Sentences with phrase «in the clinical trials as»

Already, at least one related drug from AstraZeneca is being evaluated in clinical trials as a candidate for treating autistic behaviors.

With A3AR drugs demonstrating good safety profiles in clinical trials as anti-inflammatory and anti-cancer agents, Salvemini and colleagues are enthusiastic about the potential of these new drugs to treat chronic pain in patients.

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

A neuregulin - 1 treatment is not available on the market, though it is being explored in clinical trials as a potential treatment for chronic heart failure and Parkinson's disease.

It has broad implications for how we evaluate new drugs in clinical trials as well.»

The Clinical Islet Program does not have any immediate plans to follow this approach but may participate in clinical trials as they become available.

Now, we can be sure that we will have no disruption in the research or in the clinical trials as they progress.

These dual attributes improve the chances for success in clinical trials as a disease - modifying drug, and seems ideally suited for rapid progress through the new FDA guidelines for AD trials [126].

The exclusive, worldwide license, announced Sept. 14 by Mustang Bio, will allow a new type of CAR (chimeric antigen receptor) T - cell therapy to be tested in a clinical trial as a treatment for B - cell non-Hodgkin lymphomas.

There are three readily discernible components of value: 1) Net cash or the amount of cash left after liquidation of marketable securities and repayment of the LT debt and other liabilities, 2) The royalty revenue stream from the patented Customised Linker Technology (the PegIntron royalties) and 3) the intellectual property related to the four compounds currently in clinical trials as well as any other compounds in pre-clinical development.

Not exact matches

Then, they plan to get started with clinical trials in their journey toward FDA approval, starting with peanuts, but expanding out to the other top food allergies, such as soy, wheat, milk, and eggs.

The latest clinical trial outsourcing / drug development and manufacturing merger hit on Monday as scientific instrument giant Thermo Fisher announced it would buy drug ingredients maker Patheon for $ 5.2 billion ($ 7.2 billion is you count $ 2 billion in net debt).

As one of the world's premier experts in clinical trials, Don Berry, told me, «The standard clinical trial is pretty much the only thing in medicine that hasn't changed in the last 70 years.»

You can find the same types of long - running disagreements across the therapeutic board in clinical trials, as I wrote about years ago in an essay for the New York Times, entitled «Do Clinical Trials Workclinical trials, as I wrote about years ago in an essay for the New York Times, entitled «Do Clinical Trials Work?&trials, as I wrote about years ago in an essay for the New York Times, entitled «Do Clinical Trials WorkClinical Trials Work?&Trials Work?»

Just this month, as part of the first large - scale clinical trial of its kind, researchers working in rural India found that newborns who were given a synbiotic were at a substantially lower risk of developing sepsis, a potentially fatal condition characterized by severe infection.

Taking this drug daily has shown to offer more than 90 % (and as much as 99 %) effective protection against HIV in clinical trials, and certain New Zealand residents will soon be able to get a three - month supply for just $ 5 (oh, and that's five New Zealand dollars, which is about $ 3.64 in U.S. money).

So in 2016, HVMN — known as Nootrobox at the time — set out to prove itself by testing one of its supplements, a «cognitive enhancement» called SPRINT, against caffeine in a landmark clinical trial.

It had originally registered the clinical trial in a U.S. government database as «The Effects of SPRINT, a Combination of Natural Ingredients, on Cognition in Healthy Young Volunteer.»

«IBM and the FDA will explore the exchange of owner mediated data from several sources, such as Electronic Medical Records, clinical trials, genomic data, and health data from mobile devices, wearables and the «Internet of Things,»» said the company in a press release.

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

In fact, Amgen's Repatha and Sanofi's Praluent, the first of these types of treatments to win approval in the U.S., reduced LDL cholesterol by as much as 60 % in clinical trialIn fact, Amgen's Repatha and Sanofi's Praluent, the first of these types of treatments to win approval in the U.S., reduced LDL cholesterol by as much as 60 % in clinical trialin the U.S., reduced LDL cholesterol by as much as 60 % in clinical trialin clinical trials.

The new Alzheimer's framework may not be much of a surprise given numerous, high - profile, late - stage clinical trial failures in the field by companies like Eli Lilly and Merck, and the decision by other companies (such as Pfizer) to back away from the risk - prone field.

That could be key as more cutting - edge therapies try to find success in clinical trials.

Now that the barrier of editing genes in the hospital setting has been broken, these companies and more have pipelines of gene - editing innovation coming to a hospital near you in the next few years, as clinical trials are approved and new ways to cure formerly incurable diseases go mainstream in our lifetimes.

Early clinical trials indicate that restricting calorie intake seems to trigger similarly promising physical changes in people, which is why it's sometimes discussed as a potential anti-aging intervention.

As an exec at Shire (shpg), which with $ 6 billion in revenue is one of the smaller Big Pharmas, he spent months persuading leaders and commercial and supply - chain people to launch a clinical trial for the ADHD drug Vyvanse to treat binge eating.

As we explained in our ASCO primer, pharma giants like Merck (mrk) and Bristol - Myers Squibb (bmy) and biotechs like Juno (juno) and Kite Pharma (kite) had a lot to prove through their clinical trial updates on experimental immunotherapies.

Amarin's clinical development program for Vascepa includes a trial known as the REDUCE - IT cardiovascular outcomes study, an 8,175 - patient study commenced in 2011.

In fact, one of Marathon's clinical trials that the FDA used as part of its decision - making process was conducted more than 20 years ago, saving the firm plenty of study costs.

However, in very rare circumstances, Ionis Pharmaceuticals is able to make an experimental drug that we are developing available for patients outside of a traditional clinical trial under an expanded access protocol, sometimes referred to as a treatment protocol.

Athenex, which raised $ 68 million from a secondary stock offering during the quarter, finished the year with $ 51 million in cash and short - term investments, down from $ 69 million in September as the company spent heavily on clinical trials for the drugs it is developing and absorbed higher licensing fees at its specialty drug business, which has added 12 new drugs to its stable of products.

Preveceutical said in a release that Australia's specialized hospitals with strong clinical trial capabilities as well as the country's diverse...

The clinical trial, referred to as Capita, showed that Prevenar 13 prevented community - acquired pneumonia in the elderly subjects.

A single clinical trial could cost as much as $ 100 million, and the FDA usually approves about one in 10 clinically tested drugs.

As an example, consider a hypothetical biotech company, Medico, that has a drug candidate in advanced clinical trials as a treatment for skin canceAs an example, consider a hypothetical biotech company, Medico, that has a drug candidate in advanced clinical trials as a treatment for skin canceas a treatment for skin cancer.

By Michael First and Jerome C. Wakefield, Special to CNN Editor's Note: Michael First, M.D., a professor of clinical psychiatry at Columbia University, has worked as a forensic psychiatric expert in capital cases such as the trial of Zacarias Moussaoui, the convicted co-conspirator in the 9/11 attacks, and is the editor of the current edition of the psychiatric diagnostic manual, DSM - IV - TR.

In late clinical - trial findings published Wednesday in the New England Journal of Medicine, the monoclonal antibodies known as solanezumab and bapineuzumab were shown ineffective at changing the downward cognitive trajectory of Alzheimer's patientIn late clinical - trial findings published Wednesday in the New England Journal of Medicine, the monoclonal antibodies known as solanezumab and bapineuzumab were shown ineffective at changing the downward cognitive trajectory of Alzheimer's patientin the New England Journal of Medicine, the monoclonal antibodies known as solanezumab and bapineuzumab were shown ineffective at changing the downward cognitive trajectory of Alzheimer's patients.

With China expected to experience rapid growth in clinical trials over the short term, the Australian industry needs to remain competitive by focusing on quality factors as a differentiator.

As a board - certified internist at Cedars - Sinai Medical Center in Beverly Hills, Dr. Udani was among the first physicians in America to become a certified physician investigator for clinical trials.

(Culver City, CA August 27, 2013)-- After Oryzatein ® was recognized as the first plant - based rice protein to equal animal - based whey protein for muscle building and repair in a clinical trial published last month, an «Oryzatein ® Inside» endicia is being provided to manufacturers who use the ingredient in their food products.

But clinical trials that compared exercise to antidepressants found that exercise was as effective in treating major depression as medications.

Many experts throughout history, including Hippocrates, considered and prescribed phytochemicals as medications and clinical trials have proven the effectiveness of many in enhancing health states.

In a clinical trial led by the University of California, Davis Medical Center, babies that were given Evivo showed an 80 % reduction in potentially harmful bacteria such as E.coli, Clostridia, Staph, and Strep and a 79 % increase in good gut bacteriIn a clinical trial led by the University of California, Davis Medical Center, babies that were given Evivo showed an 80 % reduction in potentially harmful bacteria such as E.coli, Clostridia, Staph, and Strep and a 79 % increase in good gut bacteriin potentially harmful bacteria such as E.coli, Clostridia, Staph, and Strep and a 79 % increase in good gut bacteriin good gut bacteria.

Our Cord Blood Education workshop here in Halifax with Insception Lifebank has shared a wealth of knowledge with expectant parents regarding clinical trials and treatments as well as emerging research.

Throughout 2017, ongoing clinical trials in regenerative medicine using cord blood have offered hope to families facing life - changing medical conditions, such as cerebral palsy and autism.1 For some of these families, banking their baby's cord blood with ViaCord gave them the opportunity to participate in this groundbreaking research.

As part of a major medical center, we can offer our young patients evaluation and treatment that includes access to state - of - the - art equipment, advanced therapies, clinical trials and a team of specialists in pulmonology and from other clinical disciplines.

Her experience in college health, at the AIDS clinical trials UNC - Chapel Hill, and as a sexual health and family planning counselor with Planned Parenthood solidified her belief in providing direct care coupled with evidence - based information, and community resources that offer realistic options and reinforcement of individual needs.

In addition to clinicians focusing on patient care, we have clinicians who also are educators and scholars as well as translational or clinical trial scientists.

The PhD course focuses on various aspects of human (donor) milk, with as main study a randomized clinical trial towards the effects of human donor milk in very low birth weight infants (the Early Nutrition Study).

Our Cord Blood Education workshop here in Halifax with Insception Lifebank has shared a wealth of knowledge with expectant parents regarding clinical trials and treatments as well -LSB-...]