Specifically, the data reveal distinct transitions in factors that influence the different cellular states
including cell cycle regulators, transcription factors, and signaling factors.
Not exact matches
Igoshin said that when the researchers set out to find how sporulation decisions were timed to the
cell cycle, several studies
including prior work by team members, provided a significant clue: Under starvation conditions, the activity of the master
regulator gene had been shown to spike once per
cell cycle.
Its major target genes
include proapoptotic genes Bax, Puma and Noxa,
cell cycle regulator p21, and the senescence - inducing gene Plasminogen activator inhibitor 1 [5].
All CM members have research interests in basic cancer mechanisms,
including the normal functions of oncogenes and tumor suppressor genes;
regulators of
cell cycle and apoptosis;
regulators of angiogenesis and metastasis; and stem
cells and blood formation.