Not exact matches
But when they broached the idea of developing such a
vaccine with drug
companies, nearly all of them said, «No, thank you very much, but we're not interested,» recalls Schiller
in a Lasker Foundation interview.
The
company first offered this UberHEALTH option two years ago, administering flu shots
in Boston, New York, and Washington, D.C. Uber did it again last year, offering
vaccines in more than 35 cities — they cost $ 10, but up to 10 people could be vaccinated with each request.
Further gains were mitigated, however, by continued fallout
in the
company's top - grossing PREVNAR
vaccine franchise -LRB--8 %), overseas generic erosion on ENBREL -LRB--20 %), and weak domestic sales of fading blockbuster VIAGRA -LRB--17 %).
The
company also has
vaccines in clinical development for cholera (Vaxchora), anthrax, HIV and hepatitis A.
Janssen Inc. is one of the Janssen Pharmaceutical
Companies of Johnson & Johnson, which are dedicated to addressing and solving some of the most important unmet medical needs
in oncology, immunology, neuroscience, infectious diseases and
vaccines, and cardiovascular and metabolic diseases.
Although the
company's efforts
in this area are still
in the early - stage phase, an effective flu
vaccine could be worth up to $ 3 billion per year
in sales, according to Research and Markets.
The complete wipeout of Novavax's elderly adult RSV
vaccine hasn't deterred the
company from pursing this multibillion - dollar indication
in the least.
If successful, the
company's experimental RSV F
vaccine could become part of the standard of care for expecting mothers
in the United States, and perhaps even abroad.
If the data looks good, it's likely the
company's RSV
vaccine could be
in regulators» hands by 2017.
This is the same
company that was fined earlier this year nearly a million dollars for the
vaccine related deaths of 14 babies
in Argentina.
Democrats and liberal groups have successfully attacked Heck on social security privatization and a vote
in the state Senate against a bill that would have required insurance
companies to cover a
vaccine for cervical cancer.
Germany - based biotech
companies CureVac and BioNTech are also testing several mRNA - based cancer
vaccines in clinical trials.
The British - American
company Acambis, based
in Cambridge, Mass., and Cambridge, England, has obtained the license to start production of the
vaccine.
At least 12
companies and 17 governments are developing pre-pandemic influenza
vaccines in 28 different clinical trials that, if successful, could turn a deadly pandemic infection into a nondeadly one.
One such pseudoscientific claim was that microcephaly is caused by the MMR
vaccine and pharmaceutical
companies are blaming Zika virus
in order to profit from selling Zika
vaccines.
In October he started a new
company that will work with the pharmaceutical giant Novartis to create next - generation flu
vaccines.
The swine flu pandemic was a hoax: scientists, governments and the World Health Organization cooked it up
in a vast conspiracy so that
vaccine companies could make money.
The team claims its work, funded by Tonix, a pharmaceutical
company headquartered
in New York City, could lead to a safer, more effective
vaccine against smallpox.
The method is relatively new, but far bacteria - based
vaccines have proven effective: A seasonal flu
vaccine produced by VaxInnate successfully protected humans
in clinical trials, and the
company's recently tested swine flu
vaccine immunized mice against the virus.
In December 2006, Bioniche Life Sciences, a Canadian pharmaceutical
company, was granted a license by the Canadian Food Inspection Agency to distribute the
vaccine to cattle veterinarians there.
The
company's initial
vaccine formulation targets Rift Valley Fever, found
in Africa and the Arabian Peninsula.
Last January, as new H1N1 flu infections were trailing off
in the Northern Hemisphere, accusations began to fly that the World Health Organization's declaration of a pandemic
in the spring of 2009 had served mainly to line the pockets of pharmaceutical
companies making
vaccines and the drug Tamiflu.
The
company plans
in October to conduct a separate test specifically to study the seasonal flu
vaccine's effectiveness among 480 elderly participants (a demographic often encouraged to get seasonal flu shots), and Phase III efficacy trials across a larger set of demographics are scheduled to begin early next year.
The
vaccine was most effective against H3N2, increasing antibody titers (a measure how much antibody is produced after vaccination) fourfold
in more than 81 percent of who received it, according to the
company.
Novavax is not the only
company developing VLP - based
vaccines, although it is ahead of the game
in the category of flu
vaccines.
The
company claims its VLP approach allows it to manufacture a
vaccine to match a particular virus strain
in about three months.
In addition,
vaccine - makers that use eggs can not begin developing new
vaccines that target new virus strains until the U.S. Centers for Disease Control and Prevention (CDC) creates a live - virus reference strain for these
companies to work with, a process that could take several weeks.
The
company's
vaccine approach
in both cases is to use viruslike particles (VLPs) containing surface proteins that make the VLPs resemble a virus, thereby eliciting the proper immune response — even though the VLPs lack the genes needed to replicate themselves.
The
vaccine is given
in three infusions; each costs $ 31,000, for a total treatment tab of $ 93,000, the
company said today.
So he joined GSK
Vaccines in 2010, as a molecular biologist
in the
company's Antigen - Specific Cancer Immunotherapeutic program, which aims to harness the immune system for the development of well - tolerated cancer therapies.
The BMJ also notes that three scientists who were involved
in the preparation of a 2004 WHO document, WHO Guidelines on the Use of
Vaccines and Antivirals during Influenza Pandemics, had received payments from pharmaceutical
companies, including research funding, or consultancy or speaker fees.
Friedman and colleagues are now
in discussions with pharmaceutical
companies to move the
vaccine, or an optimized version of it, into initial clinical trials.
«A key question will be whether the pharmaceutical
companies, which had invested around $ 4 billion
in developing the swine flu
vaccine, had supporters inside the emergency committee, who then put pressure on WHO to declare a pandemic,» says the article
in the BMJ.
And Indian
vaccine companies, which can produce
vaccine more cheaply, hope to make their own IPV not from wild polio, which is risky to handle, but from the weakened virus used
in OPV.
Companies in China and India that had no plans to add IPV to routine childhood
vaccines two years ago now do.
The
company has begun two safety trials
in the US,
in people at low risk of infection and
in people at high risk, and says it has evidence that the
vaccine is safe.
No data on the
vaccine have yet been published and some AIDS researchers have privately expressed fears that the
company is moving too fast by testing the
vaccine in a developing country.
Researchers at MedImmune, a Maryland - based biotech
company, and at Washington University
in St. Louis whipped up two separate
vaccine formulations
in the hope that at least one would successfully target an «adhesion» molecule called Filamentous H, or FimH, present on E. coli.
Yet
vaccine companies have little incentive to build expensive new factories to make a product that will mostly be used once wild polio is gone — maybe
in three years, maybe 10 — and then only for another five years or so.
Already scientists at Human Genome Sciences
in Rockville, Maryland — a biotech
company affiliated with Venter's research institute — have begun working on a more effective
vaccine against Haemophilus.
In order to promote their patented drugs and
vaccines against flu, pharmaceutical
companies have influenced scientists and official agencies, responsible for public health standards, to alarm governments worldwide.
BRUSSELS — CureVac, a
company based
in Tübingen, Germany, that develops RNA - based
vaccines and therapies, has won a $ 2 million prize awarded by the European Commission to stimulate new
vaccine technologies that might help the developing world.
He has long advocated global cooperation
in the surveillance of circulating flu viruses to spot emerging new strains so public health officials could plan a response and drug
companies could get a head start
in making
vaccines.
An expert jury says that the
company's research could lead to a new generation of
vaccines that don't need refrigeration — a massive benefit
in many poor countries where power and equipment are
in short supply.
In its application, the
company showed how stable RNA - based
vaccines are.
Jury member Penny Heaton, director of
vaccine development at the Bill & Melinda Gates Foundation, said CureVac's RNA technology had «the potential for a large and positive impact on public health,»
in a statement released by the
company on 10 March.
Several research institutions and
companies have
vaccine and drug candidates nearly ready to test, but until now a mouse model — a critical stage
in preclinical testing — has not been available.
The Swiss - based pharmaceutical
company said that it had made 10 liters of
vaccine that it will use
in pre-clinical studies and maybe early clinical trials.
In a press release issued today, the
company said it has yet to receive a «seed stock» from the World Health Organization to manufacture the
vaccine and that upon receipt of the stock it will require 4 to 6 months to produce the
vaccine.
In November 2012, the
company also showed, along with scientists from the Friedrich Loeffler Institute, that the technology could lead to a new generation of flu
vaccines.