Sentences with phrase «in translational cancer research»

I remain committed to a career in translational cancer research and to alleviating the global cancer burden.

Not exact matches

A clinical trial conducted by researchers at the Virginia G. Piper Cancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic cCancer Center Clinical Trials, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen), showed that a new drug called MM - 398, given in combination with 5 - flourouracil (5FU) and leucovorin, produced a significant overall survival rate in patients with advanced, previously - treated pancreatic cancercancer.

Professor Paolo Boffetta (MD), the Annals of Oncology associate editor for epidemiology and Director of the Institute of Translational Epidemiology at the Icahn School of Medicine at Mount Sinai in New York (USA), commented: «These results are extremely important in showing that reducing cancer mortality can be achieved: priority should be given to research in cancers with unfavourable trends, such as pancreatic cancer, and in reducing cancer mortality disparities, both between countries (Central / Eastern versus Western Europe), and within countries, for example, between socioeconomic groups.

The research, which builds on previous work by Dr. Rassool and Dr. Baylin, was funded by a number of grants, including Stand Up To Cancer's inaugural Laura Ziskin Prize in Translational Research — a $ 250,000 grant awarded to the two researchers research, which builds on previous work by Dr. Rassool and Dr. Baylin, was funded by a number of grants, including Stand Up To Cancer's inaugural Laura Ziskin Prize in Translational Research — a $ 250,000 grant awarded to the two researchers Research — a $ 250,000 grant awarded to the two researchers in 2012.

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

My next career step was to accept a 6 - month position, which was then extended by an additional year, to establish a translational research laboratory for cancer immunotherapy at the Gustave Roussy Cancer Campus, a major nonprofit health care, research, and teaching institution in cancer immunotherapy at the Gustave Roussy Cancer Campus, a major nonprofit health care, research, and teaching institution in Cancer Campus, a major nonprofit health care, research, and teaching institution in Paris.

Focusing on basic research for the functional regulation of innate and adaptive immunity and on translational research for cancer immunotherapies, the National Key Laboratory of Medical Immunology has been conducting innovative research and exploration, and is becoming a rising star in the international immunology community.

So how are these huge shifts in the research firmament — multidisciplinarity, translational research, and commercialization — affecting one of the largest funders of basic biomedical science in the country, Cancer Reseresearch firmament — multidisciplinarity, translational research, and commercialization — affecting one of the largest funders of basic biomedical science in the country, Cancer Reseresearch, and commercialization — affecting one of the largest funders of basic biomedical science in the country, Cancer ResearchResearch UK?

A team under Professor Scheffler, consisting of researchers from the Bonn University Hospital, the Life & Brain Center, The German Consortium for Translational Cancer Research, Tufts University Boston / Massachusetts, and other institutes in the USA, has now developed a new method that is expected to combat such complex brain tumors better.

Looking ahead, cancer research looks set to thrive — particularly in the translational research arena and the development of new therapeutics.

Witt - Enderby is on the grant review panel for the Susan G. Komen Breast Cancer charity, which is placing greater emphasis on translational research, and a corresponding increase in suitable bids.

In a significant breakthrough, the Translational Genomics Research Institute (TGen) has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.

The lab of co-author Dr. Robert Bast Jr., an expert in ovarian cancer and vice president for translational research at MD Anderson, inserted gel - bound carbon nanotubes into the ovaries of rodents to mimic the accumulations that are expected for nanotubes linked to special antibodies that recognize tumor cells.

«The exciting research results being presented today underscore how transplants are becoming an increasingly successful treatment option for more patients with blood cancer than ever before,» said Jeffrey Miller, MD, moderator of the press conference and Deputy Director of the Masonic Cancer Center and the Clinical and Translational Sciences Institute at the University of Minnesota in Minneacancer than ever before,» said Jeffrey Miller, MD, moderator of the press conference and Deputy Director of the Masonic Cancer Center and the Clinical and Translational Sciences Institute at the University of Minnesota in MinneaCancer Center and the Clinical and Translational Sciences Institute at the University of Minnesota in Minneapolis.

The finding warrants research into adding drugs that could prevent the cancer from hijacking patients» repressive gene regulatory machinery, which might allow the original therapy to work long enough to eradicate the tumor, the researchers report in their National Institutes of Health - funded study, published in the current issue of Science Translational Medicine.

Dr. Kallioniemi's group is currently active in individualized systems medicine research on various cancers, with a special focus on rapid translational research to improve leukemia diagnostics and therapy.

Her research is both translational and clinical in nature and centers on the human genetics of healthy skin aging and diseases related to aging skin, including new treatments for advanced basal cell skin cancers.

«AML is a disease in which fewer than 30 percent of patients are cured,» said co-senior author Ulrich Steidl, M.D., Ph.D., associate professor of cell biology and of medicine and the Diane and Arthur B. Belfer Faculty Scholar in Cancer Research at Einstein and associate chair for translational research in oncology at MonResearch at Einstein and associate chair for translational research in oncology at Monresearch in oncology at Montefiore.

The results of the study were published this week in the journal Nature Medicine from researchers at Penn's Abramson Cancer Center, including senior author Carl H. June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the ACC, the University of Maryland School of Medicine, and Adaptimmune Therapeutics plc (Adaptimmune).

Joining forces with dermatologists and oncologists from the University Hospital in Zurich and backed by the University Research Priority Program «Translational Cancer Research,» Sommer's team was able to demonstrate that, in melanoma cells, the epigenetic factor EZH2 controls genes that govern tumor growth as well as genes that are important for the formation of metastases.

«High dose steroids is the only proven treatment for GVHD,» said James L. M. Ferrara, MD, DSc, Ward - Coleman Chair in Cancer Medicine Professor at the Icahn School of Medicine at Mount Sinai, Director of Hematologic Malignancies Translational Research Center at Tisch Cancer Institute at Mount Sinai.

«It's a dramatic increase in lifespan of animal models, as much as 25 percent,» said Leyuan Liu, PhD, assistant professor at the Texas A&M Institute of Biosciences and Technology's Center for Translational Cancer Research.

The Translational Genomics Research Institute (TGen) has uncovered possible genetic origins of breast cancer that spreads to the brain, according to a first - of - its - kind study published in the scientific journal PLOS ONE.

What we are changing is the amount of time that the formulation needs to be there, because we're accelerating how the drug enters the tissue,» says Giovanni Traverso, a research affiliate at MIT's Koch Institute for Integrative Cancer Research, a gastroenterologist at MGH, and one of the senior authors of a paper describing the technique in the Oct. 21 issue of Science Translational Mresearch affiliate at MIT's Koch Institute for Integrative Cancer Research, a gastroenterologist at MGH, and one of the senior authors of a paper describing the technique in the Oct. 21 issue of Science Translational MResearch, a gastroenterologist at MGH, and one of the senior authors of a paper describing the technique in the Oct. 21 issue of Science Translational Medicine.

The research team is led by Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the Abramson Cancer Center, along with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director of Blood and Marrow Transplantation in the Abramson Cancerresearch team is led by Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the Abramson Cancer Center, along with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director of Blood and Marrow Transplantation in the Abramson CancerResearch in the Abramson Cancer Center, along with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director of Blood and Marrow Transplantation in the Abramson Cancer Center.

This advance in breast cancer research reflects the mission of Stem Cell Reports to provide an open - access forum that communicates basic discoveries in stem cell research as well as translational and clinical studies.

The study is published in the October 2016 issue of Translational Cancer Research.

Following his postdoctoral training at the INSERM U. 311 in Strasbourg, France and the Cancer Genetics Branch at the National Human Genome Research Institute in Bethesda, Maryland, Dr. Azorsa joined the Translational Genomics Research Institute (TGen) based in Phoenix, Arizona.

Dr. Mardis received the Scripps Translational Research award for her work on cancer genomics in 2010, and was named a Distinguished Alumni of the University of Oklahoma College of Arts and Sciences for 2011.

In this webinar, a panel of experts will discuss their research and describe the use of real - time, label - free cell monitoring in their investigation of novel cancer targets and the impact of their work on translational research and drug developmenIn this webinar, a panel of experts will discuss their research and describe the use of real - time, label - free cell monitoring in their investigation of novel cancer targets and the impact of their work on translational research and drug developmenin their investigation of novel cancer targets and the impact of their work on translational research and drug development.

February 10, 2006 $ 25 million gift from Jules and Gwen Knapp will help build 10 - story medical research facility at the University of Chicago Jules and Gwen Knapp of Chicago have donated $ 25 million toward construction of a 330,760 - square - foot, 10 - story, state - of - the - art facility that will provide a new home for translational research programs in children's health, cancer, and other medical specialties at the University of Chicago.

«Pin1 changes protein shape through proline - directed phosphorylation, which is a major control mechanism for disease,» explains co-senior author Kun Ping Lu, MD, PhD, Director of Translational Therapeutics in the Cancer Research Institute at BIDMC and Professor of Medicine at Harvard Medical School who co-discovered the enzyme in 1996.

«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&cancer cell to block the expression of specific proteins involved in tumor growth.»

The designation recognizes the Center's collaborative environment and expertise in harnessing translational research to bridge scientific discovery to clinical delivery, with the ultimate goal of successfully introducing novel diagnostic, therapeutic and preventive approaches to cancer.

About the Anna - Maria Kellen Clinical Accelerator The Anna - Maria Kellen Clinical Accelerator, the clinical research program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innresearch program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innovCancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innResearch Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innresearch and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innovcancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innresearch ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innovation.

The Department of Translational Hematology and Oncology Research (THOR) conducts cancer research to develop and make available novel diagnostic tools, targeted therapies and clinical trials for direct use in patieResearch (THOR) conducts cancer research to develop and make available novel diagnostic tools, targeted therapies and clinical trials for direct use in patieresearch to develop and make available novel diagnostic tools, targeted therapies and clinical trials for direct use in patient care.

The Career Enhancement Program (CEP) is designed to identify, recruit and mentor both junior and established scientists, including underrepresented investigators (minorities and women), for performing translational research in endometrial cancer.

At the dinner, Parker also received the organization's highest honor for lay individuals, the Oliver R. Grace Award for Distinguished Service in Advancing Cancer Research, for his outspoken endorsement of cancer immunotherapy and substantial financial support of the Cancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strongCancer Research, for his outspoken endorsement of cancer immunotherapy and substantial financial support of the Cancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strongcancer immunotherapy and substantial financial support of the Cancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strongCancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strongCancer, an organization to which Parker has strong ties.

The Clinical Accelerator, building on 60 + years of CRI's dedication to funding the most innovative basic science in tumor immunology, enables experts to advance their most ambitious clinical and translational research ideas to cure cancer, and accelerates studies that one group or company could not do alone.

The program supports basic, pre-clinical, and translational research that can be directly applied to optimizing cancer immunotherapy in the clinic.

Wistar is expanding its research efforts on brain cancer, both in basic and translational research.

Winship Cancer Instituteâ $ ™ s Ned Waller and researchers from Childrenâ $ ™ s Healthcare of Atlanta and Yerkes National Primate Research Center were part of a recent Science Translational Medicine paper that draws a bright red circle around aurora kinase A as a likely drug target in graft - vs - host disease.

My translational research has focused on trying to find better ways to estimate recurrence risk in patients diagnosed with oestrogen - receptor positive early breast cancer, with the ultimate aim to better personalise our therapies for those patients who have the most to gain from them.

SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced the publication of a landmark study in which Danish researchers used the Prosigna ® Breast Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 andCancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 andcancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 andcancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.

The grant will support basic, pre-clinical, and translational research, which will provide information that can be directly applied to optimizing cancer immunotherapy in the clinic.

The system is available in the multi-mode FLEX configuration, which is designed to meet the needs of high - complexity clinical laboratories seeking a single platform with the flexibility to run the Prosigna Breast Cancer Assay and, when operated in the «Life Sciences» mode, process translational research experiments and multiplexed assays developed by the laboratory.

Our researchers in the Center for Childhood Cancer are conducting basic science, translational and clinical research geared toward finding a cure for childhood cancer and improving the toxicity of current treatCancer are conducting basic science, translational and clinical research geared toward finding a cure for childhood cancer and improving the toxicity of current treatcancer and improving the toxicity of current treatments.

LA JOLLA — The Salk Institute, which hosts a National Cancer Institute (NCI)-- designated cancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in cCancer Institute (NCI)-- designated cancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in ccancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in ccancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in ccancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting - edge basic and translational research in cancercancer.

The goal is to reward scientific excellence and to encourage innovative research in lung cancer prevention and translational medicine.

In 1999, Ashworth was appointed the first director of the ICR's Breakthrough Breast Cancer Research Centre, which is now internationally recognized, with more than 120 scientists and researchers working on aspects of the disease ranging from basic molecular and cellular biology through to translational research and clinicalResearch Centre, which is now internationally recognized, with more than 120 scientists and researchers working on aspects of the disease ranging from basic molecular and cellular biology through to translational research and clinicalresearch and clinical trials.