I am a dedicated research scientist with a PhD in Biomedical Engineering and post-graduation experience in developing optical devices for application
in tumor imaging and point - of - care diagnosis.
Not exact matches
The first step
in the process is to surgically remove the patient's
tumor and ensure that the patient is cancer free by confirming that there is no sign of cancer on blood tests and
imaging studies.
«We're trying to build models that describe how
tumors grow and respond to therapy,» said Yankeelov, director of the Center for Computational Oncology at The University of Texas at Austin (UT Austin) and director of Cancer
Imaging Research
in the LIVESTRONG Cancer Institutes of the Dell Medical School.
«There was this initial thought that [circulating
tumor cells] are only present at late stage,» says Sollier - Christen, but she notes that
in the past year, several studies using more sensitive techniques have found such cells much earlier
in tumor development, even before the
tumor becomes visible by conventional
imaging techniques.
«Particularly
in such patients with underlying CKD, our modeling results support the integration of renal
tumor anatomic features at cross-sectional
imaging into decision making for treatment of small renal masses and may be used to provide a patient - centered framework for selection of optimal candidates for ablative therapy,» Kang said.
«We provide a framework for incorporating
tumor imaging features and renal function into treatment selection, which may help to inform physicians regarding the appropriateness of surgery
in patients with CKD,» Kang said.
In past
imaging studies, my colleagues and I noticed that cervical
tumors that took up a lot of glucose prior to radiation treatment tended to be more resistant to radiation therapy than other
tumors.
EM:
Imaging such as MRIs or CT scans, which reveal the mass and volume of the tumor, can fool you sometimes: The patient gets a scan, goes on a therapy, and when they return in a month for a second imaging, the structure and size of the tumor haven't c
Imaging such as MRIs or CT scans, which reveal the mass and volume of the
tumor, can fool you sometimes: The patient gets a scan, goes on a therapy, and when they return
in a month for a second
imaging, the structure and size of the tumor haven't c
imaging, the structure and size of the
tumor haven't changed.
«Clearer vision of what's inside a
tumor and what's going on
in there: Researchers combine powerful
imaging and metabolic analysis techniques to record disease events
in high resolution.»
These results demonstrate that noninvasive
imaging of EGFR activating mutation status
in primary and metastatic
tumors with 18F - MPG PET / CT is a valid strategy for stratifying NSCLC patients for EGFR - TKI treatment.
The first -
in - human PET / CT
imaging of 75 patients with 18F - MPG was performed to show that this tracer can be used as a companion diagnostic to identify NSCLC patients with EGFR activating mutant
tumors (primary
tumor or metastatic) with 84.3 % accuracy.
«With 18F - MPG PET / CT
imaging, we were able to quantitate EGFR - activating mutation status
in NSCLC patients (primary
tumor or metastatic) and directly determine / visualize the location (s) and morphology of the NSCLCs.»
Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for
imaging brain
tumors in the operating room — a finding that could have important implications for identifying and locating invading cells at the edge of a brain
tumor.
Magnetic resonance
imaging (MRI) has recently demonstrated glucose
imaging in mouse
tumors.
For example, just before von Eschenbach arrived, NCI had agreed to fund a now - $ 350 million screening trial to see if spiral computed tomography (CT) scans could detect lung
tumors missed by x-ray
imaging in former smokers.
To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS)
imaging, and demonstrated its use
in live cancer cells,
tumor xenograft tissues, primary neurons and mouse brain tissues.
In a study presented in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body
In a study presented
in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount of cell - free tumor DNA circulating in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body
in the featured clinical investigation article of the November issue of The Journal of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT
imaging to show that the amount of cell - free
tumor DNA circulating
in the bloodstream correlates with tumor metabolism (linked to cancer aggressiveness), not tumor burden (amount of cancer in the body
in the bloodstream correlates with
tumor metabolism (linked to cancer aggressiveness), not
tumor burden (amount of cancer
in the body
in the body).
«We synthesized an
imaging probe that stays dark
in normal tissues but switches on like a light bulb when it reaches solid
tumors.
The next step, he added, is to prove the applicability of photoacoustic
imaging in tumor models and ultimately
in patients.
The MRI
imaging detected metastatic
tumors, including micrometastases,
in lung, liver, lymph node, adrenal gland, bone, and brains of the mice.
Published
in Nature Photonics, this work might lay a foundation for
in vivo experiments that use light
in biomedical
imaging, optogenetics,
tumor treatment, and for recharging implanted medical devices.
In their current study, described online today in Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either imaging agents or anticancer compounds to tumor
In their current study, described online today
in Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either imaging agents or anticancer compounds to tumor
in Science, Discher and his colleagues copied short snippets of the CD47 protein, known as peptides, and attached them to nanoparticles designed to ferry either
imaging agents or anticancer compounds to
tumors.
A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance
imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (
imaging (MRI) agents that bind to the protein
in not only prostate cancer, but a range of
tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular
Imaging (
Imaging (SNMMI).
In the mice with cancer, the probes enabled detailed, 3 - D ultrasound
imaging of hypoxic
tumors.
While on one hand, there is significant potential
in the application of nanoparticles
in enhancing heat transfer for
tumor ablation and targeted drug delivery, there is also much promise
in improving
imaging and diagnostic protocols using them.
The technique is currently being tested
in a number of clinical applications, including
imaging breast
tumors, detecting skin cancer, and tracking blood oxygenation
in tissues.
They found that using the VASH collimator with an existing breast molecular
imaging system, they could get six times better contrast of
tumors in the breast, which could potentially reduce the radiation dose to the patient by half from the current levels, while maintaining the same or better image quality.
A newly devised
tumor - specific fluorescent agent and
imaging system guided surgeons
in real time to remove additional
tumors in ovarian cancer patients that were not visible without fluorescence or could not be felt during surgery, reports Alexander L. Vahrmeijer MD, PhD, head of the Image - guided Surgery group
in the Department of Surgery at Leiden University Medical Center
in the Netherlands.
«Novel
imaging model helps reveal new therapeutic target for pancreatic cancer: Antisense treatment
in preclinical models shows effectiveness against deadly
tumors.»
Frangioni is also CEO of Curadel, a company he started
in 2014 with the purpose of developing NIR contrast agents and
imaging systems to help surgeons identify glands, blood vessels, nerves, lymph nodes, and
tumors during operations.
• MRI
imaging technology is to be used
in specific situations, including for patients who have metastatic
tumors, for detecting head and neck paragangliomas and for patients
in whom radiation exposure should be limited; and
«This is really a big step forward
in imaging brain tumors and other issues in young patients,» said Journal of Medical Imaging associate editor Christoph Hoeschen of Otto - von - Guericke Unive
imaging brain
tumors and other issues
in young patients,» said Journal of Medical
Imaging associate editor Christoph Hoeschen of Otto - von - Guericke Unive
Imaging associate editor Christoph Hoeschen of Otto - von - Guericke Universität.
The new method, described
in a scientific paper that will be published Feb. 18
in The Lancet Oncology, is a modification of magnetic resonance
imaging that employs a novel contrast agent to find
tumors.
Researchers are rooting out these primary
tumors, many of them found
in the gastrointestinal tract or the lungs, with combined positron emission tomography and computed tomography (PET / CT), which provides both functional and structural
imaging of the body.
• Another
imaging technology, 18F - fluorodeoxyglucose - positron emission tomography / computed tomography, can be used
in patients with metastatic
tumors.
«If we can confirm that substantial signal levels originate from glucose
in the cell interior, this would be important additional information for
tumor imaging and functional MRI.
A further chemical modification
in the ProCA32 MRI contrast agent improves the ability for the compound to be retained
in blood for a longer period of time, permitting a longer window for
imaging and
tumor detection.
That would be a huge boon for therapy by allowing doctors to combine visual
imaging, such as MRI scans, of
tumors with knowledge of their genetic make - up, says experimental oncologist Janusz Rak of McGill University Health Centre
in Montreal, Canada.
The increase
in medical radiation exposure (from 0.53 mSv to 3.0 mSv) stemmed primarily from a rise
in the use of computer tomography (CT) scans (which use x-rays to create cross sectional images of inside the body to spot
tumors, clogged arteries, among other things), and nuclear
imaging tests, which involve injecting radioactive chemicals into the bloodstream that can be picked up by special instruments and used to create images of the body's inner structures.
Scientists at Georgia State University (GSU) with funding from the National Institute of Biomedical
Imaging and Bioengineering (NIBIB) have designed an imaging technique to detect early - stage liver tumors, and have proven it successful i
Imaging and Bioengineering (NIBIB) have designed an
imaging technique to detect early - stage liver tumors, and have proven it successful i
imaging technique to detect early - stage liver
tumors, and have proven it successful
in mice.
Regrowth or progression of
tumor was defined as any increase
in size of known residual
tumor on follow - up radiographic
imaging.
Baltimore, Md. (Embargoed until 12:30 pm EDT on Monday, June 8)-- A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance
imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (
imaging (MRI) agents that bind to the protein
in not only prostate cancer, but a range of
tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular
Imaging (
Imaging (SNMMI).
Can
tumors be detected when they are two to three orders of magnitude smaller than those currently detected with
in vivo
imaging modalities?
«An appropriate pH
imaging method would make it possible to visualize abnormal changes
in tissue and specifically metabolic processes of
tumors,» explains Franz Schilling.
They found that injecting into the carotid artery breast cancer cells that express markers allowing them to enter the brain — cells labelled with bioluminescent and fluorescent markers to enable tracking by
imaging technologies — resulted
in the formation of many metastatic
tumors throughout the brain, mimicking what is seen
in advanced breast cancer patients.
Emerging molecular
imaging agents join
tumor - seeking antibodies and signaling radioisotopes
in one radiopharmaceutical that is injected at the time of
imaging in order to track and report active receptors.
In an interview, Sharp said that to build new understanding of
tumors or ecosystems, scientists must be able to analyze oceans of new data generated by genomic sequencing,
imaging, and other advanced technology.
«Metastatic brain
tumors — often from lung, breast or skin cancers — are the most commonly observed
tumors within the brain and account for about 30 percent of advanced breast cancer metastases,» says Khalid Shah, MS, PhD, director of the Molecular Neurotherapy and
Imaging Laboratory
in the MGH Departments of Radiology and Neurology, who led the study.
In Vivo Imaging of siRNA Delivery and Silencing in Tumor
In Vivo
Imaging of siRNA Delivery and Silencing
in Tumor
in Tumors.
SNMMI NET Roadshow Advances
in Nuclear
Imaging and Therapy for Neuroendocrine
Tumors August 24, 2017 Grand America Hotel Seattle, WA