Scientists now plan to examine how differences
in timing impact on parasites and the biological mechanisms controlling their rhythms, to better understand how to tackle infection.
Not exact matches
«We're a bit hesitant on the ability of [President - elect Donald] Trump to, one, get legislation passed
in the
time frame that the market is expecting and, two, the
impact of that legislation if and when it is passed,» says the global macro strategist for Pavilion Global Markets
in Montreal.
Important factors that could cause actual results to differ materially from those reflected
in such forward - looking statements and that should be considered
in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the
timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases
in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest
in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions
in the industries and markets
in which we operate
in the U.S. and globally and any changes therein, including fluctuations
in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain
in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse
impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse
impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the
impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both
in the U.S. and abroad; 20) the effect of changes
in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction
in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or
impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco
in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations
in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
By creating a well - written and
impacting press release, it is possible to go from unheard of to popular
in no
time, especially if your press release is picked up by a big news company.
«The President multiple
times reaffirmed
in general to all of us, and looked at Larry Kudlow, and said Larry go get it done,» Sasse said after exiting a White House meeting with the President about trade and agriculture that he attended with several governors and congressional leaders who represent states that they say will be adversely
impacted by the President's recently announced tariffs.
At a
time when debate about a potential outer harbour project south of Perth is building momentum, a look at the history of development
in Kwinana's industrial zone provides an illustration of the
impact of government intervention
in the state's economy, for better or worse.
The first
time this Internet thing got built up, I was just a kid
in my parents» house building websites, but I couldn't have a big
impact.
...
in 2015, University of Toronto sociologist Melissa Milkie published a study showing that the amount of
time children aged 3 to 11 spent with parents had no measurable
impact on their emotional well - being, behavior, or academic success.
According to the statement, Viacom (VIAB) had previously expected to complete what it called a «significant» agreement with an SVOD (subscription video on - demand) provider
in the most recent quarter, but said that the «recent and highly public governance controversy negatively
impacted the
timing and its ability to achieve an optimal outcome with partners.»
«When raising a first -
time fund
in an»em erging geography», it's important to be sensitive and respectful to the other entities
in the local community that may be
impacted,» said Lewis and Clark Principal Scott Bernstein.
Finally, despite our incredible growth over a short period of
time, Transportation
Impact is a family, working together to be the best
in the industry.
In a statement about the ad, Williams said she hadn't started playing tennis with the explicit intention of breaking down barriers, but that, «Over
time, I became much more conscious of the
impact I had, and I became more conscious of what I had to do to make a difference.»
In Same Side Selling, my co-author Jack Quarles, a long -
time procurement expert, and I noted how decisions are often
impacted by unconscious actions.
«We all prepare ahead of
time for what we know is coming up,» Amy Florian, chief executive of Corgenius, told advisors Wednesday at Schwab
IMPACT 2017
in Chicago.
While the International Mobility Program will certainly help a few American companies to «park» their foreign employees
in Canada during this tumultuous
time, it's the broader policy changes that will tangibly
impact the tech community at home, as well as foreigners seeking a safe and stimulating place to innovate.
If a client comes to your office for the first
time, they walk
in to a bog standard room with 4 plain walls, a couple of desks and a chair; they won't feel an
impact from your business, even if you are the best
in your industry.
«God not only uses our trails to better equip us to help others, he also brings us the right people at the right
time with the right resources so that our
impact in the world will be greater.»
, fitness breaks legitimized
in the work schedule, requiring all employees to take a substantial part of their vacation
time off, turning off email while on vacation, providing paid parental leave for new parents and encouraging both mothers and fathers to take advantage with no adverse career
impact, paid
time off for volunteer activities, and more.
The surplus was still down 47 percent from a year earlier, with the trade balance remained
in deficit as the yen's decline has pushed up costs of imported fuels immediately while its
impact on exports will take some
time to be fully seen.
This includes the
impact of chance opportunities, lucky breaks, and being
in the right place at the right
time.
Russ Corsi, who worked nearly 32 years for Pittsburgh - based PPG, a global supplier of auto glass, says larger sunroofs are also more prone to weakening over
time as the pane absorbs
impacts from bumps
in the road, twists and turns of the car's frame, and «thermal shock» — the expanding and contracting from sudden temperature changes.
While there is a «magic factor» to getting a cover story
in the New York
Times or Forbes — which can change the trajectory of a business and is hard to quantify
in terms of exact
impact — PR professionals can and must think of creative ways to measure outcomes
in a more quantitative way.
A global economic slowdown hasn't had much
impact on this resilient market as people continue to turn to alcohol
in good
times and bad.
For most of us, our suppliers really have a huge
impact on our business and
in tough
times, they can help us to survive.
The financial
impact didn't come through
in Box's second - quarter earnings, so investors will be looking carefully for any effect this
time around.
Maybe it's a sign of the
times that we feel compelled to equate structural interdependencies and cascading
impacts in the business world to biological systems and their fragility.
Schulz opposes becoming the junior coalition partner because this has previously
impacted the party
in a negative way, every
time it joined forces with Merkel.
«The government shutdown will have an
impact on real estate transactions should it continue for an extended period of
time,» said Elizabeth Mendenhall, president of the National Association of Realtors,
in a statement to CNBC.
Despite the pressure of the «mandatory to - do list» and deadline - sensitive items, I believe it's critically important to find
time for daily activities that are not necessarily as obvious
in impact to the business.
For many women, even spending that precious, limited free
time in a dressing room to find enough different combinations to wear to work is both exhausting and unappealing — a thought that hasn't made a large enough
impact on retail, yet.
My evidence of that is if you ask Chris Nassetta, CEO of Hilton, which until the merger of Marriott and Starwood was the largest hotel company
in the world, he actually went on record numerous
times saying they haven't seen a material
impact.
He is also planning to remain the voice of Starbucks» social
impact efforts, like when he asked his employees to write «Come Together» on cups during the government shutdown
in 2011 or his decision to offer full - and part -
time employees tuition for a college education.
«It was awesome, a high -
impact, high - energy, hackathon kind of environment,» says working group participant Mike Green, director of the ScaleUp Campaign, a nonprofit partnership to encourage local innovation based
in Portland, Ore. «Since you were pitching multiple
times, you had to have your game on.»
They are cross-departmental and given the resources to make a huge
impact in a short amount of
time.
The «return on
time» doesn't spend on that task is infinite,
in addition to gaining that same
time to invest
in a higher
impact project.
It
impacts the most important metric to measure: quality of hire, which typically factors
in performance, ramp - up
time, cultural fit and tenure.
Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions
in the industries and markets
in which United Technologies and Rockwell Collins operate
in the U.S. and globally and any changes therein, including financial market conditions, fluctuations
in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand
in construction and
in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the
impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges
in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature,
impact or
timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future
timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies
in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including
in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the
timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any
time due to various factors, including market conditions and the level of other investing activities and uses of cash, including
in connection with the proposed acquisition of Rockwell; (7) delays and disruption
in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the
impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes
in political conditions
in the U.S. and other countries
in which United Technologies and Rockwell Collins operate, including the effect of changes
in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates
in the near term and beyond; (16) the effect of changes
in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations
in the U.S. and other countries
in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result
in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including
in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted
in their operation of their businesses while the merger agreement is
in effect; (21) risks relating to the value of the United Technologies» shares to be issued
in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.
Elon Musk is only second to Steve Jobs
in modern
times, who has that vast
impact in different industries and sectors.
Over and over again, they not only stand the test of
time, they result
in true
impact.
The ratio increased from 3.27
times at Q4 2017 due to the decrease
in twelve - month rolling EBITDA caused by the lower revenue (mainly FX
impact, periodic and Other revenue), the IFRS 15 accounting change and the restructuring provision.
I've observed for some
time how CEOs and other executives can't keep their cybersecurity programs
in a silo where only a certain number of people fully understand and appreciate their
impact.
Jonathan Chaplin, New Street Research, and Tom Eagan, Telsey Advisory Group, discusses the Department of Justice's lawsuit to stop the AT&T -
Time Warner merger and how it could
impact other mergers
in the media space.
Your goals should be quantifiable
in order to set up
time lines, directed so they relate to the success of the business, consequential so they have
impact upon the company, and feasible so that they aren't beyond the bounds of actual completion.
We instructed our employees to plan ahead for projects or goals that may be
impacted by taking
time off: keep your coworkers and managers informed, let your colleagues know at least two weeks ahead of
time when you'll be on vacation, and report
in on days you need to be out unexpectedly.
But one significant
impact, which can cost a company considerable
time and money to repair, is
in the area of public relations.
The Organization of the Petroleum Exporting Countries also said oil inventories across the most industrialized countries rose
in January for the first
time in eight months, a sign the
impact of its output cuts may be waning.
This is an important
time in the development of our global community, and it's a
time when many of us around the world are reflecting on how we can have the most positive
impact.
If your ideas can help reduce
time - to - collection periods, and if those ideas can be sustained over a long period of
time, you'll have a positive
impact on NWC, and that,
in turn, will enhance the company's value.
«When you have thousands of people coming to your site every day, if making one little change like putting a security logo on your checkout page makes a 1 percent difference
in conversion rate a day that can make a huge
impact on your bottom line over
time.»
Make your elevator speech ride with the
times Claims of huge returns and outrageous market grabs aren't credible anymore, say Suzanne Muchin and Rachel Bellow at ROI Ventures, a social -
impact market strategy firm based
in Chicago.