The main mechanism
includes phagocytosis of macrophages which play a critical role in nonspecific defense (innate immunity) and, moreover; they have a role as antigen presenters which also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune cells such as lymphocytes.
Not exact matches
Blocking the mechanisms involved in other methods of cell death
including apoptosis and
phagocytosis did not disrupt the process, confirming that entosis operates in a different way.
These
include: 1) live viral vaccine neutralization by maternal Abs, 2) Ab feedback mechanisms, 3) elimination of vaccine - antigen / maternal Ab immune complexes by
phagocytosis, 4) inhibition of B cell responses through epitope masking, and 5) inhibition of B cell responses by binding of IgG to the FcγRIIB (134, 135).
Flow cytometry is an evolving field with a wide range of applications that
includes immunophenotyping, cell division and apoptosis, cell activation, intracellular pH shifts,
phagocytosis, oxidative burst and much more.