Sentences with phrase «including immunomodulatory»
Multiple classes of agent with distinct mechanisms of action are now available for the treatment of patients with relapsed and / or refractory multiple myeloma (RRMM), including immunomodulatory agents, proteasome inhibitors, histone deacetylase inhibitors and monoclonal antibodies.
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These include pro-inflammatory T helper cells, or Th1, that produce interferon - γ and interleukin - 2, or IL - 2; anti-inflammatory Th2 cells that produce IL - 4, IL - 5 and IL - 13; pro-inflammatory Th17 cells that secrete IL - 17; and immunomodulatory regulatory T - cells, or Tregs, that globally suppress activation of immune responses.
Development of systems comprising detoxified LPS immunomodulatory adjuvants (ITV): Detoxified LPS immunomodulatory adjuvants are the most common PAMP compounds, but only one variant (from Salmonella) is currently included in a registered adjuvant product.
Detoxified LPS immunomodulatory adjuvants are the most common PAMP compounds, but only one variant (from Salmonella) is currently included in a registered adjuvant product.
The final aim is improving therapeutic effect and defining rationalized drug combinations with immune checkpoints and proprietary molecules developed by collaborators, including novel immunomodulatory approaches generated at our unit.
Cancer stem cells (CSCs) in the hypoxic BM regions are blamed for the incurability of MM, because CSCs are often resistant to drugs currently used against BM cancers (including proteasome inhibitors and immunomodulatory agents).
A rapidly growing number of published studies have shown that M. oleifera leaves possess a wide range of additional biological activities including antioxidant, tissue protective (liver, kidneys, heart, testes, and lungs), analgesic (pain relieving), antiulcer, antihypertensive, radioprotective, and immunomodulatory actions.
There are also some other medications that we can add in, including certain antihistamines and a prescription medication called Atopica, which is cyclosporine, an immunomodulatory drug that also helps cats with these hypersensitivity reactions.»