Sentences with phrase «in the gene expressions between»

The authors are now working to understand how selection acts differently on males and females, and how this leads to differences in gene expression between the sexes.

«We observed small but significant changes in the gene expressions between normal and diabetic corneas,» said Mehrnoosh Saghizadeh Ghiam, PhD, assistant professor of biomedical sciences and neurosurgery, a researcher in the Regenerative Medicine Institute Eye Program and the lead author of the study published in the journal PLOS ONE.

Relative differences in gene expression between treatment with L - arginine (groups 3 and 4) were represented as fold change.

Significant changes in gene expression between anoikis - resistant and total population cells are shown in Table 1.

Not exact matches

Between 10 days and three months, the cells exposed to smoke had a two - to four-fold increase in the amount of an enzyme called EZH2, which works to dampen the expression of genes.

In addition, the researchers have quantified the preservation level of this gene expression between humans and mice.

«It is exciting to find a correlation between brain circuitry and gene expression by combining high quality data from these two large - scale projects,» says David Van Essen, Ph.D., professor at Washington University in St. Louis and a leader of the Human Connectome Project.

The researchers also looked at the expression of a gene involved in the control of wing development, and found similarity between the lab - induced supersoldiers and the natural ones.

The second duplication appears in supplemental figure S6, where a scatterplot purporting to show gene expression similarities between the cell lines was used twice.

In contrast, when the OncoFinder algorithm is applied to the data, a clear correlation between next generation sequencing and microarray gene expression datasets was seen.

The gene expression similarities between this common condition and the current findings in late - stage RP suggest that the canine RP models could serve as stand - ins to evaluate the effectiveness of pharmaceutical interventions that target innate immunity pathways in AMD

When the team measured gene expression first in the stem cells, and then re-evaluated the cells once they had become neurons, very specific differences emerged between the cells derived from bipolar disorder patients and those without the condition.

Despite differences in brain size, the researchers found striking similarities between primate species of gene expression in 16 regions of the brain — even in the prefrontal cortex, the seat of higher order learning that most distinguishes humans from other apes.

Differences between populations in gene expression have not been well characterized before.

The researchers developed algorithms to use in a «systems biology modeling cycle,» in which they repeatedly fit a model to gene expression data obtained from laboratory experiments until a good fit was obtained between the predicted and the measured outcomes.

In addition, the team examined the relationship between sleep and the expression of a gene in the feather follicles involved in producing dark, melanic feather spotIn addition, the team examined the relationship between sleep and the expression of a gene in the feather follicles involved in producing dark, melanic feather spotin the feather follicles involved in producing dark, melanic feather spotin producing dark, melanic feather spots.

The team also recently obtained a grant from the National Medical Research Council in Singapore to pursue a study using the probe to examine the relationship between key Parkinson's disease - linked genes and MAO - B expression and activity to further understand the causes of the disease and illuminate the role of MAO - B in this.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

They built a new software tool called MIxT (Matched Interactions across Tissues) that uses computational and statistical methods to find and investigate links between gene expression in different body tissues.

In the new study, a team led by Vanessa Dumeaux during her time at McGill University examined links between gene expression in breast cancer tumors and in the bloodstreaIn the new study, a team led by Vanessa Dumeaux during her time at McGill University examined links between gene expression in breast cancer tumors and in the bloodstreain breast cancer tumors and in the bloodstreain the bloodstream.

Basically, the gene makes a molecule involved in preparing other genes for expression, helping to distinguish between regions of genes that should be manufactured and those that are silent genetic filler.

Rather than listing specific genes that manifest themselves differently, or are differentially expressed, between queens and workers, the team looked for genes with similar expression patterns across samples that may be involved in maintaining the structural, behavioural and functional differences observed between queens and workers.

This information is not only important because it can now help scientists try to understand how the differences between queen and worker may arise through interactions among genes, but also for the evolution of ants, and in the evolution of gene expression more generally.

The researchers» results suggest that structural and functional differences between queens and workers result from the differential expression of evolutionary conserved sets of genes, or genes that are basically expressed in the same manner throughout evolution among all ant species.

«This technique will be useful for other studies interested in characterising the link between gene expression and physical, external traits.»

The new study, published this month by Molecular Autism in a special issue on sex differences in autism, further shows a stronger correlation between the expression level of RORA and that of genes regulated by RORA in males.

In fact, the researchers found gene expression differences between ASD and non-ASD in genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cyclIn fact, the researchers found gene expression differences between ASD and non-ASD in genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cyclin genes related to translation and immune / inflammation functions, as well as cell adhesion and cell cycle.

Moreover, the gene expression responses in CD4 + T cells stimulated with WNV differed between individuals with previous asymptomatic infection and those who had neuro - invasive WNV disease.

Another provocative observation from the new study was that transient gene expression events during brain development set up broad distinctions in neural fate between cells in different areas in the cerebral cortex.

Moreover, the correlation between RORA and target gene expression in the cortex is much higher in male mice.

For example, the researchers were able to identify previously unknown gene expression differences between the neural stem cells that give rise to the brain's deep structures versus its neocortical surface, and to show that molecular signatures of different neural cell types arise much earlier in brain development than previously realized.

«We didn't set out to study the relationship between the epigenetic chromatin marks and gene expression during development, but rather to analyze the function of these marks in DNA processing.

Recent studies have found elevated levels of this protein in post-mortem brain samples of patients with MS.. In this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of the galanin gene between healthy controls and MS patientin post-mortem brain samples of patients with MS.. In this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of the galanin gene between healthy controls and MS patientIn this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of the galanin gene between healthy controls and MS patients.

We predicted a link between gene expression evolution across species and the degree of sexual selection, but this is the first statistical evidence for it and shows how powerful sexual selection can be in leading to major changes in how a gene is expressed.»

The team found deep conservation of certain processes that likely reflects similar underlying regulatory processes between mouse and man, but there were also significant differences in gene expression during kidney development, as well as in the timing, scale, organization, and molecular profile of key cell types and cell structures.

These gene expression variances could explain the differences in disease risks, or disease symptoms, between males and females, Clark says.

The researchers showed these relationships between ecRNA production and gene activity in neurons included genes whose expression is altered by neuronal activity and genes implicated in developmental and neurodegenerative disorders.

But 19 genes showed significant shifts in expression between humans and apes.

A baseline study shows major differences in gene expression in the hypothalamus and pituitary between male and female pigeons.

The case for direct interaction was bolstered by similarities between gene expression profiles of plants with various deficiencies in photoreceptors and COP1.

Pääbo has also found that differences in gene expression (how active a gene is) may have played a role in creating the gap between chimp and human brains.

We know that all differences between these appendages are specified by the expression of the Hox gene Ultrabithoax (Ubx) in the haltere and its absence from the wing (1).

The researchers discovered that DNA methylation — a fundamental, life - long process in which a methyl group is added or removed from the cytosine molecule in DNA to promote or suppress gene activity and expression — does in fact vary between FLS from the knees and hips of RA patients.

Using quantitative RT - PCR we confirmed the expression profile of five genes (colony - stimulating factor 1 receptor [Csf1r], Cd68, Pex11a, Emr1, and Mcp1) in each of the 24 samples and found excellent agreement between the microarray and RT - PCR expression data (mean Pearson correlation coefficient = 0.91, microarray versus RT - PCR expression; Supplemental Table 3, http://www.jci.org/cgi/content/full/112/12/1796/DC1).

The results showed a correlation between changes in his brain and alterations in the expression of many families of genes in his blood.

Gene expression divergence levels were obtained from [71] and were measured in terms of the number of commonly co-expressed genes between human and mouse one to one orthologs.

Differences in gene expression are likely to specify much of the phenotypic differences between and within species.

Dluzen et al. demonstrate that differential expression of a set of miRNAs correlate with expression of a larger set of target genes in pathways which are relevant to disease pathogenesis and are differentially expressed between patients of different genetic background.

If, for instance, a researcher finds that dozens of genes in a microarray are differentially expressed on a high - fat purified ingredient diet compared to a low - fat GB diet, it is tempting to conclude that gene expression was altered due to the differences in fat levels between the diets.

Part of the normal variation, which is equally present between blastocysts of both groups, can be observed in the gene expression of levels mtDNA encoded OXPHOS proteins.