Sentences with phrase «increase efflux»

Not exact matches

Specifically, these investigators showed that the levels of several efflux (P - glycoprotein, MRP1, ABCG1) and influx (SLC15A1) pumps were found to increase by several fold within hours of adjudin treatment (27).

Indeed, we found that long - term drug treatments were associated with increased expression of several ABC efflux transporters and influx transporters.

TZDs increase systemic insulin sensitivity and adipose tissue triglyceride storage while decreasing adipose tissue fatty acid efflux (83).

To check for the presence of this subpopulation of SP cells, we exposed HCT116 to increasing concentrations of Bleomycin and performed Hoechst efflux assay.

A significant population of cells was observed to efflux Hoechst 33342 dye when treated with increasing concentration of Bleomycin (20, 40, 60, 80 μM)(Fig 1a and 1b).

The resulting phenotype is highly motile and possesses stem - cell - like properties, a high degree of resistance to treatments, and an increased rate of drug efflux.

Additionally, cells treated with MIA - 602 showed a significant increases in Calcein dye retention, indicating that efflux pump function was reduced.

In this anabolic effect, HGH can decrease the efflux and increase the influx of amino acids entering the cells.

Increase the influx and the steady state rises but the efflux rate stays the same.

After the hurricane had passed, soil carbon - dioxide efflux — due to microbial and plant respiration — increased while gross primary productivity decreased.