Sentences with phrase «in tumour formation»

MYC's role in tumour formation has stretched to include hiding cancers from the immune system.

This suggests that molecular mechanisms that have evolved to promote tissue repair are closely related to those involved in tumour formation, which could help us understand cancers.»

Not exact matches

But the chemical has since 1995 been ruled as unsafe in food for human consumption because it is capable of causing damage to one's DNA which can potentially lead to the formation of malignant tumours.

So reducing the risk of tumour formation or discovering a way to produce mature sperm in a test tube will have to be developed before we can even consider this in humans.»

«It was really surprizing to realize that oncogenic Pik3ca in basal cells induced the formation of luminal tumours, while its expression in luminal cells gave rise to heterogeneous and more aggressive tumors including basal - like tumors,» comments Alexandra Van Keymeulen, the first author of the paper.

It is essential, however, that these processes are carefully controlled in order to prevent unrestrained proliferation that can lead to the formation of tumours.

Our results suggest that frequent overexpression of Aurora Kinase in cancer may reduce RUNX3 transcription activity, leading to cell division and formation of tumours.

Blood vessel formation is also a critical step in the growth and spreading of cancerous tumours, as tumours require a dedicated blood supply to provide the nutrients for growth.

The adhesive properties of cancer cells play a key role in the formation and development of a tumour.

Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasion.

The findings suggest that defects in the epidermal barrier protected the genetically engineered mice against benign tumour formation.

The researchers studied ferric citrate and ferric EDTA, which have both previously been shown to worsen tumour formation in mice with colon cancer.

Adenoma (benign tumour) formation - driven by mutational activation of the Wnt signalling pathway in intestinal stem cells

The commentary highlights the possible fundamentally different and even opposing functions of intestinal fibroblast subpopulations in regulating inflammation and tumour formation and underscores the need to further characterize these cells to reveal new mechanisms underlying pathogenesis of chronic inflammation and cancer.

In the mouse experiments no tumour formation was found (within 100 days).

They also form a platform for discovering fibroblast lineages in other tissues and for examining fibroblast changes in ageing and disease (i.e, tumour formation).

Therefore, in some cases the process of inserting the healthy gene can increase the activity of cancer - linked genes, leading to tumour formation.

However, when these mice were tested for the ability to form tumours after activation of an oncogenic signal that causes colorectal cancer in humans, they showed dramatic resistance to tumor formation.

Expression of oncogenic β - catenin in Sox2 + young adult pituitary stem cells leads to formation of clusters of stem cells and induction of tumours resembling human adamantinomatous craniopharyngioma (ACP), derived from Sox2 - cells in a paracrine manner.

Professor Murray's research has been in a wide spectrum of areas, just a few of which are animal coat pattern formation, the spread and control of rabies, the mechanical theory of morphogenesis, brain tumour growth and control, marital interaction and divorce prediction, the benefits of cannibalism, bovine tuberculosis, wound healing and justifying tribal warfare.

The rats which were exposed to apigenin developed fewer tumours and also had significant delays in the formation of tumours in comparison to those rats which weren't exposed to apigenin.

Preliminary studies have shown that glycine may have a role to play in the treatment of certain cancers, including the prevention of formation of cancerous melanoma and tumours.

Brightly coloured fruits and vegetables are full of antioxidants which combat cancer cells in the body and hep prevent the formation of tumours.

Both inhibited tumour formation and skin elasticity decreases from sunlight, in an oral test.