«For many years, the rheumatology and dermatology communities have been trying to understand which patients with psoriasis go on to develop psoriatic arthritis and how we might detect it earlier
in the disease course,» explained senior investigator Cheryl Barnabe, MD, MSc, of the McCaig Institute for Bone and Joint Health and the O'Brien Institute for Public Health, Cumming School of Medicine, at the University of Calgary, Alberta, Canada.
The authors suggest that while it is not certain that this particular strategy or drug could be effective, it is possible that either not enough drug was administered or that the drug needs to be administered earlier
in the disease course.
Our results demonstrating Gleevec's high efficacy in CML tell us that in applying the drug to other cancers, we need to diagnose and treat patients earlier
in the disease course.
Finally, we know that treatment early
in the disease course is associated with improved efficacy of drugs and better outcomes, such as reduced risk for surgery.
While of obvious importance to patients, these findings are also tremendously important to hospitals and policymakers who are concerned with initiating palliative care earlier
in the disease course.
«The more robust response rates of first - line therapy, compared with second or later lines, suggest that immunotherapy administered earlier
in the disease course is more beneficial,» says Dr. Adams.
The really important questions are whether this therapy can be given safely; early
in the disease course; and as second - line treatment, replacing an autologous stem cell transplant.
Additionally, our wellness examinations serve to detect potential problems early
in their disease course.
Not exact matches
But they've been hampered by somewhat skeptical physicians who still aren't sure that the drugs are worth their price (their topline costs are around $ 14,000 per treatment
course); part of the problem is that it's unclear whether or not those dramatic cholesterol reductions actually translate into broader health outcomes like a reduced risk of stroke or heart attack
in heart
disease patients.
Now comes word of another moonshot project from the company's Google X division: an ingestible
disease - detecting pill containing thousands of microscopic magnetic particles that
course through a person's bloodstream
in search of malignant cells, according to the Associated Press.
When Jedd Wolchok, a cancer doctor and immunologist leading a Yervoy trial at Memorial Sloan Kettering, examined a melanoma patient's scan 12 weeks after he'd received his
course of treatment, the results were utterly disappointing — just like those of any other metastatic patient
in the final throes of the
disease: The tumors had gotten bigger, and there were more of them.
Whilst we can't know the future of
course, for financial planning purposes the probability is that life expectancy on average will increase
in the future as medicine advances to cure or limit the big killers (cancer, cardiovascular
disease etc).
Alabama and Mississippi: the most unhealthy region (e.g., the most obese, the most with cardiovascular
diseases and etc.), the highest illiteracy rate, the highest teenage pregnancy rates, the most cities ranking
in the top 25 most crimes, the most likely to regect scientific facts, the least taxed, the least to be unionized thus the highest proportion of the population
in poverty... and of
course, the most religious....
Of
course, after years of sex education
in schools we have not managed to stem the high rates of teenage pregnancy or been able to prevent ever increasing rates of sexually transmitted
disease.
Of
course, to put the human race down
in its beginning — like a
diseased dog — would have been far from glorious.
Instructions or presentations of the family, clan, or city are explained and justified by tales — «charter myths»
in Malinowski's term — or knowledge about religious ritual, authoritative and absolutely serious ritual, and about the gods involved, is expressed and passed on
in the form of such tales; then there are the hopes and fears connected with the
course of nature, the seasons, and the activities of food supply; there is the desperate experience of
disease.
Of
course, unchecked free radicals and a lack of antioxidants
in your diet leads to sickness and
disease.
And of
course, OSTEOPOROSIS IS A MAJOR
DISEASE IN THE U.S. — COULD IT BE ANY MORE CLEAR THAT WE ARE DOING SOMETHING WRONG... THAT MAYBE MILK DOES NOT PREVENT OSTEOPOROSIS?
When I was doing research for my new
course (The Endo Toolkit), I found some research that revealed that cortisol levels are significantly higher
in women with advanced endometriosis as compared to women without the
disease.
Of
course, as someone with heart
disease I can't eat the kind of brownies I used to — the kind with a stick of butter
in every batch.
The main task of the ECS is to improve the quality of life of coeliac patients with following activities: protecting the interests of coeliac patients, informing the public about coeliac
disease and glutenfree food and it's regulations, cooperation with medical staff, cooperation with food manufacturers and HoReCa, Crossed - Grain Symbol trademark licensing
in Estonia, finding new opportunities for glutenfree products, dissemination of coeliac information, organising training
courses, cooperation with other social organisations.
Of
course, whether I am having monogamous sex or casual encounters, I always protect myself from
diseases as well as unwanted pregnancies and I never put my son or my own well - being
in jeopardy.
I've read (
in Scientific American I believe) recent research suggesting that H Pylori helps regulate the human immune system (for its own gain, of
course, but ours too by suppressing auto - immune
diseases).
The question that is raised
in the documentary (and of
course in the actual literature) is whether or not a general disregard for the impact of modern medical practices on the microbiome is responsible to some degree for the increase
in noncommunicable
disease.
Rehberg says all Concussion Wise ™
courses are based on the latest recommendations and guidelines, including those developed by the Centers for
Disease Control and Prevention, American Medical Society for Sports Medicine, National Athletic Trainers» Association, American Academy of Neurology, and the recommendations from the 4th International Conference on Concussion
in Sport (Zurich 2012).
In addition, studies are needed on the effects of lactation on the
disease course of women who develop each of the conditions we considered.
We compared outcomes after medical versus surgical management of biliary tract
disease in pregnant patients.We reviewed the clinical
course of patients with symptomatic cholelithiasis during pregnancy from 1992 to 2002 at two university hospitals.Seventy - six women with 78 pregnancies were admitted with biliary tract
disease.
Many things can change
in the
course of 24 hours: a person can go from single to married, discover the cure to a
disease, or travel from one continent to another.
Bipolar Disorder is one of the biggest mental health concerns
in the United States, but instead of addressing the true, spiritual nature of the
disease, the normal
course of treatment involves harmful pharmaceuticals.
«Nigerians must appreciate the need to urgently tackle poverty, educational backwardness, outbreak of
diseases, infant and maternal mortality, infrastructural deficit, and of
course the psychological impact of the loss of several loved ones due to the insurgency
in the region.»
Speaking on the 31st Convocation lecture of the institution titled» Stepping Out Into The World; Potential Well - Being, Change
in Lifestyle And Cancer Education», the don lamented the drain the
disease cost on the nation's resources through just about five per cent of the cancer patients (10,000) that had resources to go abroad where they pay between $ 10,000 - $ 15,000 per patient for a three to five weeks
course of Radiotherapy.
Early detection of breast cancer with screening mammography means that treatment can be started earlier
in the
course of the
disease, possibly before it has spread.
But physicians
in the empirical tradition, to which Aristotle was exposed by his physician father, learned how to predict the
course of
disease from observation.
This is the measure of how infective a
disease is, or how many people one infected person will pass it on to
in the
course of their illness.
Data presented by Doctors Without Borders also suggests that when it comes to surviving Ebola it does not seem to matter what day
in the
course of the
disease an Ebola patient shows up at the clinic
in west Africa.
Alzheimer's is a
disease for which there are still no treatments that fundamentally alter the
course of the
disease, as trial after trial of drug candidates have ended
in failure.
The new findings suggest a simple blood test can accurately predict levels of a protein called amyloid beta
in the brain that begins appearing early
in the
course of the
disease before symptoms appear.
What little encouraging Alzheimer's treatment data does exist — including that around a promising drug called aducanumab — suggests medications that have gone through clinical trials seem to work better earlier
in the dementia
disease course, before patients develop full - blown Alzheimer's.
The finding could change the
course of research into the role of oxidation
in age - related
diseases.
Once the most feared
disease on the planet, smallpox killed countless people
in the
course of human history.
The authors — Martin Llewelyn, a professor of infectious
diseases at Brighton and Sussex Medical School, and nine British colleagues — point to recent studies that have shown shorter
courses of certain drug classes such as quinolones are as effective as the longer
courses that have been recommended
in the past.
People who ate a diet high
in nuts and legumes, low - fat dairy, whole grains, fruits, and vegetables and low
in red and processed meat, sugar - sweetened beverages and sodium were at a significantly lower risk of developing chronic kidney
disease over the
course of more than two decades, new Johns Hopkins Bloomberg School of Public Health research suggests.
The answer, of
course, has a lot to do with changing perceptions of anxiety, and
in particular our tendency to treat as a
disease what used to be viewed as an innate tendency — or even a moral failing.
«The pause is welcome
in the sense that hopefully it will relieve some of the immediate urgency
in terms of trying to chart a
course forward,» agrees Michael Osterholm, who heads the University of Minnesota's Center for Infectious
Disease Research and Policy
in Minneapolis, and is a member of the NSABB.
Beyond this frontier, algorithms can provide a more precise prognosis for the
course of a
disease — potentially reshaping treatment of progressive ailments or addressing the uncertainties
in end - of - life care.
According to Dr. Dotson, the increased usage of corticosteroids and biologic medications among black children
in the study could suggest a more severe
disease course that may be attributable to worse intrinsic
disease in black children.
In the future, doctors could thus use Gab2 as a biomarker and infer the
course of the
disease by measuring Gab2 levels.
And of
course, for many, many years there was a period — many listeners may remember — there was a, now it seems an sort of an astonishingly naïve period, I believe
in the 1970 for a while, when antibiotics were so effective and the level of this sort of transmissible
disease was falling down so low that some people were really thinking that we had, kind of, beaten these kinds of infectious
diseases.
Over the
course of the year - long trial, the patch appeared to stabilise the
disease in all four treated eyes, while the untreated eyes continued to deteriorate.
This pattern of cross-infection from animals to humans is par for the
course in emerging infectious
disease.