Sentences with phrase «in understanding human diseases»

But the technology is already changing human health on another front, by allowing researchers to create genetically modified animals that can aid in understanding human diseases.

Not exact matches

What it does: The role of this bacteria, which is most well - known for causing syphilis and Lyme disease, is still not well - understood in humans.

We must take a clear view of the medical realities of disease and the spiritual realities of sin, but it makes a difference in the pastor's understanding of all human ills that he sees every person as created for a life of love to God and his neighbor.

«These new insights into the complexities of epigenetic regulation are contributing to our basic understanding of this process in human health and disease and gives us new vision for how to go about targeting errors in DNA methylation with innovative drug therapies.»

Cloned primates could help researchers better understand diseases in humans.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

Human tissue grown in the laboratory offers a critical model for understanding the disease process.

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

«It has profound implications for our understanding of human development and physiology, and gives us a remarkable wealth of resources to examine how disturbances of this system might result in diseases such as cancer.»

Buttke is interested in using public interest in personal health as a way to increase support for public green space, and enhancing public understanding of how human actions can drive infectious disease spread through a variety of avenues including school programs, websites, and smart phone apps.

One of the primary goals of genetics over the past decade has been to understand human health and disease in terms of differences in DNA from person to person.

«Once we can build that sort of database for the human organism, it helps us much better understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the Genome Sequencing Center at Washington University in St. Louis.

«The next step in understanding sleep apnea in the future will be to dissect different subtypes of sleep apnea, likely defined by distinct pathophysiological mechanisms which may underlie different outcomes and predisposition to comorbidities,» Cavadas says, «As human life expectancy increases, delaying the onset of age - related diseases becomes critical to our society.»

Further studies of processes in which GTPBP3 is involved will help towards the understanding of human diseases that are linked to mitochondrial DNA expression and to develop new therapies.

«Understanding the evolution of malaria parasites in bats and other animals, and how they fit into the tree of life, is key to understanding this important human diUnderstanding the evolution of malaria parasites in bats and other animals, and how they fit into the tree of life, is key to understanding this important human diunderstanding this important human disease.»

«In many cases we're still learning how these bacteria influence our risk of disease, but understanding the human genetics component is a necessary step in unraveling the mystery,» Knights saiIn many cases we're still learning how these bacteria influence our risk of disease, but understanding the human genetics component is a necessary step in unraveling the mystery,» Knights saiin unraveling the mystery,» Knights said.

Researches are now able to understand for the first time the evolution of these parasites, causing disease in humans and animals.

«Further work in our lab will be aimed at understanding the detailed mechanism of how these proteins regulate editing, in turn providing an inroad to developing therapeutics that modulate editing for the treatment of human diseases.»

«We hope that the results from this study will enable investigators to test the relevance of the maresin pathway in human disease,» said Charles N. Serhan, Ph.D., a researcher involved in the work from the Brigham & Women's Hospital and Harvard Medical School in Boston, Mass. «Moreover, we hope to better understand resolution biology and its potential pharmacology so that we can enhance our ability to control unwanted inflammation and improve the quality of life.»

«This research project is a prime example of how mouse models can help us to better understand cancer diseases in human beings,» says Sabine Harlander.

«Thus, it is clear that further studies must investigate an increasingly complex matrix of cell types and conditions to fully understand the role of human genetic variation in disease.»

«Understanding this previously ignored part of the human genome, its role in human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances,» said Philipp Kapranov, Ph.D., lead researcher at the St. Laurent Institute.

The findings, published in the journal Nature, explain why the human genome is so difficult to decipher — and contribute to the further understanding of how genetic differences affect the risk of developing diseases on an individual level.

In addition to shedding light on how major shifts in body design evolved, the new finding could help scientists better understand certain human diseases and deformitieIn addition to shedding light on how major shifts in body design evolved, the new finding could help scientists better understand certain human diseases and deformitiein body design evolved, the new finding could help scientists better understand certain human diseases and deformities.

NIH gets an extra $ 414 million for Alzheimer's disease research, along with $ 400 million for the BRAIN Initiative, a research project announced by President Obama in 2013 that aims to improve our understanding of the human brain.

To understand why the long - spined urchins have not returned to the reef more than 30 years later, Scripps scientists Katie Cramer and Dick Norris analyzed the amount of fossilized urchin spines that accumulated in reef sediment layers over the past 3,000 years to paint a picture of life on the reef before it was altered from the disease outbreak and human activities such as fishing and pollution.

These individual transcriptomes can be used to define cell types and to understand the functions of healthy and diseased cells in the human body.

«Gaining a better understanding of the functions genes perform in cells, whether plant or animal, is going to help us understand how to diagnose and treat diseases in humans,» says Richard K. Wilson of Washington University.

His research interests include the molecular underpinnings of cervical cancer (including developing genetic screens), the identification of the genetic determinants of quantitative traits in humans, and the application of massively parallel sequencing technology for understanding the genetics of complex disease.

«We are only beginning to understand the role that human - made chemicals play in causing human disease,» said Regnier.

Because of the similarities in ocular anatomy, canine models contribute significantly to the understanding of retinal disease mechanisms and the development of new therapies for human patients.

Her research is at the interface between bioimaging and proteomics, and aims to define the spatiotemporal organization of the human proteome at a subcellular level in an effort to understand how variations and deviations in localization contribute to cellular function as well as disease.

«It's a bit like human disease but in plants, to understand the pathogen and its interaction with the plant allows to develop a functional cure to treat the affected plants» emphasizes the specialist in plant genomics.

However, since the novel genes that were identified, are known to lead to aging - associated diseases in humans, their further analysis seems to be promising for developing new approaches to understand and possibly cure these diseases and to contribute to a long life and healthy aging in humans — in a way, long - lived rodents do.

At the Rockefeller meeting, an important impetus behind the big ambitions — the quest to decipher the gamut of human brain diseases that are still incredibly poorly understood — was evident in the room.

«Now that we have a better understanding of how an animal is built we can get some way closer to knowing how the human body works in health and disease,» says John Sulston, director of the Sanger Centre at the Wellcome Trust Genome Campus, Cambridgeshire, England.

Conservation work to defeat the disease has including removing infected individuals from the population and new research in Evolutionary Applications explains how this gives us a unique opportunity to understand how human selection alters the evolution of cancerous cells.

Understanding how the human immunodeficiency virus (HIV) reproduces itself is crucial in the effort to fight the disease.

«NGS technologies have vastly improved our understanding of the human genome and its variation in diseases such as cancer,» said Ken Chen, Ph.D., assistant professor of Bioinformatics and Computational Biology and co-author of the Nature Methods article.

The Structural Genomics Consortium at the University of North Carolina at Chapel Hill (SGC - UNC), in partnership with the DiscoverX Corporation, has reached the milestone halfway point in its development of the Kinase Chemogenomic Set, a potent group of inhibitors which allow deeper exploration of the human kinome, a family of enzymes critical to understanding human disease and developing new therapies.

«In the future, such efforts could allow us to much better understand human - microbiome interactions, model malnutrition disorders and inflammatory diseases of the gut, and perform personalized drug testing,» said co-first author Alessio Tovaglieri, a Graduate Student at the Department of Health Science and Technology at ETH Zurich in Switzerland, who performs his thesis work on Ingber's teaIn the future, such efforts could allow us to much better understand human - microbiome interactions, model malnutrition disorders and inflammatory diseases of the gut, and perform personalized drug testing,» said co-first author Alessio Tovaglieri, a Graduate Student at the Department of Health Science and Technology at ETH Zurich in Switzerland, who performs his thesis work on Ingber's teain Switzerland, who performs his thesis work on Ingber's team.

By building this selective set of compounds and making it freely available, UNC - Chapel Hill and its partners are offering the scientific community a better understanding of the roles the kinome plays in human disease and the ability to collaborate on the discovery and advancement of new therapies.

«Aberrant splicing in humans may lead to various complex diseases and also underlies the development of some forms of cancer and the onset of neurodegenerative diseases, so a better understanding of the process can add important information for our fight against these diseases.»

Overall, this work illustrates that better understanding the basic biology of the immune system in preclinical models may open up a window for the development of novel treatments for human autoimmune disease.

«Our findings also have important implications for mitochondrial diseases in humans, because this research significantly advances our understanding of how mitochondrial DNA mutations affect individuals and populations, and provides a potential mechanism to explain how different genetic variants may affect health,» Dr Rollins said.

Richard Lindsay, a PhD student who worked on the research team, added: «Our findings are of central importance in understanding how microbial infections evolve, but also have wider significance for the treatment of cancer and the therapeutic control of disease in humans, animals and plants.»

Because many rabbit genes are similar to their human counterparts, manipulating disease genes in rabbits, like the one responsible for cystic fibrosis, may permit researchers to track the disease's onset and better understand what goes awry.

This discovery plays a primordial role in understanding immune system diseases in humans.

Knowing how cells exert force and sense mechanical feedback in their microenvironment is crucial to understanding how they activate a wide range of cellular functions, such as cell reproduction, differentiation and adhesion — basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects of human health and disease.

Scientists are only beginning to understand what role the billions of microbial cells colonizing the human gut play in diet and disease.