While studying a group of women at risk of HIV in Mombasa, Kenya, senior author Overbaugh and colleagues noticed that one woman carried an AIDS virus that was easily
inactivated by antibodies.
Not exact matches
The flu vaccine works
by exposing the body to parts of
inactivated flu from the three major different types of flu that infect humans, prompting the immune system to develop
antibodies against these viruses.
Previous laboratory studies have shown that
antibodies produced
by the human immune system to fight dengue virus can also interact with Zika virus (ZIKV) without
inactivating it.
They also rally forces
by docking to the CD40 receptor of B cells, stimulating these cells to manufacture potent immunoglobulin G (IgG)
antibodies that can
inactivate foreign proteins.
By 2000, Korman and Lonberg had used this approach to create a human
antibody, ipilimumab, that binds and
inactivates CTLA - 4.