Sentences with phrase «in squamous»

A study carried out by the department of Dermatology, University of California in June of 2011 involving 830 people comparing various vitamins found that the group taking grape seed extract experience a 74 percent reduction in squamous cell carcinoma — a type of skin cancer.
Inecalcitol, an analog of 1,25 D 3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model system.
1) Lockwood W and Politi K (2014) MYCxing It Up with FGFR1 in Squamous Cell Lung Cancer.
We have shown that p53 and Notch inhibiting mutations, both of which are common in squamous cancers, imbalance cell fate in this way, generating large mutant clones.
Medical oncologist Alexander T. Pearson, MD, PhD cares for adults with head and neck cancers, especially squamous cell carcinoma, a common form of cancer that develops in the squamous cells that make up the middle and outer layer lining the mouth and throat.
The prevalence of itch was greatest in squamous cell carcinoma (46.6 percent), followed by basal cell carcinoma (31.9 percent) and melanoma (14.8 percent).

Not exact matches

Kelly, 58, was diagnosed with squamous cell carcinoma isolated to his upper jaw in June 2013.
«The object of this study was to examine the sentinel lymph node alone in women with squamous cell carcinoma of the vulva and evaluate their recurrence in the groin and any complication rates,» Dr. Moore explains.
In a head - to - head clinical trial comparing standard chemotherapy with the immunotherapy drug nivolumab, researchers found that people with squamous - non-small cell lung cancer who received nivolumab lived, on average, 3.2 months longer than those receiving chemotherapy.
Now a team of researchers has been able to identify accurately the sentinel node (SN) in head and neck squamous cell carcinoma (HNSCC) using a novel tracer; a challenging task because there are up to 150 different lymph nodes in the neck, and the differentiation of true SNs from secondary nodes is difficult.
«We'd like to extend this further to examine for driver genes in other types of lung cancer, such as squamous cell lung cancer.»
In the case of head and neck squamous cell carcinoma, for example, high stemness indices correlated with mutations in the gene NSDIn the case of head and neck squamous cell carcinoma, for example, high stemness indices correlated with mutations in the gene NSDin the gene NSD1.
Patients with epidermal growth factor receptor (EGFR) expressing advanced squamous non-small-cell lung cancer benefit most from necitumumab added to gemcitabine and cisplatin chemotherapy, according to a subgroup analysis from the SQUIRE trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.
The Ogretmen laboratory screened previously reported microarray data sets of several human tumor tissues (metastatic head and neck squamous cell carcinoma, melanoma, and renal cell carcinoma) and showed that, in these samples, only the levels of CerS4 were significantly decreased.
Basal and squamous cell carcinoma are the most common types of cancer in the United States and represent the vast majority of all cases of skin cancer; however, they rarely result in death or substantial morbidity, whereas melanoma skin cancer has notably higher mortality rates.
In the past decade, medical research has discovered direct links between tanning bed use and higher rates of the skin cancers basal cell carcinoma, squamous cell carcinoma and melanoma.
The risk of skin cancer increases the more hydrochlorothiazide you have taken throughout your lifetime, and the risk of squamous cell carcinoma was up to seven times greater for people who had taken hydrochlorothiazide in an amount corresponding to > 10 years» use.
In the past decade, medical research has discovered direct links between tanning bed use and higher rates of the skin cancers basal cell carcinoma, squamous cell carcinoma and melanoma, according to Dr. Thomas.
Hydrochlorothiazide increased the risk of basal cell carcinoma, which is the least serious type of skin cancer, as well as of squamous cell carcinoma, which is more aggressive and in some cases manages to spread to other parts of the body.
In September oncologists reported they sequenced deadly squamous cell lung cancer in 178 patientIn September oncologists reported they sequenced deadly squamous cell lung cancer in 178 patientin 178 patients.
That prospect looked even more remote when Martensen's doctors discovered that he had squamous small cell lung cancer, a less common form in which the cancer cells are scaly and thin.
Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS - variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.
In the new research, Prins and Liau used a technique called adoptive cell transfer, which involves extracting and growing immune cells outside of the body, then reprogramming them with a gene known as New York Esophageal Squamous Cell Carcinoma, or NY - ESO - 1.
It's also known to play a role in a form of leukemia, as well as liver cancer, squamous cell skin carcinomas, squamous cell cancers of the head and neck and other cancers.
A class of therapeutic drugs known as protein kinase inhibitors has in the past decade become a powerful weapon in the fight against various life - threatening diseases, including certain types of leukemia, lung cancer, kidney cancer and squamous cell cancer of the head and neck.
So the group set out to test whether selenium might reduce the chance of recurrence of basal cell or squamous cell carcinoma in people previously treated for skin cancer.
In a collaborative study, researchers from Chinese Academy of Medical Sciences and Peking Union Medical College, BGI, Shantou University Medical College and other institutions identified important alterations of tumor - associated genes and tumorigenic pathways in esophageal squamous cell cancer (ESCC), one of the leading cause of cancer death worldwidIn a collaborative study, researchers from Chinese Academy of Medical Sciences and Peking Union Medical College, BGI, Shantou University Medical College and other institutions identified important alterations of tumor - associated genes and tumorigenic pathways in esophageal squamous cell cancer (ESCC), one of the leading cause of cancer death worldwidin esophageal squamous cell cancer (ESCC), one of the leading cause of cancer death worldwide.
The FDA, in its warning letter to Meditherm, ordered the company to stop making broad claims about its cameras, pointing to a Web page that lists «76 specific conditions for which you say your device can be used... for example, lower motor neuron disease, neoplasias (melanoma, squamous cell, basal) and nutritional disease (alcoholism, diabetes).»
Changes in cell junctions induced by inhibition of epidermal growth factor receptor in oral squamous cell carcinoma cells.
14255: STAT3 Signaling During Chemo - Radiation for Squamous Cell Carcinoma of the Head and Neck 14340: A Phase II, Randomized, Open - Label, Multi-Center, Global Study of MEDI4736 Monotherapy, Tremelimumab Monotherapy, and MEDI4736 in Combination with Tremelimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) 14258: Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma.
(HealthDay)-- Most active smokers with head and neck squamous cell carcinoma (HNSCC) have made one or more quit attempts, according to a study published online April 12 in JAMA Otolaryngology - Head & Neck Surgery.
MicroRNA - 34a directly targets high - mobility group box 1 and inhibits the cancer cell proliferation, migration and invasion in cutaneous squamous cell carcinoma.
Identification of a human papillomavirus - associated oncogenic miRNA panel in human oropharyngeal squamous cell carcinoma validated by bioinformatics analysis of the Cancer Genome Atlas.
Neuropilin 1 Receptor Is Up - Regulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma.
Window - of - Opportunity Trial of Nivolumab and Tadalafil in Patients with Squamous Cell Carcinoma of the Head and Neck
Scholar - in - Training Awards in the amount of $ 1,000 for her submitted abstract entitled, «Activator protein 2 alpha (AP2α)- targeted methylation and silencing of relevant genes in head and neck squamous cell carcinoma (HNSCC) pathogenesis» to be presented at platform session at the 100th Annual Meeting of the American Association for Cancer Research, Denver, CO..
Interleukin - 8 as a modulator of response to bevacizumab in preclinical models of head and neck squamous cell carcinoma.
Desmosomal Component Expression in Normal, Dysplastic, and Oral Squamous Cell Carcinoma.
p16INK4a and p14ARF tumor suppressor genes are commonly inactivated in cutaneous squamous cell carcinoma.
Decreased plakophilin - 1 expression promotes increased motility in head and neck squamous cell carcinoma cells.
Clinico - Pathological Correlation of β - Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients.
Oct4 Mediates Tumor Initiating Properties in Oral Squamous Cell Carcinomas through the Regulation of Epithelial - Mesenchymal Transition.
HPV is associated with squamous cell cancers, which are common in HPV - related anal cancer, but not in colorectal cancers.
DDX3 was strongly immunolocalized in the nucleus and less intensively in the cytosol of squamous cells in normal skin, but the nuclear staining was lost or dramatically decreased in cutaneous SCC.
Additionally, an extensive loss of its nuclear localization was observed in cutaneous squamous cell carcinoma (SCC) compared with normal squamous cells.
Additionally, an alteration of subcellular localization from nuclei to cytoplasm was also observed in > 70 % of cutaneous squamous cell carcinoma samples.
Because DDX3 harbors a dominant nuclear localization in normal squamous cells and exerts a transactivation function on p21waf1 / cip1 promoter, presumably the inactivation of transcriptional modulation function of DDX3 through cytoplasmic mislocalization is relevant to the deregulation of cell growth in cancerous squamous cells.
We focus on squamous tissues, the skin epidermis and the lining of the oesophagus, using transgenic models, novel sequencing approaches, live imaging and single cell analysis to uncover key steps in cancer development, with aim of developing rational interventions to decrease cancer risk.
Gene Expression Differences in Normal Esophageal Mucosa Associated with Regression and Progression of Mild and Moderate Squamous Dysplasia in a High - Risk Chinese Population
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