Significantly, disabling both anti-apoptotic proteins, Bcl - 2 and Bcl - xL, in conjunction with Mcl - 1, caused profound cell death of leukemia cells
in the test tube as well as in animal models of AML.
The hnRNPA2 protein forms liquid droplets
in a test tube as seen by light microscopy.
It starts with an intriguing premise: Anna Fitzgerald (Abigail Breslin) was created
in a test tube as «spare parts» for her older sister, Kate (Sofia Vassilieva), who has leukemia.
(And of course in this instance there is that uncomfortable reality that we all happen to be
in the test tube as we're running the experiment, as scientists have noted with concern for 50 years.)
Not exact matches
While
testing a new vacuum
tube that drives a radar set known
as a magnetron, he discovered that a chocolate bar he had
in his pocket melted.
Falk wrote that the book contains many incorrect claims such
as «Meyer correctly concluded that no RNA molecule had ever been evolved
in a
test tube which could do more than join two building blocks together.
It is an amazing process of refinement by which the exceedingly human activity that goes on
in the laboratory — broken
test tubes, bright ideas, discussions with colleagues — ends up
as a single sentence
in a journal: «The reaction was found to be aided by the addition of 3 % NaOH.»
DR. WALTER ZIMDAHL, SYRACUSE «They called me «the opportunist,»» recalls Walter Zimdahl, who made his way through medical school, after three seasons
as a Syracuse fullback, by washing dishes, sweeping out the gym, helping
in the county morgue and scouring
test tubes.
Discover 11 mind - blowing experiments such
as creating a sunset
in a
test tube and many more.
The audience roars with laughter
as Polish tells how he initiated select new members into the cell biology lab he worked
in after college with strategically placed miniature dry - ice bombs fabricated from plastic Eppendorf
test tubes.
Hughes ran into conflict with the university and his former sponsor, the National Institutes of Health (NIH), over his efforts to diagnose genetic diseases — such
as Tay - Sachs disease and cystic fibrosis —
in test -
tube embryos scheduled for implantation (Science, 24 January, p. 472).
In 2012, she and postdoctoral fellow Prashant Mali teamed up on CRISPR - Cas9, a molecular complex that bacteria use as a primitive immune system; other scientists had recently gotten it to cut specific locations on DNA floating in test tube
In 2012, she and postdoctoral fellow Prashant Mali teamed up on CRISPR - Cas9, a molecular complex that bacteria use
as a primitive immune system; other scientists had recently gotten it to cut specific locations on DNA floating
in test tube
in test tubes.
But the
test tube burger, rolled out to the press
in 2013, has helped put a spotlight on the question of how the U.S. government will regulate the emerging field of cellular agriculture, which uses biotechnology instead of animals to make products such
as meat, milk, and egg whites.
If these
test -
tube results are confirmed
in infected animals and people, the viral proteins could be targets for anti-Ebola vaccines
as well
as for drugs that treat Ebola infections.
The recent birth of two
test tube foals
in the UK,
as part of a collaborative project conducted by leading fertility experts, could help benefit rare breed conservation and horses with fertility problems.
One is being
tested here
as the midwife uses a finger stick to collect 300 microliters of blood, just five or six drops,
in a small
tube, then she treats the samples with a DNA / RNA shield, essentially detergent to prevent degradation.
Shea notes that although he and his colleagues have yet to finalize their measurements on how well their nanoparticles bind to various PLA2 molecules, their
test -
tube results suggest that they could have a similar high affinity for PLA2s
as their previous nanoparticles had for melittin, the bee venom protein that stopped the toxin
in animal studies.
The catalyst is initially dissolved
in the ingredients (left) but begins to form oily clumps
as the reaction progresses (middle), ending up
as a solid
in the bottom of the
test tube (right) after all the ingredients are used u
It's not
as though someone has created a Frankenstein's monster
in a
test tube — they have given the best gift there is.»
But the Doudna / Charpentier team,
as they reported
in a landmark paper published online by Science on 28 June 2012, at that point had only used CRISPR to cut DNA
in test tube studies.
The molecular biology wars may also be ending
in a rapprochement, he says,
as the «
test tube jockeys» belatedly recognize that they need the «stamp collector» systematists after all.
Their
test tube experiments suggest that the resulting molecule behaves
in almost exactly the same way
as natural carbonic anhydrase.
Never had a
test tube looked
as colourful and appetising
as the one Catarina Prista, Joana Moura, and their team presented at the 2007 Rencontres Sciences, Art & Cuisine
in Paris, an international molecular gastronomy contest promoted by Hervé This, one of the pioneers of molecular gastronomy.
To solve such a complex puzzle, Jasmine McCammon, a postdoctoral researcher
in Sive's lab, enlisted the zebrafish
as a «living
test tube.»
Now the whole world is a
test tube into which antibiotics and antivirals are being dumped, and we simply may not have them on demand
in the future
as these microbes become increasingly resistant.»
The researchers note that this study of digestion
in the
test tube is limited by not including the roles of gut cells, which absorb and secrete metabolites
as well.
The term
in vitro, from the Latin meaning
in glass, is used, because early biological experiments involving cultivation of tissues outside the living organism from which they came, were carried out
in glass containers such
as beakers,
test tubes, or petri dishes.
For this particular research problem they developed a so - called y - maze experiment, a proboscis choice
test in which a y - shaped
tube system is used
as an extension of the flower's corolla.
Practically speaking, Zhang's saCas9 — with an adeno - associated virus serving
as a vector — allows CRISPR to work
in vivo,
as opposed to simply
in test tubes.
In tests at SLAC's Facility for Advanced Accelerator Experimental Tests (FACET), a DOE Office of Science User Facility, beams of positrons stayed tightly bundled as they traveled through the plasma
tests at SLAC's Facility for Advanced Accelerator Experimental
Tests (FACET), a DOE Office of Science User Facility, beams of positrons stayed tightly bundled as they traveled through the plasma
Tests (FACET), a DOE Office of Science User Facility, beams of positrons stayed tightly bundled
as they traveled through the plasma
tube.
The research was carried out by experts
in synthetic and theoretical chemistry, materials and electron microscopy and builds on Professor Khlobystov's concept of carbon nano
test tubes (World's tiniest
test tubes, Guinness Book of World Records 2005), where the nanotube acts
as a container for molecules.
As a result, it strongly bound elastase
in the
test tube, preventing the enzyme from degrading connective tissue.
Study after study has found that while these substances do work
as antioxidants
in the
test tube, popping the pills does not provide any benefit.
Saccharin was listed
as an «anticipated human carcinogen»
in 1981, sucralose has been shown to weakly mutate genes
in test tubes, and aspartame has triggered fears about everything from autism to multiple sclerosis.
«Vaccines, antibiotics, organ transplants, and
test -
tube [
in vitro] babies were each initially viewed
as unnatural,» Stock says.
Using genetic techniques, the Imperial team knocked out the Hhat function
in pancreatic cancer cells and,
as they hoped, the cancer cells showed substantially reduced growth and ability to spread
in a
test -
tube assay.
Currently, lung function is measured using a
test known
as spirometry,
in which patients blow through a
tube; their progress is tracked over time.
Just
as silicon - based components use electric current to represent 1's and 0's, bio-based circuits use concentrations of DNA molecules
in a
test tube.
Furor about
in vitro fertilization after Louise Brown, the first «
test tube baby,» was born
in 1978 gave way to acceptance
as grateful parents gave birth to more and more healthy babies and welcomed them into their families.
Hartl and Horwich challenged the widely held notion put forth by Nobel Prize winner Christian Anfinsen that proteins fold spontaneously
in cells, just
as they do
in test tubes.
In research published in this week's issue of the journal Science, a team from Whitehead Institute for Biomedical Research used common baker's yeast as a living test tube to show how just a small amount of a Parkinson's - related neuronal protein called alpha - synuclein (aSyn) can convince neighboring proteins to abandon their normal shape and form these deadly cluster
In research published
in this week's issue of the journal Science, a team from Whitehead Institute for Biomedical Research used common baker's yeast as a living test tube to show how just a small amount of a Parkinson's - related neuronal protein called alpha - synuclein (aSyn) can convince neighboring proteins to abandon their normal shape and form these deadly cluster
in this week's issue of the journal Science, a team from Whitehead Institute for Biomedical Research used common baker's yeast
as a living
test tube to show how just a small amount of a Parkinson's - related neuronal protein called alpha - synuclein (aSyn) can convince neighboring proteins to abandon their normal shape and form these deadly clusters.
In Lindquist's lab, yeast cells — which share the core cell biology of human cells — serve as living test tubes in which to study the problem of protein misfolding and to identify possible solution
In Lindquist's lab, yeast cells — which share the core cell biology of human cells — serve
as living
test tubes in which to study the problem of protein misfolding and to identify possible solution
in which to study the problem of protein misfolding and to identify possible solutions.
In previous experiments, Rust has demonstrated that Kai proteins isolated in test tubes are able to maintain their ability to function as a biological clock and respond to metabolic signal
In previous experiments, Rust has demonstrated that Kai proteins isolated
in test tubes are able to maintain their ability to function as a biological clock and respond to metabolic signal
in test tubes are able to maintain their ability to function
as a biological clock and respond to metabolic signals.
Therefore, iPS cells displayed properties of ES cells
in animals
as well
as in test tubes.
My go - to herbalist, author and American Herbalist Guild member David Winston of Broadway, New Jersey, says
in his book, Herbal Therapy and Supplements: A Scientific and Traditional Approach, that animal and
test -
tube studies are convincing enough to recommend eating maitake regularly
as part of a treatment plan for high cholesterol, high blood pressure, insulin resistance, and even hepatitis B. (Placebo - controlled studies
in people have yet to be conducted.)
As with other suspicious substances
in our food, most research on BHT and BHA has been confined to animals and
test tubes, and not directly studied
in people, making it hard to say conclusively that this is dangerous.
«Looking at a biopsy and deciding if its cancer and what kind is not
as precise
as measuring glucose
in a
test tube.
In test tubes, peppermint has been discovered to have substantial antiviral and antimicrobial activities, strong antitumor and antioxidant actions,
as well
as some antiallergenic potential.
However, while these studies may show that limonoids
in foods such
as grapefruit may offer some protection from cancer, these were
test tube studies and clinical studies need to be conducted before claims can be made.
However, adding ascorbic acid (vitamin C) will not increase the number of lactobacilli
in test tube experiments, possibly because ascorbic acid isn't
as strong of an acid
as citric acid: http://www.ncbi.nlm.nih.gov/pubmed/21411170