Not exact matches
The scientists,
including Florian Reisinger from the Institute of Virology (HMGU) and Dr. Kristian Unger from the Research Unit Radiation
Cytogenetics (HMGU) showed this using mouse models.
Dr. Schwartz's main research interests
include molecular
cytogenetics, particularly understanding the causes and effects of chromosomal abnormalities.
The primary goal of this facility is to offer conventional and molecular
cytogenetic services,
including species identification, karyotyping, analysis of genomic instability, fluorescence in situ hybridization and spectral karyotyping
A large variety of methods is used
including genetic, molecular and
cytogenetic techniques, fluorescence in situ hybridisation and DNA «combing», as well as high throughput sequencing approaches such as DNA - seq for mutation landscape analyses, RNA - seq for transcriptome analyses and ChIP - seq mapping of chromatin - associated proteins and their genome - wide modulation in response to DNA damages.
Our major resource development projects involve both data and biological resources for a variety of programs
including the Mutant Mouse Resource and Research Center at JAX, the Special Mouse Strain Resource, the Mouse Mutant Resource and NICHD's
Cytogenetic Models Resource.
This approach is now being used to derive embryonic stem cells from a variety of strains
including disease models from which in vitro tools are in demand,
including mouse models of Alzheimer's disease,
cytogenetic disorders (Turner's syndrome and Down syndrome), and tool strains for systems genetics.
Topics explored by AJHG
include behavioral genetics, biochemical genetics, clinical genetics,
cytogenetics, dysmorphology, gene therapy, genetic counseling, genetic epidemiology, genomics, immunogenetics, molecular genetics, neurogenetics, and population genetics.
An overall theme of the Morton Laboratory is to apply evolving techniques in molecular
cytogenetics to address problems in human
cytogenetics, with interests
including chromosomal rearrangements in constitutional and acquired
cytogenetic disorders.
Comparative
cytogenetic data on Cricetinae suggest that their evolutionary history
includes both periods of chromosomal conservatism and episodes of rapid chromosomal change.
He has been most involved in the defense of labs in Pap smear (cytology) and
cytogenetics litigations,
including litigating these matters as national counsel to the largest clinical laboratory in the country, in the state and federal courts of numerous states,
including New York, New Jersey, Ohio, Illinois, Missouri, Texas, California, and Arizona.
Mr. Sidoti has represented the entire range of laboratory and other healthcare professionals and para-professionals,
including pathologists, cytotechnologists, and lab technicians, on behalf of major clinical laboratories and smaller entities, in matters involving the disciplines of cytology, pathology, and
cytogenetics, as well as general laboratory testing in the areas of chemistry, hematology, and toxicology.