Quantitative autistic traits are transmitted intergenerationally and
increase risk for autism spectrum disorders
Importance Maternal infections and fever during pregnancy are associated with
increased risk for autism spectrum disorders (ASDs).
Not exact matches
As ultrasounds have been standard practice
for checking up on baby's development and progress during pregnancy, it would be alarming if there is a connection between exposure to ultrasounds and
increased risk of being diagnosed with
autism.
Page and his colleagues, who use animal models to understand how
autism risk factors impact the developing brain and to identify potential treatments
for the condition, have found that animals with mutations in the
autism risk gene phosphatase and tensin homolog (Pten) mimic aspects of
autism, including
increased brain size, social deficits and
increased repetitive behavior.
The largest of its kind, the study examined genetic data in 100,000 individuals including 40,000 people with a diagnosis of schizophrenia and also found that some of the genes identified as
increasing risk for schizophrenia have previously been associated with other neurodevelopmental disorders, including intellectual disability and
autism spectrum disorders.
Premature babies are at an
increased risk for developing
autism spectrum disorder.
Incidence in the general population is about 1 %,
for example, so an 87 %
increase in ASD
risk due to SSRI use would raise a child's absolute
risk of developing
autism to roughly 2 %.
«The
risk for schizophrenia
increases 2-fold when a father is over 45 years of age, and the
risk for autism increases 2 -5-fold.
Many children with
Autism Spectrum Disorder face
increased risk of injury when they wander away from adults who care
for them.
«The evidence base
for a role
for maternal exposure to air pollution
increasing the
risk of
autism spectrum disorders is becoming quite strong,» said Weisskopf.
The team found that genetic variants that contribute to higher scores on the Eyes Test also
increase the
risk for anorexia, but not
autism.
For example, at least two of the autism - associated gene changes described in the paper were associated with increased risk for seizur
For example, at least two of the
autism - associated gene changes described in the paper were associated with
increased risk for seizur
for seizures.
Notably, the study reported no significant
increased risk of
autism for women who gave birth to singleton children.
This rare genetic disorder predisposes patients to
increased risks for multiple kinds of cancers as well as neurodevelopmental disorders such as
autism.
This approach has identified genes that are relevant to
for example
autism, as well as individual mutations that substantially
increase or decrease the
risk for e.g. cardiovascular disease.
We are exploring the mechanisms underlying how maternal infection
increases the
risk for schizophrenia and
autism in the offspring.
Children suffering from
autism have been reported to have low bone mineral density and
increased risk for fracture, yet the cellular origin of the bone phenotype remains unknown.
Researchers at the Carolina Institute
for Developmental Disabilities tracking age - related issues of
autism identified an
increased risk of Parkinson's disease in this high - impact paper.
While they aren't sure yet, the researchers note that the Zika virus resembles some infections that can
increase the
risk for mental illness later in life, like schizophrenia,
autism, and bipolar disorder.
According to researchers,
increased risk of miscarriage, neonatal health issues, preterm birth as well as the possibility of long term neurobehavioral problems, such as
autism, indicate that a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, should only be prescribed with extreme caution and with full counseling
for women suffering from depression and trying to fall pregnant.
Over the past several years, vitamin D deficiency has been associated with
increased risk for such brain - related disorders as Parkinson's disease, multiple sclerosis,
autism, and even dementia.
Gluten sensitivity
increases your
risk for type 1 diabetes, obesity, gastrointestinal cancers, brain disorders, and
autism.
It is also important
for physicians to be aware that the prevalence of celiac disease is
increased in certain high
risk groups, such as insulin dependent diabetics, people with either Down's syndrome, IgA deficiency or autoimmune thyroid diseases, Alzheimer's or
autism and children with juvenile arthritis.»
Autism is a «really complicated» disorder, and the evidence to date suggests that a combination of genes and so - called environmental factors — some of which may increase the risk of both autism and schizophrenia — are involved, says Patrick F. Sullivan, M.D., lead author of the study and director of the Center for Psychiatric Genomics at the University of North Carolina School of Medicine, in Chapel
Autism is a «really complicated» disorder, and the evidence to date suggests that a combination of genes and so - called environmental factors — some of which may
increase the
risk of both
autism and schizophrenia — are involved, says Patrick F. Sullivan, M.D., lead author of the study and director of the Center for Psychiatric Genomics at the University of North Carolina School of Medicine, in Chapel
autism and schizophrenia — are involved, says Patrick F. Sullivan, M.D., lead author of the study and director of the Center
for Psychiatric Genomics at the University of North Carolina School of Medicine, in Chapel Hill.
Perhaps
for this reason, the etiology of ASD is not well defined and the combinations of environmental and genetic factors that protect against or
increase risk of developing
autism are not well understood.
She calls on healthcare providers to assess dietary intake of dairy and protein in children with
autism as part of their wellness care and be mindful of the
increased risk for low bone density among these children.
«Widespread exposures to toxic chemicals in our air, water, food, soil, and consumer products can
increase the
risks for cognitive, behavioral, or social impairment, as well as specific neurodevelopmental disorders such as
autism and attention deficit hyperactivity disorder (ADHD).»
However, when they controlled
for comorbid attention problems, they found that the difference in injury
risk between the two groups all but disappeared, indicating to the researchers that attention problems, in children with or without
autism, may be the real factor behind the
increased injury
risk seen in previous studies.
Confirming previous reports, the results demonstrate that raising a child with
autism is associated with an
increased risk for both mental health difficulties and reduced wellbeing.
We hypothesized that the double hit conferred by sex and diagnosis
increases the
risk for internalizing disorders in adolescent females with
autism spectrum disorder (ASD).