Sentences with phrase «in subsets of patients at»

The nomogram also performed well in subsets of patients at the extremes of weight and renal function (Table 3).

Not exact matches

In a randomized, phase 2 multi-center clinical study, led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutationIn a randomized, phase 2 multi-center clinical study, led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutationin combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutations.

Although it is among the most highly metastatic of all cancers, multiple myeloma is driven to spread by only a subset of the myeloma cells within a patient's body, researchers at Dana - Farber Cancer Institute have found in a study presented at the annual meeting of the American Society of Hematology (ASH).

«We found that intensive doses of statins carry the potential for clearing up the lipid debris that can lead to vision impairment in a subset of patients with macular degeneration,» said Joan W. Miller, M.D., the Henry Willard Williams Professor and Chair of Ophthalmology at Harvard Medical School and Chief of Ophthalmology at Massachusetts Eye and Ear and Massachusetts General Hospital.

The study enrolled 100 patients with de novo coronary lesions 2.25 - 3.50 mm in diameter and length ≤ 27 mm in two 50 - patient cohorts for angiographic, intravascular ultrasound, and clinical assessment at nine or 24 months, with optical coherence tomography (OCT) performed in a subset of 30 patients at multiple time periods.

The rationale for an observational approach is to avoid the morbidity of lymphadenectomy (specifically to avoid the possibility of lymphedema) for two subsets of patients who never manifest isolated recurrence in the lymph node basin: those who have no melanoma remaining in the nodal basin and those who experience distant treatment failure at or before the time of nodal recurrence.

But that optimism, plus the availability of FDA - approved drugs with an HDAC inhibitory effect, has also prompted many families to find doctors who will prescribe these drugs, without knowing whether they work, or at what doses, or in which subset of patients.

Some of the earliest studies of cancer genomes in AML noted that, within a single patient, there were subsets of mutations present at lower allele frequencies, suggesting that they're not present in all cells.

This is an exciting finding as it suggests that the immune responses activated in at least this subset of PD patients resemble those driving autoimmune diseases like multiple sclerosis.

Would you think it is plausible that at least in a subset of patients the psychological symptoms develop as an outgrowth of the inability to properly store fat?

In a subset of 20 patients who participated in TACT, the levels of toxic metals were measured at baseline and again after receiving a 3 - gram dose of EDTA.14 After treatment, the largest increases of metals were with lead (3700 %) and cadmium (750 %In a subset of 20 patients who participated in TACT, the levels of toxic metals were measured at baseline and again after receiving a 3 - gram dose of EDTA.14 After treatment, the largest increases of metals were with lead (3700 %) and cadmium (750 %in TACT, the levels of toxic metals were measured at baseline and again after receiving a 3 - gram dose of EDTA.14 After treatment, the largest increases of metals were with lead (3700 %) and cadmium (750 %).

All of the case series studies showed improvements in clinical measures, which indicates that these outcomes can be obtained in the outpatient practice setting in at least a subset of adherent patients.