The researchers» next step is to use the genomic data they collected from the families —
including full genome sequences and gene expression data — to begin identifying the specific genes that contribute to risk for bipolar disorder.
Not exact matches
Most animals,
including humans, have two copies of their
genome — the
full set of instructions needed to make every cell, tissue, and organ in the body.
On 20 December 2013, a paper by the Amborella
Genome Sequencing Project that
includes a
full description of the analyses performed by the project, as well as implications for flowering plant research, will be published in the journal Science.
Possible biological explanations for the findings
include changes in the immune tolerance of the embryo, whose
full genome is not concordant with the recipient's.
The research team, which also
included scientists from the University of Utah and Stockholm's Karolinska Institute, developed in vitro models of HIV — 1 latency in T cells that harbor a
full - length HIV
genome.
Y - chromosome haplotypes were recovered by aligning reads against previously identified Y - chromosome contigs (12, 75), first against the contigs alone and then remapped against the
full nuclear
genome,
including the Y - chromosome contigs, to control for repetitive regions.
In both cases, the results are based on the same set of blastp searches, in which we blasted each Nasonia gene against the predicted proteomes of 30 additional species,
including 12 additional Hymenoptera
genomes, 6 Dipteran
genomes, 5 additional insect
genomes, 2 additional non-insect arthopod
genomes, and 5 non-arthropod outgroup
genomes (see Table S4 for the
full list,
including gene model versions and data sources).
Data delivered
includes the
full data set for each
genome within the Sample Group as well as results from paired analysis between the tumor and the matched normal
genome samples.
The publication of the P. falciparum
genome project in 2002 [10] identified the
full complement of parasite proteins but progress in understanding the function of these proteins,
including those displayed on the merozoite cell surface, has been hindered by the technical difficulties in expressing Plasmodium proteins in a functionally active form [11].
The classic data of bioinformatics
include DNA sequences of genes or
full genomes; amino acid sequences of proteins; and three - dimensional structures of proteins, nucleic acids and protein — nucleic acid complexes.