Sentences with phrase «increase cholesterol synthesis»

MicroRNAs that reduce cholesterol export from cells are encoded in the same genes that increase cholesterol synthesis.

Coconut really throws the whole «marker» issue out of whack because it increases the energy state of the cell, which increases cholesterol synthesis.»

Not exact matches

Their work laid the groundwork for drugs called statins that block cholesterol synthesis, increase LDL receptors, lower blood cholesterol and prevent heart attacks.

Despite this possibility, mevinolin, the active ingredient in red yeast rice, is capable of reducing 7 - dehydrocholesterol levels, 22 and simvistatin (Zocor) not only inhibits the synthesis of mevalonate but also enhances the conversion of 7 - dehydrocholesterol to cholesterol by increasing the expression of 7 - DHCR.23 Simvistatin thereby hits the pool of 7 - dehydrocholesterol with a double - whammy, both decreasing its synthesis and increasing its degradation.

Increased enterohepatic circulation on high fat means that cholesterol is kept «in play» - bounced back into the bloodstream in ApoB particles - while low enterohepatic circulation, in people with with higher synthesis rates, during weight loss - when cholesterol is being dumped by shrinking cells - means that cholesterol can pile up in the gall bladder faster than it can be conjugated to bile salts and bile acids and faster than it can be extracted by the weak stimulus of low fat food.

The second group will, I think, tend to see LDL drop if fasting because intracellular cholesterol synthesis will drop faster than cholesterol (re) absorption will increase.

Needless to say the second group was hyperinsulinaemic and IR; insulin stimulates cholesterol synthesis and inhibits (re) absorption, while glucagon has the opposite effect; enterohepatic bile cycling is increased by glucagon.

For example the most powerful increaser of total cholesterol is probably lauric acid, but lauric acid is also the most powerful reducer of the LDL - to - HDL - cholesterol ratio — this is consistent with lauric acid being burned for quick energy, thus increasing the energy state of the liver cell and allowing for greater cholesterol synthesis.

[2] No surprises then that cholesterol synthesis is found to be increased in type 2 diabetes.

A key enzyme in cholesterol biosynthesis is 3 - hydroxy -3-methylglutaryl — CoA reductase (the target for statins), which is activated by insulin, which means that an increase in blood glucose and consequently of insulin levels will lead to increased endogenous cholesterol synthesis.