Sentences with phrase «include gene sequencing»

More studies include gene sequencing and look at the entire genome instead of just one or two genes.

Bioinformatic approaches to the analysis of genetic variability and complex genotype - phenotype relationships will moreover include gene sequence and database analyses, measures of association of haplotypes / genotypes with phenotype, clustering procedures, neuronal networks, fuzzy and other techniques in pattern recognition, similarity measures for discrete patterns (e.g., gene sequences, structures, functions), logistic regression methods, and a spectrum of other techniques.

Not exact matches

A separate genetics adviser will review, support and identify potential linkages in the genetics component of methane mitigation, including genomics (work on recombinant DNA and gene sequencing) and genetic interaction with environment.

The goal is to identify the genes necessary to install C4 photosynthesis in rice through different approaches, including genomic and transcriptional sequence comparisons and mutant screening.

In addition both constructs contain the constitutive Ubi promoter and nos T terminator, the bar gene conferring herbicide tolerance and may contain further sequences of bacterial origin including the neomycin phosphotransferase (nptI) selectable marker gene.

In fact, the MESA researchers had included 46 different variants of the gene in their sequencing database.

In the new study, the researchers sequenced the entire genome of mice that had undergone CRISPR gene editing in the team's previous study and looked for all mutations, including those that only altered a single nucleotide.

However, the results of more recent phylogenetic analyses, derived from comparisons between sequences of specific genes and of whole genomes, seemed to point to Ctenophora as the first group that parted company with the lineage from which the rest of the animal kingdom (including sponges) evolved.

Using RNA sequencing, the researchers found multiple genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a normal placenta.

They processed data relating to genetics, including DNA sequences, and to gene expression, as well as epigenetic features — chemical reactions that influence genome functioning and hence phenotype by activating and deactivating genes.

They identified 60 genes that exhibited convergent evolution in CAM species, including convergent daytime and nighttime gene expression changes in 54 genes, as well as protein sequence convergence in six genes.

Near each Crispr sequence are genes for a variety of Cas (Crispr - associated) enzymes, including Cas9.

Surprises include the discovery of about 20 eukaryotic genes; other bacteria that have been sequenced have had few, if any, such genes.

The researchers then compared the expression of all genes in six parts of the brain of the two bird species using state - of - the - art molecular techniques, including next - generation sequencing — the first time these tools have been used to find brain properties related to innovation and problem - solving in wild birds.

They also ruled out other possibilities, including the gene spontaneously mutating back to the normal form, the existence of more than two copies of the hothead gene, or closely related DNA sequences providing a template for repairs.

Using a novel combination of technologies, including trio exome sequencing of patient / parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome — a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

To trace the gene's evolutionary history in humans, the team sequenced a segment of DNA that includes ACTN3 in 96 people from Europe, Asia, or Africa.

In addition, it binds to the promoter sequences (dark blue) of specific target genes including mitochondrial fission process 1, MTFP1.

Although the gene sequences were not identical to the Mikovits - Ruscetti XMRV gene sequence reported in Science, they were so close Lo believed he had found genetic variants of a single MLV - like virus species that likely included XMRV.

For this reason, their finding — that nearly half of the unmapped sequences contained in available genomic reference libraries, including many protein - coding genes, were located in the centromeres — was unexpected.

An international team of scientists has sequenced the genome of an octopus, bringing researchers closer to discovering the genes involved in the creature's unusual biology, including its ability to change skin color and texture and a distributed brain that allows its eight arms to move independently.

Computational genomics includes: bio-sequence analysis, gene expression data analysis, phylogenetic analysis, and more specifically pattern recognition and analysis problems such as gene finding, motif finding, gene function prediction, fusion of sequence and expression information, and evolutionary models.

Noncoding DNA includes stretches called enhancers, short sequences that help control a target gene.

Matches between new genes from other species, including mammals, and these E. coli sequences have often helped researchers pin a name and function on their discoveries.

The BBSRC - funded ARK - Genomics facility — which is part of Edinburgh Genomics at the University of Edinburgh — provided a substantial body of sequence data, including information on which genes are expressed in a spectrum of 40 different tissues.

Many of these repeats, including some genes, appear as back - to - back series of the same repeated sequence or as long palindromes which, like the word «racecar,» read the same forward and backward.

A family of neuropeptide genes which includes the gene encoding ELH along with two additional genes encoding the A and B peptides thought to initiate the egg - laying process has been isolated and their nucleotide sequence has been determined.

To identify genetic changes likely to be responsible for the giraffe's unique characteristics, including sprints that can reach 37 miles per hour (60 km / h), Cavener and Agaba compared the gene - coding sequences of the giraffe and the okapi to more than forty other mammals including the cow, sheep, goat, camel, and human.

The shared sequence included a gene called CNGA3, they report in the July issue of Nature Genetics.

While normal HD genes include up to 40 copies of the DNA sequence CAG, the mutated version is crammed with many more copies.

In the last four years scientists have cloned and sequenced many genes carrying defects that cause disease, including those responsible for Fragile X linked mental retardation, different forms of muscular dystrophy, and most recently Huntington's disease.

And when they sequenced Sputnik's genome, they found its small ring of DNA contained genes from three different viral families, including Mamavirus.

These differences include widespread sequence variation, extra copies of genes, and massive, complex rearrangements.

To develop fluorescent in situ sequencing, scientists first fix in place thousands of RNAs — including working copies of genes called messenger RNAs — in cells, tissues, organs or embryos.

Her team analysed the DNA sequence of the gene TAS1R3, which codes for a sweet taste receptor, in 51 primate species, including humans.

The researchers» next step is to use the genomic data they collected from the families — including full genome sequences and gene expression data — to begin identifying the specific genes that contribute to risk for bipolar disorder.

Canadian researchers conducted a pilot study with 20 newborns to determine the effectiveness of a targeted next - generation sequencing panel that included all 4813 genes currently known to be associated with rare diseases.

Future additions to the RM collection may include whole genomes from persons with Hispanic, African and mixed ancestries, as well as a set containing sequenced genes of both malignant tumor and normal cells from the same individual.

Other mammals, including humans, also have a gene with nearly the same sequence and function as SIRT1.

As the name suggests, ecRNA partially overlaps with a gene sequence that produces messenger RNA; but it also includes RNA sequences from DNA beyond the gene boundary.

Ever since the sequencing of the first genomes from eukaryotes — a group that includes yeast and humans — scientists have wondered why most of these creatures» DNA is devoid of genes.

This includes how subtle changes in gene sequences can impact the expression of encoded proteins through mechanisms including codon bias, mRNA stability, and translation initiation.

Much of what they sequenced turned out to be microbial contaminants, as expected, but 6 percent was cave bear nuclear DNA, including bits of 21 genes.

The branch uniting the fungi and animals is well - supported based on a number of molecular phylogenetic datasets, including the nuclear small subunit ribosomal RNA gene (Wainwright et al., 1993; Bruns et al. 1993), unique and shared sequence insertions in proteins such as elongation factor 1α (Baldauf and Palmer, 1993), entire mitochondrial genomes (Lang et al., 2002), and concatenated protein - coding genes (Steenkamp et al., 2006).

«Such analyses could complement current risk assessment strategies of emerging influenza viruses, including viral genome sequencing and screening for alterations in known viral virulence genes.»

The atlas now also includes RNA transcript data for 27 of these organ - specific tissues using next generation sequencing, providing a tissue distribution map of both protein and gene expression.

We offer a wide range of services, including capillary sequencing and genotyping, Illumina microarray - based gene expression profiling and genotyping, and next - generation sequencing (NGS).

For more information about SAM, including a tool for getting optimized guide sequences for activating any human gene, go to http://sam.genome-engineering.org/.

Details that can be included are biochemical reactions; gene regulatory networks; genetic interactions; proteins, small molecules, DNA, RNA, complexes and their cellular locations; complex assembly and transport; post-translational protein modifications; citations; experimental evidence; and links to other databases e.g. protein sequence annotation.

The ability of Nanopore sequencing to define the complete exonic structure of CACNA1C allows us to identify known and novel gene isoforms, including novel exons and multi-exonic skipping events and their expression across multiple brain regions.