Sentences with phrase «increase of adverse reactions»

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

Taking antibiotics when they are not needed creates additional health risks as it increases the chance a patient will experience an adverse drug reaction, and also leads to the development of antibiotic - resistant bacteria which affects everyone in the community.

It is hard to understand why governments defend a system with such a poor record, or why they are dismissive of new technologies that promise increased patient safety while decreasing the time and cost of drug development, not to mention the savings to healthcare systems from fewer adverse drug reactions.

The increased risk closely correlates with the frequency of a gene variant previously associated with that adverse reaction, supporting recommendations to screen for that variant in patients from those populations.

The goal of the lab's research is to prevent adverse drug reactions in veterinary patients, which increase patient morbidity and mortality, and add to the overall cost of veterinary care.

As a result, the levels of these drugs may be increased in the blood, and may cause increased effects or potentially serious adverse reactions.

While prostate changes can occur with testosterone replacement, a study published in The Journal of Clinical Endocrinology & Metabolism in June of 2010, which looked closely at the adverse reactions reported in 51 other studies, found there to be no increased risk of the development of prostate cancer, prostate related urinary symptoms, or elevated PSA (prostate specific antigen).

Start with 2 sets of 10 once a day and increase a little every two or three days when you are sure there has been no adverse reaction (pain).

A study published in March 2015 in the Journal of the American College of Cardiology cites clinical data showing that even in the absence of an actual increase in blood pressure, excess sodium in the diet could harm the body, including blood vessels (for example, increased arterial stiffness), the heart (enlarged heart muscle), the kidneys (reduced renal function), and the brain (adverse sympathetic nervous system reactions).

The amount of blood volume needed to be taken from a cat and their small size in combination with using a sedative may increase the risk of an adverse reaction such as low blood pressure.

Despite studies showing that each additional vaccine given during one visit dramatically increases the chance of an adverse reaction, reps peddle products with as many as 7 vaccines to be given at once — with no warnings.

And the rate of adverse reactions decreased significantly as body weight increased.

Removal of sex organs also significantly increases the odds of adverse reactions to vaccines (ref # 4) and inclines both sexes to alopecia, hip dysplasia, and cruciate ligament rupture.

Sterilization confers an increased susceptibility to infectious disease, and also a higher incidence of adverse reactions to vaccines.10 So there is no need to feel obligated to sterilize for health or welfare reasons.

• increases the risk of cardiac hemangiosarcoma by a factor of 1.6 • triples the risk of hypothyroidism • increases the risk of progressive geriatric cognitive impairment • triples the risk of obesity, a common health problem in dogs with many associated health problems • quadruples the small risk (< 0.6 %) of prostate cancer • doubles the small risk (5; this is a common cancer and major cause of death in some breeds • triples the risk of hypothyroidism • increases the risk of obesity by a factor of 1.6 - 2, a common health problem in dogs with many associated health problems • causes urinary «spay incontinence» in 4 - 20 % of female dogs • increases the risk of persistent or recurring urinary tract infections by a factor of 3 - 4 • increases the risk of recessed vulva, vaginal dermatitis, and vaginitis, especially for female dogs spayed before puberty • doubles the small risk (< 1 %) of urinary tract tumors • increases the risk of orthopedic disorders • increases the risk of adverse reactions to vaccinations One thing is clear — much of the spay / neuter information that is available to the public is unbalanced and contains claims that are exaggerated or unsupported by evidence.

Cats metabolize some NSAIDs drugs more slowly than dogs, potentially increasing the risk of adverse drug reactions.

You may have heard recently in the news that there has been an increase of the number of adverse reactions to over-the-counter «spot on» flea and tick treatments.

In older animals, chest radiographs and electrocardiogram (ECG) are often recommended to ensure there is no pre-existing pathology in the heart or lungs that might increase the risk of an adverse reaction.

Because vaccinating an animal which is already immune to a disease does not increase their immunity but does in fact raise the risk of adverse reactions, it is important to avoid over-vaccination.

Therefore, we should advise companion animal breeders and caregivers of the potential for genetically susceptible littermates and relatives to be at increased risk for similar adverse vaccine reactions (Dodds, 1997, 1999, 2001).

Dr. Schultz knows there's no benefit in over-vaccinating animals because immunity is not enhanced, but the risk of harmful adverse reactions is increased.

Addition of an unnecessary antigen to the vaccination protocol will result in a lesser immunity to the important diseases like parvovirus and distemper, and increase the risk of adverse reactions.

Lowering the required age of rabies vaccination to three months increases the likelihood of adverse vaccine reactions as well as failure to immunize due to residual maternal antibodies and interference from other puppy vaccines given at three months.

«Administration of multiple doses of parenteral vaccine at the same appointment, particularly among small breed dogs (< 10 kg), may increase the risk of an acute - onset adverse reaction.

Adverse reactions observed during clinical trials include vomiting, increased liver enzymes and transient loss of hearing.

In fact, while leptospira vaccines are commonly blamed for adverse reactions, recent studies have shown that incidence of adverse effects correlates only with: Lyme vaccination & / or use of increased number of separate vaccines concurrently.

Dr. Dodds feels the holistic veterinary community needs to document more case studies of adverse reactions and do cohort reports so that DVMs have access to information about predisposing factors that increase vaccine risks for certain pets.

The use of Clomicalm Tablets in conjunction with certain other drugs or when your dog has other illnesses may be contraindicated or increase the risks of adverse reactions.

The following adverse reactions have been reported associated with administration of Clomicalm Tablets: lethargy / depression, vomiting, diarrhea, elevation in liver enzymes, convulsion (s), increased heart rate, decreased heart rate, increased thirst and confusion.

In older animals, chest radiographs may be recommended to ensure that there is no pre-existing pathology in the heart or lungs that might increase the risk of an adverse reaction.

Adverse reactions may include decreased appetite, vomiting, diarrhea, dark or tarry stools, increased water consumption, increased urination, pale gums due to anemia, yellowing of gums, skin or white of the eye due to jaundice, lethargy, incoordination, seizure, or behavioral changes.

While international dog and cat vaccination guidelines warn that we should decrease companion animal vaccination, i.e. «we should aim to reduce the «vaccine load» on individual animals in order to minimize the potential for adverse reactions to vaccine products» [18], vaccination of humans is increasing at a startling rate.

Increased stress results in a number of adverse reactions, including immunosuppression and the creation of gastric ulcers, among other things.»

In cases such as the hazing death at M.I.T., the wrongful death of Milena DelValle in the «Big Dig» tunnel collapse, and the devastating adverse drug reaction suffered by a child after taking an over-the-counter medication, MBBB has helped its clients, while at the same time helping society through settlements that have created a safer environment for college students, increased access to defibrillators in public settings, and many other public improvements.

• Demonstrated expertise in monitoring patients» post-surgical vital signs to ensure their stability and wellbeing • Deep insight into operating equipment such as cardiac monitors and pulse oximeters and quickly diagnosing problems and responding promptly • Proficient in handling pain management by ensuring a thorough comprehension of pain medications and safe ways of administering them • Adept at handling patient - controlled analgesia pumps and IVs and epidural anesthesia to ensure patient comfort • Qualified to monitor patients for adverse reactions to anesthesia and pain management medications by employing deep insight into anesthesia and how it affects the human body • Hands - on experience in handling critical care procedures post-surgery to ensure increased patient safety and comfort • Proven ability to manage post-operative pain by administering pain medication and assisting patients recover from the effects of anesthesia • Competent at handling patients with post-operative nausea and vomiting by ensuring that steps are taken to ward off respiratory pneumonia and other life threatening conditions • Unmatched ability to assess patients» conditions in post-surgical environments and implement post-surgical treatment plans to ensure increased chances of patient recovery and comfort