Not exact matches
In cancer, these
switches inappropriately activate or silence important
genes, such as those that regulate cell growth and life cycle, ultimately leading to tumors.
Previous studies of genetic alterations in lymphoma and lung cancer have found that certain genetic mutations — specifically when part of a
gene breaks off and gets fused to another — can
inappropriately switch on ALK, driving cancer cells to grow and divide.
They produce promoters, chemicals that can
switch on our own
genes inappropriately.