Sentences with phrase «include gene transfer»
Studies can also include gene transfer systems such as transformation, conjugation and transduction.
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These include genes from plants and organisms unrelated to rice that could not be transferred using other breeding methods.
Subsequent procedures included mammalian somatic cell nuclear transfer, cell fusion, induction of pluripotency by ectopic gene expression, and direct reprogramming.
Research areas include species for comparative research; phenotypic characterization; fitness, genome stability and lateral gene transfer; control of organismal traits; monitoring and surveillance; modeling and standardization of methods and data.
DNA analyses of the Oaxaca corn revealed several signs of gene transfer from transgenic plants, including a gene of Bacillus thuringiensis (Bt), a bacterium that produces a toxin lethal to common pests.
Beginning with the Nazi Doctors» Trial at the 1946 Nuremberg Trial (1), coverage includes publication of Henry Beecher's «Ethics and Clinical Research» (2), The New York Times exposure of the public health service syphilis study in Macon County, Alabama (the infamous «Tuskeegee case»)(3), the University of Pennsylvania / Gelsinger gene transfer case, and The Washington Post series on international clinical drug testing abuses (4).
They say that genes from wasps have been transferred to several butterfly species, including the monarch, by symbiotic viruses used as biological weapons by parasitic wasps.
This sort of horizontal gene transfer across families of bacteria — other relatives include Samonella, Shingella and the plague - causing organism Yersinia — marks a significant finding, Blattner notes.
The team discovered that the pattern of differences in genome organization between various individuals of the same species indicates that the bacteria transfer DNA, including whole genes, back and forth.
Using a novel technique to genetically modify T cells for adoptive transfer, Carl June, Michael Kalos, David Porter, Bruce Levine, and colleagues at the University of Pennsylvania School of Medicine achieve clinical responses in patients with chronic lymphocytic leukemia, including two complete, durable (one year) clinical responses, accompanied by in vivo expansion and long - term functional persistence of gene - modified cells.
Contribution to the understanding of how the evolution of gene families relates to functional divergence, including the fate of duplicated genes, horizontal transfer and interspecies hybridization, as well as the characterization of the ancestral patterns of evolution among archosaurs, and the discovery of the late acquisition of mitochondria in eukaryotes (Gabaldón's group, Science 2014, PLoS Biology 2015, PLoS Genetics 2015, Nature 2016).
In an impressive example of horizontal gene transfer, the whitefly has acquired 142 genes from bacteria or fungi, including some coding for enzymes that break down foreign chemicals.
The latest developments in CAR - T translation and manufacturing including alternate gene transfer methods to deliver CARs; novel gene editing approaches, advances in CAR design to improve safety and efficacy, and progress in creating an «off - the - shelf» allogeneic CAR - T therapy.
Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), are known to be vulnerable to apoptosis upon various technical manipulation, such as single cell dissociation, freezing and thawing, etc., which hinder their use for clonal isolation in gene transfer, differentiation and FACS cell sorting.
Specific activities include optimizing the conduct and oversight of gene transfer research, updating and interpreting biosafety policies under the NIH Guidelines Involving Research with Recombinant and Synthetic Nucleic Acids, providing critical input on governmental policies regarding dual use research, the NIH Stem Cell Registry.
Others were unanticipated, including significant differences in expression levels among genes involved in fundamental cellular processes such as ribosomal biogenesis, transfer RNA processing, and Notch - signaling — part of a complex system of communication that governs basic cellular activities and coordinates cell actions.
New coding genes can arise in genomes through several processes, including gene duplication, gene fusion, de novo formation from non-coding DNA, or lateral gene transfer (LGT) from another species.
Her research initially focused on the identification and characterization of juvenile dilated cardiomyopathy in Portuguese water dogs and has led to several ongoing studies, including most recently the evaluation of various candidate genes for use in a therapeutic gene transfer approach to improve cardiac function in failing hearts.
Introduced species means any species (including but not limited to any of its biological matter capable of propagation) that is non-native to the ecosystems of the Sanctuary; or any organism into which altered genetic matter, or genetic matter from another species, has been transferred in order that the host organism acquires the genetic traits of the transferred genes.
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