Sentences with phrase «including genes encoding proteins»

This finding is consistent with the recent discovery with several «eukaryotic» signature genes in these archaeal lineages, including genes encoding proteins such as actin, tubulin, and several proteins involved in transcription and membrane deformation.

Not exact matches

The study results build on genetic and epigenetic basics, including that the blueprint for the human body is encoded in genes that direct the building of one or more proteins.

Genes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protGenes may carry information for building proteins, but a host of other factors, including the DNA between genes that doesn't encode proteins, tells them when to make their protgenes that doesn't encode proteins, tells them when to make their proteins.

The MECP2 gene encodes methyl - CpG - binding protein - 2 (MeCP2), a transcriptional regulator of many genes including brain - derived neurotrophic factor (BDNF).

And many genes encode proteins for molecular pumps that spit out foreign molecules — possibly including antibiotics — to detoxify the bacteria.

The newly identified mutation affects a gene called APP, which encodes a protein that gets broken down into pieces, including β amyloid.

This includes how subtle changes in gene sequences can impact the expression of encoded proteins through mechanisms including codon bias, mRNA stability, and translation initiation.

Quantitative analyses of multiple cardiac phenotypes demonstrated essential structural, functional and developmental roles for these genes, including a subgroup encoding histone H3K4 modifying proteins.

Functional perilipins (PLIN proteins encoded by the PLIN genes)(Lu et al., 2001) have been identified in very diverse organisms such as Drosophila (Teixeira et al., 2003), Dictyostelium (Du et al., 2013) and fungi (Wang & St Leger, 2007) and protein databases list clear orthologues in diverse, non-plant eukaryota, including the simplest metazoan Trichoplax adherens, sponges, crustaceans, and choanoflagelates (UniProt proteins B3RRM2, I1GA14, G5DCP6, F2UJD9, respectively).

Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.

The TOMM40 gene encodes a barrel - shaped protein in the outer membrane of mitochondria that forms a channel for molecules — including the precursor to amyloid — to enter.

Upregulated genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.

Previous studies have implicated FOXM1, which encodes a transcription factor protein capable of regulating the activity of many other genes, in many other human cancers, including liver, breast, lung, prostate, colon, and pancreatic cancers.

This type of «killer» T cell responds to previously encountered cell - surface molecules — including the fragments of SIV proteins encoded by the genes in the CMV / SIV vaccine — and destroys SIV - infected cells.

Based on these sources, we identify 497 genes with possible immune function in Nasonia (Table S1), including 75 encoding effectors (AMPs, proteins in the prophenoloxidase cascade, transferrins, and peroxidases), 96 encoding recognition proteins (including PGRPs, TEPs, Nimrod - like proteins, and numerous lectins), 101 encoding signaling proteins, and 225 encoding proteases or protease inhibitors.

A protein called disrupted - in - schizophrenia 1, encoded by the DISC1 gene, has been established as a genetic risk factor for a wide array of psychiatric disorders, including schizophrenia, bipolar disorder, major depression,...

B) Short genes, which includes only genes encoding proteins between 134 and 456 amino acids, inclusive.

The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that control cells and circumstances in which a gene is active.

The new gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version.

Additional upregulated signal transduction related genes encoded proteins polycystin - 1L1, MLP and LIM regulatory proteins, fibrillins or related proteins containing Ca2 + - binding EGF - like domains, Ca2 + / Mg2 + - permeable cation channel, and other differentially expressed putative transcripts that may play a role in cellular signaling, including known extracellular proteins c - type lectin and collagen (see electronic supplementary material, table S5).