Sentences with phrase «increase in deletions»

Not exact matches

For some reason on Jan 1, 2016 I made a note in the «Additions and Deletions» tab that they didn't increase their 2015 dividend compared to 2014, but this is just wrong.

The company saw some 400,000 account deletions, while rival Lyft saw a 60 percent increase in new users, Lyft head of product Taggart Matthiessen told Recode.

Deletion of the GM - CSF gene in the mouse led to reduction and impaired regulatory function of gut tissue macrophages and dendritic cells which compromised induction of tolerance to food antigens and increased mice susceptibility to IBD.

The children in the study have 22q11.2 deletion syndrome, which is linked to a 25-fold increase in the risk of developing a psychotic condition such as schizophrenia.

A deletion in the region is also associated with an increased risk of autism.

«The IRGM deletion may increase risk of Crohn's by only 40 percent, but it does so in millions of people,» he says.

A new study links a deletion in a neurotransmitter receptor gene to a marked increase in an individual's ability to remember emotionally charged events.

Deletion of DGKζ from T cells results in prolonged TCR signal transduction downstream of DAG, resulting in enhanced activation of Ras, increased effector T cell proliferation, and amplified cytokine production, which leads to increased antitumor activity against s.c. implanted EL4 tumors or murine mesothelioma (12, 16, 17).

Increased T - cell Infiltration Elicited by Erk5 Deletion in a Pten - Deficient Mouse Model of Prostate Carcinogenesis.

In these situations, rather than eliminating the neoplastic clone, deletion of mutant cells can paradoxically lead to their increased turnover.

However, in subgroup analyses stratified by age, we found that the deletion allele was associated with increased risk for lung cancer among individuals < 50 years of age (OR 2.17, CI 1.19 - 3.97), and that the association was gradually reduced with increasing age (p = 0.01).

We also show that PCR conditions and primersets must be carefully chosen to avoid biases in the retrieved variants and an increase in background noise, and established a lower detection limit of 0.5 % heteroplasmic load for large deletions, and 1.5 and 2 % for SNVs, for bulk DNA and single cells, respectively.

We describe heterozygous ACTB deletions and nonsense and frameshift mutations in 33 individuals with developmental delay, apparent intellectual disability, increased frequency of internal organ malformations (including those of the heart and the renal tract), growth retardation, and a recognizable facial gestalt (interrupted wavy eyebrows, dense eyelashes, wide nose, wide mouth, and a prominent chin) that is distinct from characteristics of individuals with BRWS.

In Figure 5 — figure supplement 1, sox32 deletion also seems to increase fn1a staining.

This increase in NAD levels is far superior compared with the 2-fold increases generally observed in most genetic (PARP - 1 deletion), pharmacological (NAD precursors), or physiological interventions (fasting, calorie restriction) that enhance NAD content.

The increase in intracellular NAD elicited by CD38 deletion significantly activated SIRT1 and prompted clinical phenotypes similar to those expected for SIRT1 activation, including protection against diet - induced obesity and a robust deacetylation of SIRT1 targets.

Alternatively, debt settlement with a collection agency may actually increase your score if you are able to negotiate a total deletion from your credit reports in exchange for payment in full.

The company found that app removals increased by 238 percent in October 2016, with mobile games seeing the most deletions.