The central question is how,
in the human organism for example, 100 000 genes have been orchestrated to yield about 250 different cell types, which then become assembled as the human body.
Not exact matches
Each —
in addition to happening right now (or very recently)-- is a reminder of how frail the
human organism can be compared with the microorganisms that compete with us
for earthly dominance.
These
organisms are vital food sources
for fish and walruses, which
in turn are vital to
humans.
In a special way, so Christian faith holds, the divine Spirit came to concrete human expression in Jesus, but God needs for his existence no psychophysical organis
In a special way, so Christian faith holds, the divine Spirit came to concrete
human expression
in Jesus, but God needs for his existence no psychophysical organis
in Jesus, but God needs
for his existence no psychophysical
organism.
The same is true
for the fetus,
for the living
organism in relation to its environment,
for the
human «I»
in relation to the «Thou.»
A medical school,
for instance, is a research and often also a healing center, directly concerned with the increase of knowledge about the
human organism and with its health; but it is also a training center where men are prepared to work
in many other institutions of the society, from private practice to public health offices.
Whitehead's well - known notion of the Stage of Romance
in education gets its power from the fundamental aesthetic need of the
human organism for novelty and zest
in experience.
Which amounts to saying that the complexification of Matter, at the point it has now reached
in the
human social
organism, is physically incapable of advancing further if the Mind does not play a part, not only with its capacity
for technical organization, but with its purposive and affective powers of arrangement and inner tension.
If God possesses even emotional attributes that
humans possess, it all of a sudden would mean that God had biological needs, since emotions are important
for the performance and life of the
organism they exist
in.
While it is evident to science that there is a functional «teleonomy» or machine - like purposiveness
in individual
organisms (
for example, the fish's eye is constructed so as to enable it to see under water, the heart toward pumping blood, the
human brain toward problem - solving, etc.), still there is no hard evidence that life itself, terrestrial evolution or the universe as a whole has any overarching meaning.
Theologians like James Packer and Clark Pinnock are correct
in arguing that the Bible must be read as a whole, coherent
organism,
for it is not only
human words but also God's Word.
He emphasized the active, integrating self (rather than the frail, victimized ego); held to a «soft» (rather than a «hard») determinism; had a strong interest
in future, goal - directed strivings (rather than origins); emphasized the
organism as a whole centered
in the self (rather than a conflict view of personality); regarded the striving
for worth and power (rather than sexual striving) as the central dynamic
in mental health and illness; emphasized the possibilities
for continuing change
in the later years (rather than regarding the early years as utterly decisive)(2) It is clear from these motifs
in Adler's thought that his vision of
human beings was positive and growth - centered.
The reaction of any person who begins to leaf through this illustrated chronicle of
human gestation will surely be extraordinary as well, and the book should be helpful
in promoting «bonding» of all readers with all unborn babies, as it graphically documents the contention (made,
for example,
in this issue by William Saunders) that from zygote to embryo to fetus to birth, each
human organism is nothing but
human.
Studies comparing
human milk from preterm mothers with that from term mothers suggest that these immunologic benefits may be even greater
for preterm infants because secretory immunoglobulin A (IgA), lysozyme, lactoferrin, and interferon are found
in greater concentrations
in preterm
human milk compared with term milk.2 — 4 Very low birth weight (VLBW) infants do not benefit from the transplacental transfer of maternal immunoglobulins that occurs primarily after 34 weeks of gestation.5 These infants are exposed to abundant pathogenic
organisms during neonatal intensive care unit (NICU) hospitalization and may benefit from the host defense factors present
in preterm
human milk.6 — 9
Traditional genetic approaches together with the new wealth of genomic information
for both
human and model
organisms open up strategies by which drugs can be profiled
for their ability to selectively kill cells
in a molecular context that matches those found
in tumors.
Many events that
humans call disaster rarely are
for plants, animals and other
organisms, at least
in the long term.
Selfish elements live
in a wide variety of
organisms (including
humans), and have devised a variety of methods
for getting themselves passed on.
«Once we can build that sort of database
for the
human organism, it helps us much better understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the Genome Sequencing Center at Washington University
in St. Louis.
It's «entirely possible» that the new finding has implications
for female mate perception
in other
organisms, including
humans, says neurobiologist Harold Zakon of the University of Texas, Austin.
In the last decade, however, complete genome - sequence information and increasingly powerful bioinformatic tools have allowed us to generate and analyse draft interactome maps both
for humans and
for other model
organisms.
This new technology has major implications not just
for plant biology, but also
for cellular biology research
in every type of
organism, including
humans.
That's why researchers are engineering plants to produce key parts of viruses and bacteria,
in the hope that the
human body will take them
for invaders and start producing antibodies against the
organisms.
In humans, it holds the promise of curing genetic disease, while in other organisms it provides methods to reshape the biosphere for the benefit of the environment and human societie
In humans, it holds the promise of curing genetic disease, while
in other organisms it provides methods to reshape the biosphere for the benefit of the environment and human societie
in other
organisms it provides methods to reshape the biosphere
for the benefit of the environment and
human societies.
Their end goal is to identify specific populations of neurons
in the fruit fly brain that are necessary
for emotion primitives — and whether these functions are conserved
in higher
organisms, such as mice or even
humans.
For example, if you want to transpose the function of a protein
in a model
organism to the corresponding
human protein, you can make use of orthology to detect the right protein.
The budding yeast, Saccharomyces cerevisiae, is a prime
organism for studying fundamental cellular processes, with the functions of many proteins important
in the cell cycle and signaling networks found
in human biology having first been discovered
in yeast.
Given the obvious concerns
for human ecological health —
in terms of climate change, heavy metal toxification, indoor air quality, air pollution, plastics
in the oceans, and things like that — there will be a large - scale trend to buildings that start to act like
organisms.
Indy codes
for a protein that resembles a membrane protein found
in many
organisms, from bacteria to mammals, including
humans.
This finding represents one of the first examples of a genome - wide significant genetic factor to be identified
for binge eating
in model
organisms or
humans.
For more than a decade, the husband - and - wife team has been investigating how a large protein complex called SAGA, which helps control gene activity
in organisms from yeast to
humans, influences developmental processes.
Now we have to see whether what we observed
in these two
organisms also holds true
for humans.
«By means of basic research on model
organisms, we are trying to understand
human genome instability to identify elements, which,
in the future, might be able to be explored as targets of new anti-tumour medicines,» explains the researcher responsible
for the project and director of Cabimer, Andrés Aguilera.
Many of the
organisms that wound up living on the panels are known as fouling species — microorganisms, algae, and invertebrates that anchor to boat hulls, jetties, and aquaculture facilities and wreak havoc
for both
humans and local marine communities — so lighting up marinas and harbors may not be
in our best interest.
Given the rapid succession of generations
in yeast, we can use it as a model
organism — and study the mechanisms of aneuploidy
in much greater detail to find out whether we can derive from it new approaches
for diagnosing and treating
human diseases.»
«A protein that first made sex possible — and is still used
for sexual reproduction
in many of Earth's
organisms — is identical to the protein used by dengue and Zika viruses to enter
human cells,» Snell said.
In Britain, the regulations governing genetically modified organisms came into force in 1992, before the implications for gene therapy were appreciated, and in practice the law has not been applied strictly to human
In Britain, the regulations governing genetically modified
organisms came into force
in 1992, before the implications for gene therapy were appreciated, and in practice the law has not been applied strictly to human
in 1992, before the implications
for gene therapy were appreciated, and
in practice the law has not been applied strictly to human
in practice the law has not been applied strictly to
humans.
The reason
for the disparity may be that the standard computer annotation method was largely developed
for the genomes of simple (prokaryotic)
organisms, not
for the more complex sequences found
in the genomes of
humans and other eukaryotes.
He says HGS was getting «diminishing returns» from its investment
in TIGR since Venter had steered his outfit into sequencing
organisms of little medical importance, and into
human genome sequencing, also of limited value
for a company like HGS that is interested
in genes as drug targets (not untranslated DNA that makes up most of the genome).
«This is how genetics has been understood
for over a century
in diverse
organisms including
humans, most animals we are familiar with, and many plants.»
Fruit flies are small insects that are often used
for genetic research as they reproduce quickly, are easy to breed
in laboratory conditions and share many of the same fundamental mechanisms and pathways found
in more complex
organisms such as
humans.
«The key breakthrough came from using a fruit fly model of
human ALS and FTD that allowed us to screen these 400 candidates
for ones that block brain cell death
in a living
organism,» says Lloyd.
«Our study reveals a spectrum of methods that nature uses to allow
organisms to adapt to different environments,» said senior author Kerstin Lindblad - Toh, Scientific Director of Vertebrate Genome Biology at the Broad Institute: «These mechanisms are likely to be also at work
in humans and other vertebrates, and by focusing on the remarkably diverse cichlid fishes, we were able to study this process on a broad scale
for the first time.»
A full realisation of the medical potential of stem cells
for human health will likely depend on a reinforcement of, and development of a whole continuum of studies ranging from those
in vivo using model
organisms, to cell - based therapies
in the clinic.
Studies
in organisms such as mice, meanwhile, can be used to examine more complex functions or perfect novel approaches
for use
in humans.
Still, he said, the new data, «has important implications
for understanding the genesis of cancer and the interaction between
human cells and other microbial or viral
organisms in or around us.»
Identifying a full list of imprinted genes
for humans and model
organisms will give scientists a springboard to characterize the mechanisms and functions of imprinting, says Ian Morison of the University of Otago
in Dunedin, New Zealand.
If the model
organism genome projects are to be maximally useful
in assigning functions to
human DNA sequences, they will need to utilize the powerful tools
for determining gene function that are available to them so that not only the sequences of the genes, but also their biological functions, are determined.
Graber will work
in the institution's Kathryn W. Davis Center
for Regenerative Biology and Medicine, where scientists are working to identify the molecular pathways responsible
for regeneration
in organisms that have retained the ability to regenerate lost and damaged tissues and organs, then screening
for drugs with the potential to reawaken these dormant regeneration pathways
in humans.
ONE - PARENT SAMPLE SET PARENTAL GUIDANCE RULES: Maternally methylated (red dots) and paternally methylated (blue dots) regions across the
human autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute for Biomedical Research ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expre
human autosomal chromosomes, based on studies of uniparental disomy samplesGENOME RES, 24:554 - 69, 2014 RESEARCHERS Kazuhiko Nakabayashi, Division Chief, Department of Maternal - Fetal Biology, National Research Institute
for Child Health and Development, Tokyo, Japan; David Monk, Principal Investigator, Epigenetics and Cancer Biology Program, Bellvitge Institute
for Biomedical Research
ORGANISM Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker for imprinted genes, though it's possible for patterns of differential methylation to exist in tissues where both alleles are expre
Human METHODS Bisulfite - seq; bisulfite - chip Methylation is typically associated with the silencing of the nonexpressed allele, making it a convenient marker
for imprinted genes, though it's possible
for patterns of differential methylation to exist
in tissues where both alleles are expressed.
D melanogaster represents a useful experimental system
for analyzing the functions of neuronal circuits the results from which can translate to neuronal function
in other
organisms, perhaps even including
humans.