Sentences with phrase «including pembrolizumab»

Not exact matches

We are currently waiting for the results of several trials including EORTC 1325 which is investigating pembrolizumab, a PD - 1 checkpoint blocking antibody, compared to placebo in the adjuvant setting.»

«The reason KEYNOTE - 024 met its primary endpoint, in contrast with other studies, is probably because the trial only included patients who had PD - L1 expression of at least 50 % and were therefore optimal candidates for treatment with pembrolizumab,» he added.

The trial included 305 patients from 16 countries who were randomised 1:1 to pembrolizumab or chemotherapy.

Alley and his team presented data from KEYNOTE - 028, an ongoing trial involving 13 different research sites in six different countries all looking at the effect of pembrolizumab on patients with advanced malignancies, including malignant pleural mesothelioma.

Checkpoint inhibitors such as ipilimumab, nivolumab and pembrolizumab have had a dramatic impact on treatment of several tumor types, including melanoma, lung cancer, head and neck cancers and others.

Aside from atezolizumab, immunotherapies in this class include avelumab (Bavencio); pembrolizumab (Keytruda); and nivolumab (Opdivo).

Zakharia, who presented the data at the 2017 American Association for Cancer Research (AACR) Annual Meeting in Washington, DC, reveals the overall response data from the trial, toxicity data, and compares the results to historical data of pembrolizumab monotherapy from KEYNOTE - 006, which included similar patients.

Because they stimulate the immune system rather than introducing an agent or process that can kill healthy cells along with the malignant ones, these therapies — which include commonly prescribed treatments such as trastuzumab (Herceptin), pembrolizumab (Keytruda) and nivolumab (Opdivo)-- have been noteworthy not only for their effectiveness but for their tolerability.

The study will include 330 patients receiving T - VEC plus pembrolizumab and 330 patients taking placebo injections plus pembrolizumab.

Paris Descartes APHP and INSERM Poster # / Location: 4546 / Section 25, Board 1 Hyperlink: http://www.abstractsonline.com/pp8/#!/4562/presentation/7648 The tumor inflammation signature (TIS) and other gene expression signatures, simultaneously analyzed using the IO 360 panel, predict clinical benefit of anti-PD1 treatment (nivolumab and pembrolizumab) in «real life» patients with various cancer types, including NSCLC.