Sentences with phrase «in tumor development»

These signaling molecules may also play a role in tumor development in other organs, and are being evaluated in melanoma and other tumor types.

A recently recognized factor in tumor development is the role multiple vaccinations may play in cancer development in dogs and cats.

This lengthy period of time, compared to a mouse's lifetime, indicates that additional factors play a role in tumor development.

«There was this initial thought that [circulating tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that in the past year, several studies using more sensitive techniques have found such cells much earlier in tumor development, even before the tumor becomes visible by conventional imaging techniques.

Based on their results, Lu and her colleagues argue that the best strategy in such cases might be to use drug combinations that target multiple, parallel pathways involved in tumor development and maintenance.

Dr. Sergio Lira and his team at the Icahn School of Medicine at Mount Sinai, New York, asked if gut microbes have a hand in tumor development.

Our long - term goal is to translate this technology into clinical investigation of the pathological implication of exosomes in tumor development.

Dr. Yaffe's research focuses on the biology of the complex signaling pathways that cells use to respond to DNA damage and inflammation, particularly the role of protein kinases and modular binding domains in tumor development and anti-cancer therapeutics.

The effects of consuming emulsifiers were eliminated in mice devoid of microbiota (germ - free mice), and transplanting microbiota from emulsifier - treated mice to germ - free mice was sufficient to transfer alterations in intestinal epithelial cells» homeostasis, suggesting a central role played by the microbiota in tumor development.

A new study from the German Cancer Research Center has revealed that the entire species of Marmorkrebs originate from a single mother crayfish, in a clonal reproduction that may help shed new light on processes in tumor development.

For example, rodents consuming isoflavones have fewer tumors and / or a delay in tumor development in mammary, liver, colon, and prostate cancer (9, 10, 11, 12).

Investigators found that NPTX2 was expressed in all stages of kidney cancer, especially metastasis, which suggests it plays an important role in tumor development and progression.

The authors note that there are two different models of metastasis — one in which an advanced primary tumor disseminates metastatic cells late in its development, which would predict little genetic difference between primary and metastatic cells, and another in which metastasis occurs early in tumor development, which would predict significant genetic differences in metastatic cells that have evolved separately from those in the primary tumor.

The Cancer Center has a history of significant advances in cancer genetics, cancer biology, tumor immunology, and virology, including the identification of genes associated with different tumor types, the development of monoclonal antibodies used to study pathways and proteins involved in tumor development, and contributions to improved cancer treatments and diagnostic tests.

After identifying FAK's role in tumor development, François started looking for ways to get it in check.

The results obtained by the DKFZ researchers are the first to attribute an important role in tumor development to them.

Among the 108 genomes assessed, there were 23 genes harboring non-silent mutations in at least three independent tumors, suggesting an important role in tumor development or growth.

Cellular senescence is a major contributor to tissue aging and plays a context - dependent role in tumor development.

Because programmed cell death goes awry in leukemias and other cancers, Hu is currently examining lincRNA - EPS's function in normal and diseased human cells in an effort to determine whether it plays a role in tumor development and growth.

It is advised to monitor these pets closely throughout their lives for mammary (breast tissue) tumors as it is unknown what role the extra hormone exposure may have in tumor development.