Sentences with phrase «in trabecular meshwork»

Dr. Vranka's project studied Versican, a large proteoglycan that is known to interact with many other proteins also present in the trabecular meshwork, which is thought to be the primary contributor to outflow resistance.

Dr. Keller was awarded the 2010 Shaffer Prize for Innovative Glaucoma Research for her research investigating the role of Glycosaminoglycans (GAGs) in fluid outflow resistance in the trabecular meshwork of the eye.

Project: Pathological Alterations in the Trabecular Meshwork Following Vitrectomy and Lens Extraction: A Model of Oxidative Stress

Carla J. Siegfried, MD Washington University School of Medicine, St. Louis, MO Funded by The Alcon Foundation Project: Pathological Alterations in the Trabecular Meshwork Following Vitrectomy and Lens Extraction: A Model of Oxidative Stress

Not exact matches

Its impact appears to reduce the ability of the cells in the eye's trabecular meshwork to continually move the clear aqueous humor out of the front of the eye and dump it into the body's general circulation, said Liu, corresponding author of the study in the journal Investigative Ophthalmology & Visual Science.

Other data obtained in this report (BrdU nitroblue tetrazolium staining by alkaline phosphatase and fluorescence due to fluorescein) would further suggest that putative stem cells are located in the posterior limbus between the peripheral endothelium and the trabecular meshwork.

The area of the trabecular meshwork and its surrounding posterior limbus in the human, however, showed considerable fluorescence indicative of cell division (Figure 6B).

Conclusions: It is suggested stem - like cells may be sequestered in a niche at the junctional region where the corneal endothelial cells and the trabecular meshwork come together.

No activity was observed in the central endothelial tissues or the limbus between the trabecular meshwork and Schwalbe's line.

In this report, no telomerase activity in the limbal region from Schwalbe's line to the trabecular meshwork was detecteIn this report, no telomerase activity in the limbal region from Schwalbe's line to the trabecular meshwork was detectein the limbal region from Schwalbe's line to the trabecular meshwork was detected.

There was also increased fluorescence in the area of the trabecular meshwork and posterior limbus of greater magnitude than in the unwounded condition (Figure 7B).

However, we have found a fluorescent marker for nestin, a neural crest stem cell marker, in the posterior limbal region of the human anterior segment in the vicinity of both the trabecular meshwork and Schwalbe's line (unpublished).

When BrdU fluorescence assays were made on corneal transverse sections with fluorescein, fluorescence occurred in an area just at and adjacent to the trabecular meshwork, but was not seen at the corneal endothelium.

By way of contrast, considerable fluorescence was observed in the area of the trabecular meshwork and the posterior limbus (Figure 6B).

The authors say that it's possible that the new trabecular meshwork cells generated from the stem cell treatment could eventually succumb to the same mechanisms that caused the fluid buildup in the first place, but further research is needed in that area.

Project: Nanoengineered In Vitro Trabecular Meshwork ™ Model for Systematic Investigation of Aqueous Humor Outflow Resistance

In most instances, OH results from impaired drainage of aqueous humor through the trabecular meshwork ™.

TGF - Î ² 2 is known to elevate IOP by promoting increases in aqueous humor outflow resistance through the trabecular meshwork.

In the lamina cribrosa, like the trabecular meshwork we hypothesize that exosomes participate in the turnover of extracellular matrix and homeostatic signaling with cell neighbors, particularly in response to elevations in intraocular pressure / pulsationIn the lamina cribrosa, like the trabecular meshwork we hypothesize that exosomes participate in the turnover of extracellular matrix and homeostatic signaling with cell neighbors, particularly in response to elevations in intraocular pressure / pulsationin the turnover of extracellular matrix and homeostatic signaling with cell neighbors, particularly in response to elevations in intraocular pressure / pulsationin response to elevations in intraocular pressure / pulsationin intraocular pressure / pulsations.

Our lab has recently shown that endogenous TGF - Î ² 2 expression can be markedly and significantly attenuated in human trabecular meshwork cells and porcine anterior segments using the compound XJB -5-131, a novel antioxidant that targets a cell's mitochondria.

RPB investigators have found that the normally spongy cells of the trabecular meshwork (TM) might be hardened by calcification in the eyes of people with glaucoma.