Researchers from the University of Cambridge studied a variety of cell lines,
including human neural stem cells, to investigate how Zika virus infection can lead to microcephaly.
Not exact matches
Within two to 12 weeks, the organoids were sprouting additional neurons,
including ones found in very specific regions of the
human cortex; glia
cells including astrocytes; and
neural stem cells.
The approach enabled a wide range of studies of
human brain development,
including implicating a new class of
neural stem cell recently discovered by the lab in the evolutionary expansion of the
human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.
Human embryonic
stem cells can turn into a variety of different
cell types,
including (A) gut, (B)
neural cells, (C) bone marrow
cells, (D) cartilage, (E) muscle, and (F) kidney
cells.
On the other hand, ES
cells and
cells differentiating into endoderm and mesoderm lineages from ES
cells express OCT - 4 in mice and
humans [66], and SSEA1 expression is found in other type of
cells including neural stem cells and mesenchymal
stem cells [67], [68].