Sentences with phrase «including noncoding»

Not exact matches

She has described the impact that different estrogen receptors have on breast, pancreatic, and colorectal cancer, including transcriptomic effects involving long noncoding RNAs and microRNAs.

Noncoding DNA includes stretches called enhancers, short sequences that help control a target gene.

That DNA includes slightly less than 21,000 protein - coding genes (some researchers once estimated we had more than 100,000 such genes); «genes» for 8800 small RNA molecules and 9600 long noncoding RNA molecules, each of which is at least 200 bases long; and 11,224 stretches of DNA that are classified as pseudogenes, «dead» genes now known to really be active in some cell types or individuals.

Clariom D Pico assays allow discovery of coding and noncoding genes, exons, and splicing events, including rare transcripts, expanding the potential for finding novel biomarkers missed by alternative techniques.

Using a specific work flow, they assessed both the coding and noncoding regions of the human genome, including the evaluation of highly polymorphic SNPs, structural and copy number variations, as well as 69 control genomes sequenced by the same procedures.

In the June update, 278 retinal disease genes had been mapped, including first bona - fide noncoding gene linked to a retinal disease.

Studies of the host response to viral infection have historically focused on protein - coding genes, thus our understanding of how the non-protein-coding transcriptome, including both viral - and host - derived noncoding RNAs, impacts host - virus interactions is limited.

These included tier 1 (coding), tier 2 (conserved / regulatory), and tier 3 (unique noncoding) variants.

Sessions will cover recent findings in RNA polymerase II regulation, including the contributions of noncoding RNAs, chromatin structure and post-translational modifications, and other factors that regulate gene expression.

In it, the authors review bioinformatics approaches for evaluating single - base substitutions in both coding and noncoding regions, with an emphasis on large cancer resequencing efforts including the Tumor Sequencing Project, the Cancer Genome Atlas (TCGA), and the AML1 cancer genome.

Throughout the 2000s, Wistar scientists made seminal discoveries in the field of epigenetics and RNA transcription, contributing new knowledge on the role of histone modifications in gene regulation and DNA repair and how different RNA species, including microRNAs (miRNA) and long noncoding RNAs (lncRNA), are generated and how they regulate gene transcription.