They demonstrated that this region plays a
role in spatial memory, which was not significantly impaired in the older subjects.
The picture superiority effect is also
present in spatial memory, where locations of items and photographs were remembered better than locations of words.
The signals processed by these neurons are carried to distinct regions in the mushroom body (
involved in spatial memory formation), suggesting that the spatial information about pheromones are maintained from the surface of the antenna up to the mushroom body.
Pathological hallmarks of AD, including plaques and loss of synaptic markers, are readily apparent at nine months of age in huAPP / PS1 mice along with clear
deficits in spatial memory when compared to wild type controls [7, 10, 11, 31].
«But what we're seeing in these mice is that the balance between LTP and LTD is upset, and that disturbance may lead to the
problems in spatial memory acquisition.»
One explanation is that the plant sterol diet increased formation of reactive oxygen species in the hippocampus, whereas the Fortasyn diet, which yielded the best
results in the spatial memory task, tended to have an opposite effect.
Both J147 and the combination of J147 + donepezil rescued this deficit
in spatial memory created by scopolamine to a similar extent, but donepezil alone failed to rescue the deficit (Figure 4B).
The entorhinal cortex is one of the first areas to be affected in AD and is the main connection between the hippocampus and neocortex playing an important role in spatial memory [82].
Title:
Alterations in spatial memory and anxiety in the MAM E17 rat model of hippocampal pathology in schizophrenia Author: F. Gastambide et al..
Finally, ripples are sharp and quick bursts of electrical energy, produced within the hippocampus, a brain component with an important
role in spatial memory.
Two parts of the brain are especially fecund: the dentate gyrus (a region involved
in spatial memory) and the olfactory bulb (which sits right above the nasal cavities).
The hippocampus is the key structure involved
in spatial memory (orientation) and episodic memory (autobiographical events) within the brain.