaP, paradoxically amplifies afterhyperpolarizations and reduces the frequency (f / I) gain, and strongly modulates spike timing (Vervaeke et al., Neuron 2006); that Kv7 / M / KCNQ - type K + channels but not SK channels are essential for excitability control in hippocampal neurons (Gu et al., J Physiol, 2005); that Kv7 / M / KCNQ - type K + channels are essential for spatial learning and prevention of epilepsy (Nature Neuroscience 8: 51 - 60, 2005), that KCa1 / BK - type K + channels are essential for cerebellar learning and motor control (Proc Natl Acad Sci USA 101: 0474 - 8, 2004), the role of postsynaptic voltage-gated K + channels in regulation of synaptic plasticity (LTP) and integration (Proc Natl Acad Sci USA 99:10144, 2002); that Kv7 / M / KCNQ - type K + channels are essential for intrinsic theta resonance in hippocampal neurons (J Physiol 545:783, 2002).

http://onlinelibrary.wiley.com/doi/10.1002/asia.201600259/full Subcutaneous administration of cyclodextrin significantly improved spatial learning and memory deficits in Alzheimer disease mice model doi: 10.1084 / jem.20121239.

In learning about how this method works — its strengths and its weaknesses — I understood that the patterns it produces could reflect spatial structure in population datIn learning about how this method works — its strengths and its weaknesses — I understood that the patterns it produces could reflect spatial structure in population datin population data.

In monkeys, deficiency of male hormones impairs the development of spatial perception (which, in humans, is normally more acute in men than in women), of learning ability and of visual discrimination tasks (such as would be required for readingIn monkeys, deficiency of male hormones impairs the development of spatial perception (which, in humans, is normally more acute in men than in women), of learning ability and of visual discrimination tasks (such as would be required for readingin humans, is normally more acute in men than in women), of learning ability and of visual discrimination tasks (such as would be required for readingin men than in women), of learning ability and of visual discrimination tasks (such as would be required for readingin women), of learning ability and of visual discrimination tasks (such as would be required for reading.)

In monkeys, deficiency of male hormones impairs learning and the ability to perform visual discrimination tasks - such as would be required for reading - and retards the development of spatial perception, which is normally more acute in men than in womeIn monkeys, deficiency of male hormones impairs learning and the ability to perform visual discrimination tasks - such as would be required for reading - and retards the development of spatial perception, which is normally more acute in men than in womein men than in womein women.

This reduces brain inflammation and restores spatial learning and coordination in rats (R).

That means I need to find ways to increase BDNF more than in someone with the normal gene in order to preserve my cognitive function, memory, and emotional regulation.8 Mu, J.S., et al. «Deprivation of Endogenous Brain - Derived Neurotrophic Factor Results in Impairment of Spatial Learning and Memory in Adult... continue 9Cirulli, F., et al. «Intrahippocampal Administration of BDNF in Adult Rats Affects Short - term Behavioral Plasticity in the Morris Water Maze and... continue

Mu, J.S., et al. «Deprivation of Endogenous Brain - Derived Neurotrophic Factor Results in Impairment of Spatial Learning and Memory in Adult Rats,» Brain Research 835 (1999): 259 - 265