Her research interests during her residency
included novel therapies for the treatment of canine pulmonary hypertension (endothelin) antagonists as well as echocardiographic evaluation of the heart's «pump» function in the setting of mitral valve disease.
Not exact matches
This has motivated
novel cardiotherapeutic strategies to repair and regenerate heart muscle,
including human mesenchymal stem cell (hMSC)
therapy.
This
novel approach may have ramifications for other inflammatory diseases
including rheumatoid arthritis and psoriasis, as well as for other biologic
therapies (such as Humira) used to treat these conditions.
«A better understanding of how inflammation affects stem cells and other components of tissue will revolutionize our understanding of many diseases,
including cancer, and likely lead to
novel therapies,» Naik says.
An international team of hematologists
including Guy Young, MD, of Children's Hospital Los Angeles, has found that in patients with hemophilia A with inhibitors, a
novel therapy called emicizumab, decreases incidence of bleeding episodes by 87 %.
We provide access to the latest medicines and technology, as well as the most advanced clinical trials
including novel personalized targeted
therapies including precision medicine and immunotherapy - some that are only offered at NCI - designated Comprehensive Cancer Centers like ours.
His major research interests are human neuroanatomy and neuropathology and the use of animal models to test
novel therapies for neurodegenerative diseases
including Alzheimer's disease.
We are currently developing small molecule Nav1.1 activators that increase Nav1.1 currents and interneuron - dependent gamma oscillations in vitro and in vivo to develop
novel therapies for conditions with impaired interneuron function,
including AD and Dravet syndrome.
Major focus areas
include human genome interpretation and genetic dissection of
novel rare diseases, predictive genomic signatures of response to
therapy — especially cancer
therapy, and
novel sequencing - based assays as biomarkers of disease.
Other areas of research
include designing
novel therapies based on molecular pathways and identifying predictive biomarkers in patients to design personalized, targeted
therapies.
The latest developments in CAR - T translation and manufacturing
including alternate gene transfer methods to deliver CARs;
novel gene editing approaches, advances in CAR design to improve safety and efficacy, and progress in creating an «off - the - shelf» allogeneic CAR - T
therapy.
These combined clinical and laboratory resources accelerate the development of
novel therapeutics,
including immune
therapies — resulting in optimized, personalized cancer treatments.
These could
include targeted probiotic
therapy,
novel vaccines or vaccine strategies and new therapeutics to treat LRTI.
Many of these strategies are used to then test
novel medications (
including herbal preparations) or
therapies (
including electroacupuncture) for drug and alcohol abuse.
More than a dozen experimental clinical
therapies and vaccines have been developed from research from the Weiner laboratory,
including the first Zika vaccine in clinical trials, as well as a
novel immunotherapy for HPV - associated cancer and precancer.
The approach is to use clinically relevant tumor models such as patient - derived xenografts (PDXs), as well as humanized and immunocompetent transgenic tumor - bearing mice to design rational combinations of
novel and emerging cancer
therapies,
including tumor - targeting and immune - stimulating
therapies, to ultimately improve treatment outcomes for cancer patients.
As the Director of the Early Phase Clinical Trials Program at Roswell Park, I am responsible for developing
novel therapies for many types of cancer,
including melanoma.
Access over 20 podcasts recorded by conference keynotes, chair people, session moderators, and speakers who offer their expert perspective and commentary on the scientific trends impacting ADC's, Bioconugates,
Novel Therapies, Cell
Therapies including Upstream Processing and Downstream Processing, Biosimilars and Formulation strategies for Biologics.
It
includes the Rheumatology Clinical Research Unit, which currently is conducting clinical trials of
novel therapies for lupus, rheumatoid arthritis, IgG4 - related systemic disease and osteoarthritis.
She is interested in translating
novel research discoveries,
including regenerative medicine and lubricin
therapy, to equine clinical patients with musculoskeletal disease.
She was involved in multiple clinical trials
including the development of a
novel pain assessment tool in dogs undergoing radiation
therapy.
Dr. Thomovsky's research interests
include rehabilitation in the post-operative neurologic patient,
novel anti-convulsant
therapies and movement disorders.
Research Interests Critical care of polytrauma patients, troponin as a biomarker in traumatic myocarditis, the application of Continuous Renal Replacement
Therapy (dialysis) for companion animals with acute kidney failure, advanced therapeutic approaches to immune mediated hemolytic anemia, and
novel laboratory assessment of coagulopathies (
including thromboelastography and platelet aggregometry).
Studies
include the investigation of chemotherapeutic agents,
novel chemotherapy dosing regimens, and imaging of tumor patients as it relates to radiation
therapy.
In the downstairs gallery, a spectacular array of
novel ways of living encompasses nature, culture and the human self in the form of a futuristic garden by the London collective Wayward Plants, a practising potter's studio conceived by the American artist Theaster Gates, and Pedro Reyes» Sanatorium, a functioning wellbeing centre where visitors can experience
therapies that
include hitting a dummy whose face is a balloon on which you have drawn the face of the person you feel most oppressed by.
New treatments are being tested to tackle the crippling difficulties of vertigo,
including a clinical trial of prosthetic ear implants and ear gene
therapy, with initial work revealing
novel aspects of brain anatomy linked to balance which could be used as targets for future treatments.
Treatment Approach: Ken employs Client - centered, Cognitive - Behavioral, Insight, Interpersonal, and Family Systems
therapies often coupled with client - appropriate psycho - education that may
include biographies /
novels, workbooks, and movies.