Sentences with phrase «in ventral tegmental area»

In the brain, the ghrelin receptor is located in the the hypothalamic ventromedial nucleus and arcuate nucleus, as well as in ventral tegmental area dopamine neurons projecting to the nucleus accumbens.

In the brain, they are located in the hypothalamic ventromedial nucleus and arcuate nucleus, as well as in ventral tegmental area dopamine neurons projecting to the nucleus accumbens.

Dopamine (DA) neurons are found in the ventral tegmental area (VTA) and the substantia nigra pars compacta (SNc).

Here we used shRNA to model Shank3 insufficiency in the ventral tegmental area of mice.

DJ -1-deficient mice show less TH - positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments

For example, he demonstrated that nicotine - induced formation of the endocannabinoid 2 - AG in the ventral tegmental area is sensitized following chronic nicotine exposure.

Through the combined use of in vivo microdialysis and behavioral and neuropharmacological techniques, his early work characterized the role of serotonin and its signaling via serotonin - 1B (5 - HT1B) receptors in the ventral tegmental area, nucleus accumbens, and ventral pallidum in the rewarding actions of cocaine and ethanol.

«Resilient mice overcome this change by counteradapting their gene expression [the suite of genes that act on the nucleus accumbens that are either turned on or off] to clamp down the levels of activity in the ventral tegmental area.»

12 Can't Get Enough of Your Love: Dopamine is produced in the ventral tegmental area of the brain, the same region affected by addictive drugs like cocaine.

The blunted dopamine signaling to ethanol arose due to changes in the circuitry in the ventral tegmental area, the heart of the brain's reward system.

Mice in booze camp In the new study, performed on adolescent male mice, ethanol alcohol exposure seemed to enhance synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathway.

Looking inside the brains of animals exposed to chronic social defeat stress, the scientists observed hyperactive firing of neurons in the ventral tegmental area (VTA), a critical part of a reward circuit.

Not exact matches

To regulate mood, the prefrontal cortex acts as a pacemaker to coordinate the actions of the amygdala, which governs stress responses, and the ventral tegmental area, which plays a role in the brain's reward circuitry.

Drugs of abuse impact the ventral tegmental area (VTA) of the brain, which is rich in dopamine neurons.

Glutamate indirectly activates the substantia nigra and ventral tegmental area, which contain cells whose axons release dopamine in the hippocampus.

Between - group analysis of phase 2 demonstrated a significant activation cluster in the ipsilateral posterior insula (pIns) in group P. Using the pIns as a seed region the PPI analysis yielded a significant enhanced coupling to the midbrain (periaqueductal grey / ventral tegmental area) after analgesia onset in group A only.

Neuroscientists know that a particular brain structure, the ventral tegmental area, or VTA, is the origin of numerous dopamine - secreting nerve fibers that run in discrete tracts to many different parts of the brain.

More specifically, in a 2012 review of the love research literature Lisa Diamond and Janna Dickenson, psychologists at the University of Utah, found romantic love is most consistently associated with activity in two brain regions — the ventral tegmental area (VTA) and the caudate nucleus.

This aberrant 2 - AG signaling reduces inhibitory GABAergic signaling at ventral tegmental area dopaminergic synapses, resulting in enhanced dopamine cell excitability and excessive dopaminergic responses to nicotine.

Upon intake of alcohol, the absence of the RASGRF - 2 impaired the activity of dopamine - releasing neurons in a region of the brain called the ventral tegmental area (VTA) and prevented the brain from releasing dopamine, and hence any sense of reward.

Previous research in the laboratory of Daniel McGehee, PhD, neuroscientist and associate professor in the Department of Anesthesia & Critical Care at the Medical Center, discovered that nicotine could promote plasticity in a region of the brain called the ventral tegmental area (VTA).

«Love triggers the parts of the brain associated with reward,» van der Walt says, «in neuroscience terms this is the caudate nucleus and the ventral tegmental, areas of the brain that release the neurotransmitter dopamine.»

In the earlier stages of love, other brain areas such as the caudate nucleus and the ventral tegmental areas become active.