Sentences with phrase «including microarray»

Prior to working at City of Hope, she worked as a research associate in Dr. Peter Lee's lab at Stanford University since 2006 and facilitated in investigating mechanisms causing immune dysfunction in melanoma and breast cancer patients» peripheral blood, lymph node and tumor specimens utilizing techniques including microarray analysis, RT - PCR, Phospho - flow cytometry, histoloogy, and functional FACS studies.

Results: Benefiting from the recently sequenced genome of the model sulfate - reducing bacterium (SRB), Desulfovibrio vulgaris, microbiologist Weiwen Zhang and a team of scientists at Pacific Northwest National Laboratory (PNNL) are applying a suite of post-genomics technologies, including microarray, proteomic, and computational analyses, to obtain a broader understanding of D. vulgaris» metabolism.

Therefore, before publication, large data sets (including microarray data, protein or DNA sequences, atomic coordinates or electron microscopy maps for molecular and macromolecular structures, and climate data) must be deposited in an approved database and an accession number or a specific access address must be included in the published paper.

Services provided by EMBL Heidelberg include the Core Facilities which provide internal users, collaborators and visitors with access to excellent facilities for high - throughput analysis including microarrays, protein production, mass spectrometry, DNA sequencing, advanced light and electron microscopes and chemical genomics.

Not exact matches

This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.

The Emory team used high density microarrays to probe more than 900,000 sites across the human genome to detect structural variation, including deletions or duplications of DNA.

Guidelines exist for the appropriate design and conduct of studies in some fields, including animal research and microarray experiments.

A total of 24 mice were included in the microarray expression study, four from each of the following groups: C57BL / 6J males, C57BL / 6J females, high fat — fed C57BL / 6J males, B6.Cg Ay / + females, B6.V Lepob / ob males, and B6.V Lepob / ob females.

The Monash BDI researchers worked in collaboration with Canadian - based company Kinexus, and used an antibody microarray to simultaneously investigate hundreds of factors involved in cell signalling that were modulated by HCV replication, including human protein kinases.

We offer a wide range of services, including capillary sequencing and genotyping, Illumina microarray - based gene expression profiling and genotyping, and next - generation sequencing (NGS).

We are now expanding this facility to not only include state - of - the - art protein domain microarrays, but also to allow the further characterization of these protein - protein interactions in cells.

The Research Histology Core Laboratory includes specialized equipment for immunohistochemistry, fluorescent in situ hybridization FISH, laser capture microdissection, and tissue microarray construction.

Bioinformatics services include data QC, outlier detection and general data management, and data analysis from platforms including Illumina or Affymetrix microarrays, RNA - Seq, SNP arrays, Exome - sequencing, ChIP - chips and CHIP - seq.

Therefore, we used microarray analysis to perform pairwise comparisons of the transcriptional profile of EFTF - expressing pluripotent cells to three regions of the Xenopus embryo: the eye field (EF) including underlying mesendoderm, posterior neural plate (PNP) and the non-neural, flank, lateral endoderm (LE, Figure 1A).

The department has expertise and infrastructure to support bacterial and viral analysis, and the detailed evaluation of cellular and serological immune responses including flow cytometry and cell sorting, Luminex multiplex platforms, real time PCR, microarrays, comprehensive histological staining, immunohistochemistry and in - situ hybridisation.

Total RNA was labeled and hybridized against custom S. pistillata microarray; an Agilent two - color gene expression microarray platform with 8 × 15 K probe per slide; microarray samples included four SW +100 and four SW (control) samples for each time point (11:00 and 23:00).

We apply FARO to a compendium of 242 diverse Arabidopsis microarray experimental factors, including phyto - hormones, stresses and pathogens, growth conditions / stages, tissue types and mutants.

The tissue microarray method used within the human protein atlas enabled the global mapping of proteins in the human body, including the brain.

Research on vaccine biomarkers, including in - depth comparative analysis of data from different platforms, large - scale RNA sequencing, harmonisation of standard operating procedures (SOPs) for sample, microarray and data analysis, as well as transcriptome mapping (more than 1400 samples analysed).

The students are employing that technology — which includes CRISPR (clustered regularly interspaced short palindromic repeats) systems, DNA microarrays, real - time polymerase chain reactions, RNA sequencing and western blotting — to study acute myeloid leukemia (AML), which affects both children and adults and comes with a high mortality rate for older patients.

Similarly, microarray analyses comparing global gene expression in cells that overexpress wild - type STAT3 or phosphorylation - deficient mutant indicate that a subset of genes are regulated by unphosphorylated STAT3, including well - known oncogenes such as MRAS and MET (Yang et al., 2005).

Services include phlebotomy, tissue microarrays, collection of pathological specimens and support for clinical studies.

The current study included 3,215 RS participants who had both SNP microarray data and 3D MRI.

His contributions include the first use of genetic methods to identify an infectious agent; implication of West Nile virus as the cause of the encephalitis in North America in 1999; invention of MassTag PCR and the first panmicrobial microarray; first use of deep sequencing in pathogen discovery; and molecular characterization of more than 600 viruses.

This is in contrast to known genes where 21 % have a particular pattern, possibly because a number of ESTs included in the microarrays are cloning artifacts.

Specifically, we have generated clusters of transcripts that behave the same way under the entire spectrum of the sixty - seven experimental conditions; we have assembled genes in groups according to their time of expression during successive days of ES cell differentiation; we have included expression profiles of specific gene classes such as transcription regulatory factors and Expressed Sequence Tags; transcripts have been arranged in «Expression Waves» and juxtaposed to genes with opposite or complementary expression patterns; we have designed search engines to display the expression profile of any transcript during ES cell differentiation; gene expression data have been organized in animated graphs of KEGG signaling and metabolic pathways; and finally, we have incorporated advanced functional annotations for individual genes or gene clusters of interest and links to microarray and genomic resources.

In contrast to existing microarray database resources, the FunGenES database includes a state of the art tools for the interactive visualization of gene to gene relationships.

His product experiences include clinical chemistry, special chemistry, histology, immunohistochemistry, electrophoresis, immunoassay, HPLC, microarray, MA and DNA separation and purification.

• Organized workflow directed towards bioassay design using Protein and DNA signatures on microarrays to test efficacy of detecting bio-threats from samples that included challenged and naturally occurring outbreaks.

It includes developmental genetics, dysmorphology, genetic counseling, prenatal diagnosis, molecular diagnostics, microarray techniques in practice, community genetics and more..