Sentences with phrase «in the human genome called»

Efforts include the National Institutes of Health Diabetes Genome Anatomy Project and another NIH - sponsored venture, the International HapMap Project, which is creating a map of regions in the human genome called haplotypes, where the underlying DNA influences common diseases like diabetes.

Not exact matches

His premise was that music could be broken down in an objective way by trained musicians; he called his effort the Music Genome Project, a riff on the drive to map human DNA.

Around 75 per cent of the supposed functionless DNA in the human genome is transcribed into so - called non-coding RNAs (ribonucleic acid).

Francis Collins, director of the National Human Genome Research Institute in Bethesda, Maryland, and a key participant, calls the map «a dream come true.»

Since the publication of the human genome sequence in 2001, scientists have found that the so - called junk DNA that lies between genes actually carries out many important functions.

In the past few years, it has become clear that a phenomenon called alternative splicing is one reason human genomes can produce such complexity with so few genes.

«This study gives deep new insights into the life of a parasitic fluke in the human bile duct, and was enabled by the development of an exciting new genome assembly tool called OPERA - LG in our lab.

Francis Collins, who heads the National Center for Human Genome Research in Bethesda, Maryland, called the find the «most exciting news of this year in genetic medicine».

Hidden in the tangled, repetitious folds of DNA structures called centromeres, researchers from Harvard Medical School and the Broad Institute have discovered the hiding place of 20 million base pairs of genetic sequence, finding a home for 10 percent of the DNA that is thought to be missing from the standard reference map of the human genome.

Once the vector is ready, the Baylor team wanted to be able to guide it to a certain part of the genome every time, so they turned to a technique called ΦC31, which was known to work in human and mouse cells.

«Having the genome sequence is like having part of the instruction manual,» says study author Richard Wilson of Washington University in Saint Louis (W.U.), echoing the famous 2000 comment of then Human Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&genome sequence is like having part of the instruction manual,» says study author Richard Wilson of Washington University in Saint Louis (W.U.), echoing the famous 2000 comment of then Human Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&genome a «glimpse of our instruction book.»

«These non-coding RNAs have been called the «dark matter» of the genome because, just like the dark matter of the universe, they are massive in terms of coverage — making up over 95 percent of the human genome.

PARIS — As scientists race to finish a rough draft of the human genome, a European consortium is about to launch an effort to pinpoint every key spot in our genetic code where cells turn genes on and off by adding a molecule called a methyl group.

Using a recently developed genome - editing technique called CRISPR, a Chinese team has successfully altered two target genes in cynomolgus monkeys, paving the way for the development of monkey models that mimic human diseases.

I moved to the NIH in 1993 to take on this role of directing what was then called the Center (and is now called the Institute) of Human Genome Research, stepping into the shoes of Jim Watson.

Fragments of genetic material called transposons, or «jumping genes,» inserted themselves long ago in the human genome and have been a powerful force in our evolution, Tina Hesman Saey reported in «The difference makers» (SN: 5/27/17, p. 22).

COVER Cheap, widely available, and easy to use, the genome editing system called CRISPR earned Science's 2015 Breakthrough of the Year laurels for many great feats and some controversial ones — including the alteration of DNA in human embryos.

The hostilities involve institutions (M.I.T. and Harvard versus University of California), gender (Doudna, Charpentier, Zhang), geography (east versus west coast) and what you might call über - institutions (the Broad Institute, which has become an empire of genomic research under Lander's direction, especially after his leading role in the Human Genome Project, versus the Howard Hughes Medical Institute, whose president, Robert Tjian, is based at Berkeley and has co-authored at least one CRISPR paper with Doudna, also an HHMI investigator).

And Celera said in a statement that the company «welcomes» the Clinton - Blair policy, calling it «completely consistent» with Celera's plan to publish the human genome in a peer - reviewed journal and make the information «available to researchers for free.»

The so - called Human Genome Project — Write aims to synthesize entire genomes from their chemical components and get them to function in living cells.

A week later, a network of stem - cell researchers, bioethicists and policy experts called the Hinxton Group, said that after meetings in Manchester, UK, they had concluded that research involving genome editing in human embryos has «tremendous value to basic research».

That money, most of it from federal grants through the Human Genome Project, has paid for the first rough guides to the 3 billion nucleotides in human DNA: maps studded with thousands of landmarks called «sequence tagged sites» (Science, 25 October 1996, p. Human Genome Project, has paid for the first rough guides to the 3 billion nucleotides in human DNA: maps studded with thousands of landmarks called «sequence tagged sites» (Science, 25 October 1996, p. human DNA: maps studded with thousands of landmarks called «sequence tagged sites» (Science, 25 October 1996, p. 540).

Specifically, Dudley and his colleagues were curious about segments of our genome called human accelerated regions, or HARs, first identified in 2006.

But now, scientists at the Gladstone Institutes have found a way to efficiently edit the human genome one letter at a time — not only boosting researchers» ability to model human disease, but also paving the way for therapies that cure disease — by fixing these so - called «bugs» in a patient's genetic code.

The team used genome editing techniques to stop a key gene from producing a protein called OCT4, which normally becomes active in the first few days of human embryo development.

His work is part of a boom in human genetics research in Saudi Arabia over the past decade, which has culminated in a Saudi version of a human genome project, called the Saudi Human Genome Program (Shuman genetics research in Saudi Arabia over the past decade, which has culminated in a Saudi version of a human genome project, called the Saudi Human Genome Program (Shuman genome project, called the Saudi Human Genome Program (genome project, called the Saudi Human Genome Program (SHuman Genome Program (Genome Program (SHGP).

Ethicists have renewed the call for caution in handling gene - editing CRISPR, which has the potential not only to cure congenital and other serious illnesses but also can make permanent changes in human genome that can be heritable by a person's offspring.

A second, perhaps less - hyped initiative (called the Encyclopedia of DNA Elements, or ENCODE) set out to delineate all functional elements in the human genome.

While these variants are all determined in comparison to the human genome reference, genomes submitted for the Cancer Sequencing Service are additionally analyzed for somatic variants called in comparison to the baseline genome within the submitted pair or trio.

Recent studies of Salmonella Typhimurium (called ST313), which is responsible for a large part of this invasive disease, have shown that there are signs in its genome that it has adapted to a new human niche.

The Ion Proton ™ System is the first benchtop non-imaging semiconductor sequencing system capable of human - targeted genome, exome, or transcriptome sequencing in a few hours — with DNA - to - variants called in a single day.

Earlier this year (May 29), Nature published a thematic issue called «The Human Proteome» with three articles announcing various international efforts to describe the protein complements of the genome, including an article describing the Swedish - based Protein Atlas effort and its plan to release a first draft based on transcriptomics and protein profiling (www.nature.com/nature/journal/v509/n7502/full/509645a.html) later in the year.

The organizers of the project, called GP - write (for work in model organisms and plants) or sometimes HGP - write (for work in human cell lines), envision it as a successor to the Human Genome Project (retroactively termed HGP - read), which 25 years ago promoted rapid advances in DNA sequencing technohuman cell lines), envision it as a successor to the Human Genome Project (retroactively termed HGP - read), which 25 years ago promoted rapid advances in DNA sequencing technoHuman Genome Project (retroactively termed HGP - read), which 25 years ago promoted rapid advances in DNA sequencing technology.

A new technology for engineering genomes called CRISPR has implications for human aging as well as the resurrection of certain extinct species, according to Harvard Medical School scientist and engineer George M. Church, who briefed science writers Oct. 19 during CASW's New Horizons in Science, part of the ScienceWriters2014 conference in Columbus, Ohio.