Sentences with phrase «in vesicle trafficking»

During a brief post-doctoral fellowship with Harvey Lodish at the Massachusetts Institute of Technology Rothman learnt to work with viruses and cell - free systems — thus acquiring skills that would later prove invaluable for identifying molecules involved in vesicle trafficking.

In fibrosarcoma and neuroblastoma cells, huntingtin shows discrete punctate, perinuclear localization overlapping largely with the trans - Golgi and cytoplasmic clathrin - coated vesicles, implicating huntingtin in vesicle trafficking.

A protein that transports the simple chemical choline plays a major role in vesicle trafficking, ion homeostasis, and growth and development in plants, according to two new studies publishing 28 December in the open - access journal PLOS Biology, by Dai - Yin Chao of the Shanghai Institutes for Biological Sciences, China, and Sheng Luan of the University of California, Berkeley, USA, and co-workers.

CTL1 mutation also altered the distribution of ion transporters, which, combined with previous work localizing CTL1 to the trans - Golgi network, led the authors to investigate whether CTL1 played a direct role in vesicle trafficking.

Not exact matches

25 October 2013: The 2013 Nobel Laureates who published in Science include, for Medicine, James E. Rothman, Randy W. Schekman and Thomas C. Südhof for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells.

CTL1 is also found in animal cells, Chao noted, and thus the study concluded that «characterizing CTL1 as a new regulator of protein sorting may enable researchers to understand not only ion homeostasis in plants but vesicle trafficking in general.»

«A new regulator of vesicle trafficking in plants: Choline transporter regulates ion homeostasis and plant growth and development.»

Enrich points out that «in the cell, cholesterol controls the trafficking of vesicles, which are responsible for transporting integrins to cell surface.

He is presently studying the role of specific defects in apical vesicle trafficking in the etiology of neonatal diarrhea syndromes in human.

In her research she uses C. elegans and mammalian cells to study dense core vesicle trafficking and Gq signaling in neuronIn her research she uses C. elegans and mammalian cells to study dense core vesicle trafficking and Gq signaling in neuronin neurons.

Vesicle Traffic Late in the Secretory Pathway Little is known about the mechanism of sorting and packaging of secretory proteins that transit from the Golgi complex to the cell surface.

Others including Randy Schekman had discovered NSF to be important for vesicle trafficking and secretion in yeast, leading Rothman to argue that these proteins are involved in vesicle fusion in every cell of the animal kingdom — a universal mechanism for secretion.

In differentiated adipocytes GFP - tagged ARL15 localized predominantly to the Golgi with lower levels detected at the plasma membrane and intracellular vesicles, suggesting involvement in intracellular traffickinIn differentiated adipocytes GFP - tagged ARL15 localized predominantly to the Golgi with lower levels detected at the plasma membrane and intracellular vesicles, suggesting involvement in intracellular traffickinin intracellular trafficking.