Not exact matches
Their antioxidant and anti-inflammatory activities are largely due to their abilities to scavenge the reactive oxygen species (ROS) and improvement of antioxidant status by attenuating the activity of NF - κB and suppressing the expression of several inflammatory cytokines and chemokines
including monocyte chemotactic protein - 1 (MCP - 1), nitric oxide synthase,
cyclooxygenases, lipoxygenases, cellular adhesion molecules, tumor necrosis factor and interleukins.
These acids decrease the body's production of a long list of pro-inflammatory biochemicals,
including the same ones targeted by most NSAIDs —
cyclooxygenase (COX 1 and 2).
As I illustrated above, arachidonic acid is processed by the enzyme
cyclooxygenase (COX) to produce pro-inflammatory signaling molecules called eicosanoids,
including leukotrienes, prostaglandins, and thromboxanes.
It is mainly contained in the seeds and has been shown to inhibit
cyclooxygenase - 2, an inflammatory protein related to a number of health conditions,
including Benign Prostatic Hyperplasia (BPH).
As mentioned previously, ginger properties
include anti-inflammatory actions that stem from a group of compounds called gingerols, which work by inhibiting the prostaglandin - biosynthesizing enzyme, known as PH synthetase or
cyclooxygenase (COX).
In the case of
cyclooxygenase (COX), it stimulates cells to produce several substances,
including prostaglandins, after the cells are damaged.