Sentences with phrase «including embryonic development»

According to the researchers, these findings suggest that differences in shape from cell - to - cell within a tissue are key to their ability to jam and unjam — and that this process appears to drive biological events including embryonic development, wound healing, and, potentially, cancer cell invasion.

Not exact matches

A working knowledge of pregnancy and human development from the anatomy and physiology point of view including fertilization, basic embryonic development, and basic fetal development.

«Furthermore, results of our study highlight the importance of including moisture conditions when predicting embryo growth and sex ratios and in developing proxies of embryonic development.

These include a family of signaling molecules called protocaderins, which regulate neuronal development and short - range interactions between neurons, and a family of transcription factors called zinc fingers, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in brain development.

It performs this critical service in embryonic development, growing organisms and in a few specialized adult cell lines, including stem cells.

Neurocutaneous disorders are caused by abnormal development of cells in the embryonic stage, leading to tumors in various parts of the body, including the skin, organs, bones, brain and spinal cord.

Rivolta and his colleagues knew that during embryonic development, a handful of proteins, including fibroblast growth factor (FGF) 3 and 10, are required for ears to form.

To find out what these genes do, and which ones are master regulators of development, researchers have several approaches, including deactivating embryonic genes in mice.

Other potential uses of embryonic stem cells include investigation of early human development, study of genetic disease and as in vitro systems for toxicology testing.

Cook's illustrious subjects include the umbrella - bearing British cosmologist Sir Martin Rees of the University of Cambridge, the wrinkle - faced late naturalist and flea expert Miriam Rothschild, and the biologist Christiane Nüsslein - Volhard (left) of the Max Planck Institute for Developmental Biology in Tübingen, Germany, who won the 1995 Nobel Prize in Physiology or Medicine for codiscovering key genes that shape embryonic development.

My research interests include investigating the role of RNA degradation in Drosophila development, investigating the impact of wounding in the Drosophila embryonic central nervous system, and investigating the effect of protein degradation on the activity of different transcription factors in neuronal fate decisions during nervous system development in Drosophila.

The challenge takes on even more urgency with recent developments, including a federal administration now more open to exploring the potential of stem cells, the recent FDA approval of a human trial involving embryonic stem cells, as well as the reported case of a young boy who developed a brain tumor four years after receiving a stem - cell treatment for a rare genetic disorder.

Moreover, ES cell differentiation in vitro recapitulates events that take place during early embryonic development including the formation of the three germ layers of ectoderm, mesoderm and endoderm, and the emergence of endothelial, hematopoietic, cardiac, neuronal and hepatic or pancreatic cells [8], [9].

For example, clusters containing genes that are upregulated during the course of ES cell differentiation (Table 3) include in order of time of expression: cluster 30 that represents genes which take part in the formation of the three embryonic germ layers during gastrulation, i.e., Goosecoid, Cerberus like 1 homolog, Wnt3, Mesp1, Mixl1, mEomes and Even - skipped 1; cluster 15 containing molecular regulators of early mesoderm development including Bmp2, Bmp5, Msx1, Msx2, Cripto, Tbx20, Hey2, Smad6, Vegfr2 (Kdr), Foxf1 and Hand1; cluster 20, which comprises regulatory and structural genes linked to hemopoiesis such as Gata1, Nfe2, Klf1, Tie1, hemoglobins (Hba - x, Hbb - b1) and Glycophorin A; cluster 12, which is rich in genes involved in cardiac development, e.g., Mef2c, Myl4, cardiac Troponin T2, Tropomodulin 1, myosin binding protein C, Bves, Angiopoietin 1 and Angiopoietin 2; and, cluster 4, which consists mostly of genes associated with neuronal development and differentiation, for example, Neurog1, Neurog2, Olig2, Nkx6.1, Neurod4, Pou3f2, Pou3f4, Cacna2d3, Cacng4, Kcnq2 and EphA5.

Other gene families that were dramatically expanded in the octopus include zinc finger transcription factors, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in development.