Sentences with phrase «including rna»

Finally, with a few very notable exceptions, all cells contain a nucleus, and inside of the nucleus are genetic materials including RNA and DNA that both contain phosphorus in their chemical structure.

In addition to the cell walls, other biological molecules are also susceptible to damage, including RNA, DNA and protein enzymes.

Develops novel genomic technologies and computational algorithms to study molecular mechanisms of RNA biology, including RNA modifications, RNA - protein interactions and messenger RNA (mRNA) processing.

This applies to the design and manufacture of RNA, DNA, and viral products for research and laboratory use, including RNA interference, gene expression, and gene editing.

Several applications, including RNA - seq, haplotype sequencing and 16S sequencing, are however limited by its relatively high single read error rate (> 10 %).

The projects will provide training in: current molecular biology techniques (including RNA interference, genetic transformation, analyses of gene expression); cell biology techniques (cell culturing, cell transfections, imaging); protein biochemistry (2D electrophoresis, protein functional analyses); and bioinformatics (structure predictions, phylogenetic analyses; molecular interactions).

The Facility also supports transcriptomic projects including RNA - seq, ChIP - Seq, methylation (MeDIP), small RNA - seq and targeted sequencing.

The team is taking several approaches to inhibit HIF - 1 activity, including RNA interference, dominant negative constructs, and small molecule inhibitors.

Using an array of techniques, including RNA sequencing and targeted gene expression profiling, the researchers searched for links between gene activity and protein production in these tumors and the clinical outcomes of patients.

About 3 — 8 % of human milk fat globules contain mammary epithelial cell cytoplasmic remnants, including RNA, captured during milk fat globule formation and secretion [9].

As the name suggests, ecRNA partially overlaps with a gene sequence that produces messenger RNA; but it also includes RNA sequences from DNA beyond the gene boundary.

The atlas now also includes RNA transcript data for 27 of these organ - specific tissues using next generation sequencing, providing a tissue distribution map of both protein and gene expression.

Proteins are synthesized from instructions coded in the DNA through a multi-step process that includes RNA splicing.

This study was the first to include RNA sequencing in an analysis of HGGs.

Proteins found in stress granules include RNA - binding proteins like TDP - 43, FUS, hnRNPA1 and hnRNPA2B1 that regulate gene activity.

By expanding high - throughput deep phenotyping of cells beyond protein epitopes to include RNA expression, PLAYR opens a new avenue for the characterization of cellular metabolism.

Not exact matches

[242] The beginning of life may have included self - replicating molecules such as RNA [243] and the assembly of simple cells.

The five nucleotides — adenine, thymine, cytosine, guanine and uracil — arranged into DNA and / or RNA The twenty amino acids — that form all proteins, including enzymes and the other 100,000 or so proteins in a complex organism's body.

We have seen quite complex organic chemicals, including all five nucleotides required for DNA and messenger RNA formation (A, G, C, T and U) form spontaneously in «the lab» in conditions that mimic the conditions on Earth during the late Hadean Period (about 3.5 M years ago).

This nutrient is also crucial for «development of new cells, including DNA and RNA,» notes Laura Cipullo, a registered dietitian and creator of Whole Nutrition Services.

The team confirmed that genetic «knockdown» of PRMT1 significantly impaired PDAC cell growth in vitro through use of genetic editing tools, including CRISPR and small hairpin RNA (shRNA).

He arrived in 2012 and now oversees a team of eight scientists (including two Ph.D. s and one M.D.) who support researchers with resources and tools related to RNA interference (RNAi) and CRISPR gene - editing technologies.

Because this imprinting affects hundreds of genes that are non-coding, including microRNAs and non-coding RNAs, it's a very interesting fine - tuning mechanism for the dosage of gene expression in the brain and elsewhere in the body.»

Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interrelationship of DNA, RNA and protein synthesis and learning how these interactions are regulated.

Others include modification of the histone proteins that DNA winds around to form chromatin — the tightly packed cluster that makes up chromosomes — and the activation of small non-coding RNA molecules.

In his second semester, he started doing research in three different labs, including that of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction of messenger RNA.

In aqueous solution, 1 binds readily to a variety of biomolecules, including nucleotides, RNA, amino acids, peptides, and phospholipids.

The protein assembly line consists of microtubules that serve as train tracks on which the raw materials — including messenger RNA (mRNA)-- are carried to the protein - making machinery, called ribosomes.

Using RNA sequencing, the researchers found multiple genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a normal placenta.

Further analysis including in tissues from more patients with other forms of epilepsy also showed that CLOCK RNA and protein were often significantly lacking in both in excitatory and inhibitory neurons in affected brain regions.

These RNA - binding proteins include sequences of amino acids that bind to one of the ribonucleotide bases or «letters» that make up RNA sequences — adenine (A), thymine (T), uracil (U), and guanine (G).

Several species, including Arabidopsis, rice, mice and humans, copy a surprising amount of RNA from the «wrong» DNA strand — that is, the strand opposite the one that specifies a protein.

• During early and late states of infection, Zika RNA was detected in tissues, including the brain and male and female reproductive tissues.

The demonstration of this poison pill in the coxsackievirus B3 could theoretically translate to other positive - sense RNA viruses, including those linked to asthma and to foot - and - mouth disease that is a major animal health concern in Europe and South America.

Once inside, they can disrupt several cellular targets, including DNA, RNA, and proteins.

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

Peersen's group seeks to understand the complex biochemical replication machinery of positive - sense single - stranded RNA viruses, a group that includes coxsackievirus, poliovirus, dengue and Zika.

They found antibodies and viral RNA fragments in three species of bats, including hammer - headed fruit bats.

In cells, U1 snRNP plays multiple roles in processing RNA including the process of alternative splicing, by which one gene can make instructions for two or more proteins.

The newly discovered viruses appeared in every family or genus of RNA virus associated with vertebrate infection, including those containing human pathogens such as influenza virus.

The remaining 90 or so characterized proteins include molecular chaperones, which prevent other proteins from sticking together; translation machinery, which coaxes messenger RNAs and ribosomes to form proteins; and proteins that control the structure of RNA.

This set includes various ribosome builders, as well as other proteins that process and transcribe ribosomal RNA, a necessary step before the ribosomes can be assembled and pushed out of the nucleolus.

Nineteen of the species, including a squirrel, a small bat, a zebrafish, and a human had RNA viral sequences embedded in their DNA.

She has described the impact that different estrogen receptors have on breast, pancreatic, and colorectal cancer, including transcriptomic effects involving long noncoding RNAs and microRNAs.

C. elegans is a microscopic worm that like humans highly expresses a family of proteins in the nervous system called ADARs — adenosine deaminases that act on RNA — a family that includes ADR - 1.

Finally, a Calgary, Alberta — based company, Oncolytics Biotech, is testing a reovirus (an RNA virus often found in human lungs but thought to be nonpathogenic) against several types of cancer, including that of the lung and skin as well as head and neck malignancies.

Many researchers who once focused on messenger RNA and other relatively large RNA molecules have in the past 5 years turned their attention to these smaller cousins, including microRNA and small nuclear RNA.

«RNA interference is activated in human response to influenza, other important viruses: Discovery could lead to better ways of combating serious infections, including Ebola and Zika.»

These biochemical processes are responsible for a broad range of movement in living organisms, including moving molecules around the interior of a cell or copying DNA into another form of genetic material, RNA.

Notably, the phosphorylated proteins included a group called splicing factors, which splice together different sections of messenger RNA, changing the proteins that they encode.