Sentences with phrase «including gene deletion»

Such methods include cell fusion, microencapsulation and macroencapsulation, and recombinant DNA technology (including gene deletion, gene doubling, introducing a foreign gene, and changing the positions of genes when achieved by recombinant DNA technology).»

Not exact matches

My background has included: PCR, gene synthesis, cloning, codon optimization, site - directed mutagenesis, chromosomal gene integration / deletion, albumin fusion, fermentation using NBS BioFlo3000, SDS - PAGE, Coomassie staining, and Western blotting.

In this study, the researchers found that conditional deletion of Sox2 — the gene encoding the SOX2 stem cell transcription factor — and the associated dampening of astrocyte reactivity appear to promote functional recovery, including behavioral recovery, after traumatic brain injury, said Dr. Zhang, a W.W. Caruth, Jr..

A very rare form of a thalassemia is due to a deletion of a larger area of chromosome 16 including the a globin genes.

Future posts will include non-homologous end joining, using CRISPR for gene activation, creating deletions using CRISPR - Cas tools, validation, and more.

«In 100 percent of small - cell lung cancers, there is a deletion in this region of chromosome 3, very often including the HYAL2 gene,» he said.

Forms of variation include single DNA base pair alterations, duplications or deletions of genes or sets of genes, and translocations, a chromosomal rearrangement in which a segment of genetic material from one chromosome becomes heritably linked to another chromosome.

Using our own data and publically available data from array comparative genomic hybridization (aCGH), we identified a minimal deletion for the cardiomyopathy associated with del1p36 that included only the terminal 14 exons of the transcription factor PRDM16 (PR domain containing 16), a gene that had previously been shown to direct brown fat determination and differentiation.

For each mouse line, Lexicon provided not only the mouse strain itself, but also detailed, objective data on the impact of the specific gene deletion on the mouse's phenotype, which includes appearance, health, fitness, behavior, ability to reproduce, and radiological and microscopic data.

Known and novel independent prognostic markers were identified in our cohort of proteasome inhibitor and IMiD - treated patients with long follow - up, including events with context - specific prognostic value, such as deletions of the PRDM1 gene.

For each mouse line, Deltagen provided the mouse strain, but also detailed, objective data on the impact of the specific gene deletion on the mouse's phenotype, which includes appearance, health, fitness, behavior, ability to reproduce, and radiological and microscopic data.

They also described the gene's size and genetic deletions associated with disease, including a very large deletion of the gene coding for dystrophin found in a patient with mild disease.

CEA, which segregates in several herding breeds with Collie ancestry, was mapped to a large region of CFA37 that included over 40 genes [92]; subsequently the fact that the disorder segregates in multiple, closely related breeds was used to reduce the size of the critical disease - associated region and pinpoint the causal mutation to a 7.8 kb intronic deletion in the NHEJ1 gene, which spans a highly conserved binding domain to which several developmentally important genes bind [91].